(Q34238028)

31 July 2017

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title

Versatility of the mitochondrial protein import machinery (English)

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31 July 2017

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Pfanner N

1

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PubMed ID

11331908

31 July 2017

Geissler A

series ordinal

2

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31 July 2017

1 May 2001

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Nature Reviews Molecular Cell Biology

31 July 2017

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31 July 2017

2

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31 July 2017

339-349

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31 July 2017

5

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https://scigraph.springernature.com/pub.10.1038/35073006

31 July 2017

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cites work

Intracellular protein topogenesis

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7 January 2021

Kinetic Studies on the Transport of Cytoplasmically Synthesized Proteins into the Mitochondria in Intact Cells of Neurospora crassa

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7 January 2021

Protein folding causes an arrest of preprotein translocation into mitochondria in vivo

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7 January 2021

The cleavable prepiece of an imported mitochondrial protein is sufficient to direct cytosolic dihydrofolate reductase into the mitochondrial matrix

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7 January 2021

Distribution of binding sequences for the mitochondrial import receptors Tom20, Tom22, and Tom70 in a presequence-carrying preprotein and a non-cleavable preprotein.

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7 January 2021

Transport of Proteins into Mitochondria. Posttranslational Transfer of ADP/ATP Carrier into Mitochondria in vitro

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7 January 2021

Binding of mitochondrial precursor proteins to the cytoplasmic domains of the import receptors Tom70 and Tom20 is determined by cytoplasmic chaperones

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7 January 2021

Mapping of the protein import machinery in the mitochondrial outer membrane by crosslinking of translocation intermediates

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7 January 2021

Differential recognition of preproteins by the purified cytosolic domains of the mitochondrial import receptors Tom20, Tom22, and Tom70.

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7 January 2021

Structural basis of presequence recognition by the mitochondrial protein import receptor Tom20

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7 January 2021

Binding of a specific ligand inhibits import of a purified precursor protein into mitochondria.

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7 January 2021

The three modules of ADP/ATP carrier cooperate in receptor recruitment and translocation into mitochondria

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7 January 2021

Preprotein translocase of the outer mitochondrial membrane: molecular dissection and assembly of the general import pore complex

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7 January 2021

The preprotein translocation channel of the outer membrane of mitochondria.

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7 January 2021

The Tim core complex defines the number of mitochondrial translocation contact sites and can hold arrested preproteins in the absence of matrix Hsp70-Tim44.

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7 January 2021

Role of Tim23 as voltage sensor and presequence receptor in protein import into mitochondria

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7 January 2021

Tim23, a protein import component of the mitochondrial inner membrane, is required for normal activity of the multiple conductance channel, MCC.

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7 January 2021

Requirement for hsp70 in the mitochondrial matrix for translocation and folding of precursor proteins

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7 January 2021

Sequential action of two hsp70 complexes during protein import into mitochondria

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7 January 2021

Differential requirement for the mitochondrial Hsp70-Tim44 complex in unfolding and translocation of preproteins.

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7 January 2021

Mitochondrial protein import: identification of processing peptidase and of PEP, a processing enhancing protein.

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7 January 2021

Protein folding in mitochondria requires complex formation with hsp60 and ATP hydrolysis

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7 January 2021

Cyclophilin 20 is involved in mitochondrial protein folding in cooperation with molecular chaperones Hsp70 and Hsp60

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7 January 2021

Import of carrier proteins into the mitochondrial inner membrane mediated by Tim22.

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7 January 2021

The Tim54p-Tim22p complex mediates insertion of proteins into the mitochondrial inner membrane

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7 January 2021

Import of mitochondrial carriers mediated by essential proteins of the intermembrane space

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7 January 2021

Carrier protein import into mitochondria mediated by the intermembrane proteins Tim10/Mrs11 and Tim12/Mrs5.

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7 January 2021

Domain structure of mitochondrial and chloroplast targeting peptides

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7 January 2021

Cloning and disruption of the gene encoding yeast mitochondrial chaperonin 10, the homolog of E. coli groES.

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7 January 2021

The DNA helicase, Hmi1p, is transported into mitochondria by a C-terminal cleavable targeting signal

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7 January 2021

Cytochromes c1 and b2 are sorted to the intermembrane space of yeast mitochondria by a stop-transfer mechanism

1 reference

7 January 2021

Incomplete arrest in the outer membrane sorts NADH-cytochrome b5 reductase to two different submitochondrial compartments

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7 January 2021

The sorting signal of cytochrome b2 promotes early divergence from the general mitochondrial import pathway and restricts the unfoldase activity of matrix Hsp70.

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7 January 2021

The signal that sorts yeast cytochrome b2 to the mitochondrial intermembrane space contains three distinct functional regions

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7 January 2021

The sorting route of cytochrome b2 branches from the general mitochondrial import pathway at the preprotein translocase of the inner membrane

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7 January 2021

Mitochondrial import of subunit Va of cytochrome c oxidase characterized with yeast mutants

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7 January 2021

A mitochondrial protease with two catalytic subunits of nonoverlapping specificities.

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7 January 2021

Transport into mitochondria and intramitochondrial sorting of the Fe/S protein of ubiquinol-cytochrome c reductase

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7 January 2021

Transport of the ADP/ATP carrier of mitochondria from the TOM complex to the TIM22.54 complex

1 reference

7 January 2021

The mitochondrial import receptor Tom70: identification of a 25 kDa core domain with a specific binding site for preproteins

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7 January 2021

Tim23p contains separate and distinct signals for targeting to mitochondria and insertion into the inner membrane

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7 January 2021

Two intermembrane space TIM complexes interact with different domains of Tim23p during its import into mitochondria

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7 January 2021

The role of the TIM8-13 complex in the import of Tim23 into mitochondria

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7 January 2021

The TOM core complex: the general protein import pore of the outer membrane of mitochondria.

