(Q34236724)

English

Peroxisome proliferator-activated receptor {gamma} coactivator 1{alpha} (PGC-1{alpha}) promotes skeletal muscle lipid refueling in vivo by activating de novo lipogenesis and the pentose phosphate pathway.

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scholarly article

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20716531%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

Peroxisome proliferator-activated receptor {gamma} coactivator 1{alpha} (PGC-1{alpha}) promotes skeletal muscle lipid refueling in vivo by activating de novo lipogenesis and the pentose phosphate pathway (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20716531%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

Christoph Handschin

5

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10 February 2020

author name string

Serge Summermatter

1

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10 February 2020

Oliver Baum

2

1 reference

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10 February 2020

Gesa Santos

3

1 reference

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10 February 2020

Hans Hoppeler

4

1 reference

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10 February 2020

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17 August 2010

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10 February 2020

Journal of Biological Chemistry

1 reference

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10 February 2020

285

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10 February 2020

43

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10 February 2020

32793-32800

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20716531%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

Increased intramuscular lipid synthesis and low saturation relate to insulin sensitivity in endurance-trained athletes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963391

6 July 2018

Dual modulation of both lipid oxidation and synthesis by peroxisome proliferator-activated receptor-gamma coactivator-1alpha and -1beta in cultured myotubes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963391

6 July 2018

Paradoxical effects of increased expression of PGC-1alpha on muscle mitochondrial function and insulin-stimulated muscle glucose metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963391

6 July 2018

AMPK and PPARdelta agonists are exercise mimetics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963391

6 July 2018

The role of exercise and PGC1alpha in inflammation and chronic disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963391

6 July 2018

Reduced physical activity and risk of chronic disease: the biology behind the consequences.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963391

6 July 2018

In appreciation of Sir Philip Randle: the glucose-fatty acid cycle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963391

6 July 2018

Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963391

6 July 2018

PGC-1alpha protects skeletal muscle from atrophy by suppressing FoxO3 action and atrophy-specific gene transcription

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963391

6 July 2018

Peroxisome proliferator-activated receptor gamma coactivator 1 coactivators, energy homeostasis, and metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963391

6 July 2018

PGC-1 coactivators: inducible regulators of energy metabolism in health and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963391

6 July 2018

Metabolic control through the PGC-1 family of transcription coactivators

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963391

6 July 2018

Exercise-induced increase in muscle insulin sensitivity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963391

6 July 2018

The glucose fatty-acid cycle. Its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963391

6 July 2018

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963391

28 October 2018

Bioenergetic analysis of peroxisome proliferator-activated receptor gamma coactivators 1alpha and 1beta (PGC-1alpha and PGC-1beta) in muscle cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963391

6 July 2018

Molecular basis of skeletal muscle plasticity--from gene to form and function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963391

6 July 2018

Transcriptional co-activator PGC-1 alpha drives the formation of slow-twitch muscle fibres

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963391

6 July 2018

Intramyocellular triglyceride content is a determinant of in vivo insulin resistance in humans: a 1H-13C nuclear magnetic resonance spectroscopy assessment in offspring of type 2 diabetic parents.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963391

6 July 2018

Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963391

6 July 2018

Methods for studying the glucose-6-phosphate dehydrogenase activity in brain areas.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963391

6 July 2018

Incorporation of [6-3H] glucose into lipid, protein, RNA and DNA of slices of differentiating rat cerebral cortex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963391

6 July 2018

Effect of 10 days of physical inactivity on glucose tolerance in master athletes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963391

6 July 2018

Plasma membrane fatty acid-binding protein and mitochondrial glutamic-oxaloacetic transaminase of rat liver are related

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963391

6 July 2018

Increased gene expression of lipogenic enzymes and glucose transporter in white adipose tissue of suckling and weaned obese Zucker rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963391

6 July 2018

Acute effects in vivo of anti-insulin serum on rates of fatty acid synthesis and activities of acetyl-coenzyme A carboxylase and pyruvate dehydrogenase in liver and epididymal adipose tissue of fed rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963391

6 July 2018

Adaptations of skeletal muscle to exercise: rapid increase in the transcriptional coactivator PGC-1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.145995

21 January 2018

Endurance training in humans leads to fiber type-specific increases in levels of peroxisome proliferator-activated receptor-gamma coactivator-1 and peroxisome proliferator-activated receptor-alpha in skeletal muscle.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.145995

21 January 2018

Muscle-specific expression of PPARgamma coactivator-1alpha improves exercise performance and increases peak oxygen uptake

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.145995

21 January 2018

Intramyocellular lipid content in type 2 diabetes patients compared with overweight sedentary men and highly trained endurance athletes.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.145995

21 January 2018

Significant intramyocellular lipid use during prolonged cycling in endurance-trained males as assessed by three different methodologies.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.145995

21 January 2018

A role for the transcriptional coactivator PGC-1alpha in muscle refueling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.145995

21 January 2018

Association of increased intramyocellular lipid content with insulin resistance in lean nondiabetic offspring of type 2 diabetic subjects.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.145995

21 January 2018

Identification of fatty acid translocase on human skeletal muscle mitochondrial membranes: essential role in fatty acid oxidation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.145995

21 January 2018

Dietary whey protein downregulates fatty acid synthesis in the liver, but upregulates it in skeletal muscle of exercise-trained rats

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.145995

21 January 2018

Effect of 2-month detraining on body composition and insulin sensitivity in young female dancers

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.145995

21 January 2018

Effects of short-term detraining on measures of obesity and glucose tolerance in elite athletes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.145995

21 January 2018

Rapid down-regulation of mitochondrial fat metabolism in human muscle after training cessation is dissociated from changes in insulin sensitivity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.145995

21 January 2018

High-fat diet, muscular lipotoxicity and insulin resistance

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.145995

21 January 2018

The exercise pill--too good to be true?

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.145995

21 January 2018

Can exercise mimetics substitute for exercise?

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.145995

21 January 2018

Skeletal muscle lipid content and insulin resistance: evidence for a paradox in endurance-trained athletes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963391

28 October 2018

In vivo evaluation of the effects of continuous exercise on skeletal muscle triglycerides in trained humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/20716531

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stimulation of fatty acid biosynthesis by dietary cholesterol and of cholesterol synthesis by dietary fatty acid

1 reference

https://pubmed.ncbi.nlm.nih.gov/20716531

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Suitability of 2-deoxyglucose for in vitro measurement of glucose transport activity in skeletal muscle

1 reference

https://pubmed.ncbi.nlm.nih.gov/20716531

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lipotoxicity: the obese and endurance-trained paradox

1 reference

https://pubmed.ncbi.nlm.nih.gov/20716531

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Training high--living low: changes of aerobic performance and muscle structure with training at simulated altitude

1 reference

https://pubmed.ncbi.nlm.nih.gov/20716531

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M110.145995

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20716531%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20716531%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20716531%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

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