(Q34234867)

31 July 2017

title

Posttranslational conversion of L-serines to D-alanines is vital for optimal production and activity of the lantibiotic lacticin 3147 (English)

1 reference

ORCID Public Data File 2021

31 July 2017

1 reference

author name string

Paul D Cotter

1

1 reference

31 July 2017

Paula M O'Connor

2

1 reference

31 July 2017

Lorraine A Draper

3

1 reference

31 July 2017

Elaine M Lawton

4

1 reference

31 July 2017

Lucy H Deegan

5

1 reference

31 July 2017

Colin Hill

6

1 reference

31 July 2017

R Paul Ross

7

1 reference

31 July 2017

language of work or name

English

0 references

publication date

8 December 2005

1 reference

Proceedings of the National Academy of Sciences of the United States of America

31 July 2017

published in

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31 July 2017

volume

102

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31 July 2017

issue

51

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31 July 2017

page(s)

18584-18589

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Sequential actions of the two component peptides of the lantibiotic lacticin 3147 explain its antimicrobial activity at nanomolar concentrations

31 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1317978

Biosynthesis of a D-amino acid in peptide linkage by an enzyme from frog skin secretions.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1317978

Bacterial lantibiotics: strategies to improve therapeutic potential.

6 July 2018

1 reference

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In vitro activity and potency of an intravenously injected antimicrobial peptide and its DL amino acid analog in mice infected with bacteria

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1317978

Structural and functional differences in two cyclic bacteriocins with the same sequences produced by lactobacilli

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1317978

Lacticin 481: in vitro reconstitution of lantibiotic synthetase activity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1317978

Construction of an expression system for site-directed mutagenesis of the lantibiotic mersacidin

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1317978

A food-grade approach for functional analysis and modification of native plasmids in Lactococcus lactis.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1317978

Complete nucleotide sequence of a Staphylococcus aureus exfoliative toxin B plasmid and identification of a novel ADP-ribosyltransferase, EDIN-C.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1317978

Improvement and optimization of two engineered phage resistance mechanisms in Lactococcus lactis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1317978

Nucleotide sequence and analysis of plasmid pMD136 from Pediococcus pentosaceus FBB61 (ATCC43200) involved in pediocin A production

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1317978

Effect of D-amino acid substitution on the stability, the secondary structure, and the activity of membrane-active peptide.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1317978

2D-NMR and ATR-FTIR study of the structure of a cell-selective diastereomer of melittin and its orientation in phospholipids.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1317978

Sequence and analysis of the 60 kb conjugative, bacteriocin-producing plasmid pMRC01 from Lactococcus lactis DPC3147.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1317978

Lacticin 3147, a broad-spectrum bacteriocin which selectively dissipates the membrane potential.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1317978

A general system for generating unlabelled gene replacements in bacterial chromosomes.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1317978

Diastereoisomers of cytolysins, a novel class of potent antibacterial peptides

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1317978

A system to generate chromosomal mutations in Lactococcus lactis which allows fast analysis of targeted genes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1317978

Peptides containing a D-amino acid from frogs and molluscs.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1317978

Plasmid complements of Streptococcus lactis NCDO 712 and other lactic streptococci after protoplast-induced curing.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1317978

N-terminal analogues of cecropin A: synthesis, antibacterial activity, and conformational properties.

6 July 2018

1 reference

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Gene splicing by overlap extension: tailor-made genes using the polymerase chain reaction

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1317978

Enter a new post-translational modification: D-amino acids in gene-encoded peptides

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1317978

Dehydroalanine-based inhibition of a peptide epimerase from spider venom

6 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0509371102

Folding of amphipathic alpha-helices on membranes: energetics of helix formation by melittin

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0509371102

Structural characterization of lacticin 3147, a two-peptide lantibiotic with synergistic activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0509371102

Lacticin 3147 displays activity in buffer against gram-positive bacterial pathogens which appear insensitive in standard plate assays.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0509371102

Each peptide of the two-component lantibiotic lacticin 3147 requires a separate modification enzyme for activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0509371102

Dynamic relationships among type IIa bacteriocins: temperature effects on antimicrobial activity and on structure of the C-terminal amphipathic alpha helix as a receptor-binding region

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0509371102

In vivo conversion of L-serine to D-alanine in a ribosomally synthesized polypeptide

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1317978

Two-component regulator of Enterococcus faecalis cytolysin responds to quorum-sensing autoinduction

28 October 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0509371102

Structural Relationships in Microbial Peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0509371102

Functional consequences of posttranslational isomerization of Ser46 in a calcium channel toxin

21 January 2018

1 reference

12 December 2020

Transformation of Lactococcus by electroporation

1 reference

12 December 2020

Selective lysis of bacteria but not mammalian cells by diastereomers of melittin: structure-function study

1 reference

12 December 2020

Extensive post-translational modification, including serine to D-alanine conversion, in the two-component lantibiotic, lacticin 3147

1 reference

12 December 2020

The consequence of sequence alteration of an amphipathic alpha-helical antimicrobial peptide and its diastereomers

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0509371102

1 reference

31 July 2017

0 references

1 reference

31 July 2017

1 reference