1 reference

7 January 2021

Tom22 is a multifunctional organizer of the mitochondrial preprotein translocase.

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7 January 2021

Protein import channel of the outer mitochondrial membrane: a highly stable Tom40-Tom22 core structure differentially interacts with preproteins, small tom proteins, and import receptors

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7 January 2021

Tom5 functionally links mitochondrial preprotein receptors to the general import pore.

1 reference

7 January 2021

Biogenesis of Tim proteins of the mitochondrial carrier import pathway: differential targeting mechanisms and crossing over with the main import pathway

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7 January 2021

Tom40 forms the hydrophilic channel of the mitochondrial import pore for preproteins [see comment].

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7 January 2021

A yeast mitochondrial outer membrane protein essential for protein import and cell viability

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7 January 2021

The dimensions of the protein import channels in the outer and inner mitochondrial membranes

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7 January 2021

The intermembrane space domain of mitochondrial Tom22 functions as a trans binding site for preproteins with N-terminal targeting sequences

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7 January 2021

Interaction of mitochondrial targeting signals with acidic receptor domains along the protein import pathway: evidence for the 'acid chain' hypothesis

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7 January 2021

Tom7 modulates the dynamics of the mitochondrial outer membrane translocase and plays a pathway-related role in protein import

1 reference

7 January 2021

Biogenesis of porin of the outer mitochondrial membrane involves an import pathway via receptors and the general import pore of the TOM complex

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7 January 2021

Disrupted yeast mitochondria can import precursor proteins directly through their inner membrane

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7 January 2021

Dynamic interaction of the protein translocation systems in the inner and outer membranes of yeast mitochondria.

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7 January 2021

MAS6 encodes an essential inner membrane component of the yeast mitochondrial protein import pathway

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7 January 2021

The polytopic mitochondrial inner membrane proteins MIM17 and MIM23 operate at the same preprotein import site

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7 January 2021

Tim23 links the inner and outer mitochondrial membranes.

1 reference

7 January 2021

Membrane potential-driven protein import into mitochondria. The sorting sequence of cytochrome b(2) modulates the deltapsi-dependence of translocation of the matrix-targeting sequence

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7 January 2021

The protein import motor of mitochondria: unfolding and trapping of preproteins are distinct and separable functions of matrix Hsp70

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7 January 2021

Mitochondrial protein import motor: the ATPase domain of matrix Hsp70 is crucial for binding to Tim44, while the peptide binding domain and the carboxy-terminal segment play a stimulatory role

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7 January 2021

Active unfolding of precursor proteins during mitochondrial protein import

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7 January 2021

Unfolding of preproteins upon import into mitochondria

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7 January 2021

Strong precursor-pore interactions constrain models for mitochondrial protein import

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7 January 2021

Mitochondria Unfold Precursor Proteins by Unraveling Them From Their N-termini

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7 January 2021

Multiple interactions of components mediating preprotein translocation across the inner mitochondrial membrane

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7 January 2021

Tim18p is a new component of the Tim54p-Tim22p translocon in the mitochondrial inner membrane

1 reference

7 January 2021

Tim18p, a new subunit of the TIM22 complex that mediates insertion of imported proteins into the yeast mitochondrial inner membrane

1 reference

7 January 2021

Mitochondrial protein import: nucleoside triphosphates are involved in conferring import-competence to precursors

1 reference

7 January 2021

The import route of ADP/ATP carrier into mitochondria separates from the general import pathway of cleavable preproteins at the trans side of the outer membrane.

1 reference

7 January 2021

Tim9p, an essential partner subunit of Tim10p for the import of mitochondrial carrier proteins

1 reference

7 January 2021

Tim9, a new component of the TIM22.54 translocase in mitochondria

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7 January 2021

Human deafness dystonia syndrome is a mitochondrial disease

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7 January 2021

Different import pathways through the mitochondrial intermembrane space for inner membrane proteins

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7 January 2021

An internal targeting signal directing proteins into the mitochondrial intermembrane space

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7 January 2021

Import of ADP/ATP carrier into mitochondria: two receptors act in parallel

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7 January 2021

Cytoplasmic type 80S ribosomes associated with yeast mitochondria. IV. Attachment of ribosomes to the outer membrane of isolated mitochondria

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7 January 2021

Nascent polypeptide-associated complex stimulates protein import into yeast mitochondria

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7 January 2021

Import into Mitochondria, Folding and Retrograde Movement of Fumarase in Yeast

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7 January 2021

Recognition of preproteins by the isolated TOM complex of mitochondria

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7 January 2021

Insertion of MOM22 into the mitochondrial outer membrane strictly depends on surface receptors

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7 January 2021

Biogenesis of Tom40, core component of the TOM complex of mitochondria

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7 January 2021

Multistep assembly of the protein import channel of the mitochondrial outer membrane.

1 reference

7 January 2021

Membrane translocation of mitochondrially coded Cox2p: distinct requirements for export of N and C termini and dependence on the conserved protein Oxa1p

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7 January 2021

Oxa1p, an essential component of the N-tail protein export machinery in mitochondria

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7 January 2021

YidC mediates membrane protein insertion in bacteria

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7 January 2021

Mutations affecting a yeast mitochondrial inner membrane protein, pnt1p, block export of a mitochondrially synthesized fusion protein from the matrix

1 reference

7 January 2021

The TIM17.23 preprotein translocase of mitochondria: composition and function in protein transport into the matrix

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7 January 2021

Identifiers

DOI

10.1038/35073006

1 reference

PubMed ID

11331908

Dimensions Publication ID

31 July 2017

0 references

1 reference

PubMed ID

11331908