(Q34242706)

31 July 2017

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title

Mutant T cell lines as model systems for the dissection of T cell antigen receptor signaling pathways (English)

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31 July 2017

Abraham RT

1

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31 July 2017

1 January 2000

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31 July 2017

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31 July 2017

22

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31 July 2017

2-3

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31 July 2017

95-117

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https://scigraph.springernature.com/pub.10.1385/ir:22:2-3:95

31 July 2017

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cites work

Phosphorylation of Tyr319 in ZAP-70 is required for T-cell antigen receptor-dependent phospholipase C-gamma1 and Ras activation

1 reference

12 December 2020

Calcium oscillations increase the efficiency and specificity of gene expression

1 reference

12 December 2020

Absence of ZAP-70 prevents signaling through the antigen receptor on peripheral blood T cells but not on thymocytes

1 reference

12 December 2020

Differential intrinsic enzymatic activity of Syk and Zap-70 protein-tyrosine kinases

1 reference

12 December 2020

Uncoupling of nonreceptor tyrosine kinases from PLC-gamma1 in an SLP-76-deficient T cell

1 reference

12 December 2020

The immunological synapse: a molecular machine controlling T cell activation

1 reference

12 December 2020

Protein kinase C-theta isoenzyme selective stimulation of the transcription factor complex AP-1 in T lymphocytes

1 reference

12 December 2020

Differential signaling by lymphocyte antigen receptors.

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12 December 2020

RasGRP links T-cell receptor signaling to Ras

1 reference

12 December 2020

Isolation and characterization of a T-lymphocyte somatic mutant with altered signal transduction by the antigen receptor.

1 reference

12 December 2020

Syk Mutation in Jurkat E6-derived Clones Results in Lack of p72syk Expression

1 reference

12 December 2020

LAT is required for TCR-mediated activation of PLCgamma1 and the Ras pathway

1 reference

12 December 2020

PKC-θ is required for TCR-induced NF-κB activation in mature but not immature T lymphocytes

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12 December 2020

The Syk protein tyrosine kinase can function independently of CD45 or Lck in T cell antigen receptor signaling

1 reference

12 December 2020

LAT: the ZAP-70 tyrosine kinase substrate that links T cell receptor to cellular activation

1 reference

12 December 2020

Analysis of the role of protein kinase C-alpha, -epsilon, and -zeta in T cell activation

1 reference

12 December 2020

Antiproliferative action of interferon-α requires components of T-cell-receptor signalling

1 reference

12 December 2020

Human severe combined immunodeficiency due to a defect in ZAP-70, a T cell tyrosine kinase

1 reference

12 December 2020

RasGRP, a Ras guanyl nucleotide- releasing protein with calcium- and diacylglycerol-binding motifs

1 reference

12 December 2020

PDGF stimulation of inositol phospholipid hydrolysis requires PLC-gamma 1 phosphorylation on tyrosine residues 783 and 1254.

1 reference

12 December 2020

Sequential interactions of the TCR with two distinct cytoplasmic tyrosine kinases

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12 December 2020

Functional independence and interdependence of the Src homology domains of phospholipase C-gamma1 in B-cell receptor signal transduction.

1 reference

12 December 2020

CD28 mediates transcriptional upregulation of the interleukin-2 (IL-2) promoter through a composite element containing the CD28RE and NF-IL-2B AP-1 sites

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12 December 2020

Genetic evidence for the involvement of the lck tyrosine kinase in signal transduction through the T cell antigen receptor

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12 December 2020

A protein tyrosine kinase in the interferon alpha/beta signaling pathway

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12 December 2020

Cbl: complex formation and functional implications

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12 December 2020

Phospholipase C-gamma1: regulation of enzyme function and role in growth factor-dependent signal transduction

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12 December 2020

Stimulatory effects of the protein tyrosine phosphatase inhibitor, pervanadate, on T-cell activation events.

1 reference

12 December 2020

Requirement for p53 and p21 to sustain G2 arrest after DNA damage

1 reference

12 December 2020

Stimulation of p21 ras upon T-cell activation

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12 December 2020

Tyrosine 319 in the interdomain B of ZAP-70 is a binding site for the Src homology 2 domain of Lck

1 reference

12 December 2020

Protein kinase Ctheta, a selective upstream regulator of JNK/SAPK and IL-2 promoter activation in Jurkat T cells

1 reference

12 December 2020

Signal transmission between the plasma membrane and nucleus of T lymphocytes

1 reference

12 December 2020

Phospholipase Cgamma2 is essential in the functions of B cell and several Fc receptors

1 reference

12 December 2020

Tyrosine phosphatase CD45 is required for T-cell antigen receptor and CD2-mediated activation of a protein tyrosine kinase and interleukin 2 production

1 reference

12 December 2020

Calcium and T lymphocyte activation

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12 December 2020

ITAM multiplicity and thymocyte selection: how low can you go?

1 reference

12 December 2020

Association of Grb2, Gads, and phospholipase C-gamma 1 with phosphorylated LAT tyrosine residues. Effect of LAT tyrosine mutations on T cell angigen receptor-mediated signaling

1 reference

12 December 2020

A novel functional interaction between Vav and PKCtheta is required for TCR-induced T cell activation.

1 reference

12 December 2020

T cell receptor-initiated calcium release is uncoupled from capacitative calcium entry in Itk-deficient T cells

1 reference

12 December 2020

The tyrosine kinase negative regulator c-Cbl as a RING-type, E2-dependent ubiquitin-protein ligase

1 reference

12 December 2020

Models of T cell anergy: is there a common molecular mechanism?

1 reference

12 December 2020

Defective T cell receptor signaling and CD8+ thymic selection in humans lacking zap-70 kinase

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12 December 2020

NF-kappa B activation induced by T cell receptor/CD28 costimulation is mediated by protein kinase C-theta

1 reference

12 December 2020

RING for destruction?

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12 December 2020

Selective modulation of protein kinase C-theta during T-cell activation

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12 December 2020

Requirement for Tec kinases Rlk and Itk in T cell receptor signaling and immunity

1 reference

12 December 2020

Nuclear factor of activated T cells and AP-1 are insufficient for IL-2 promoter activation: requirement for CD28 up-regulation of RE/AP.

1 reference

12 December 2020

Use of somatic cell mutants to study the signal transduction function of the T cell antigen receptor

1 reference

12 December 2020

ZAP-70 deficiency in an autosomal recessive form of severe combined immunodeficiency

1 reference

12 December 2020

Role of protein kinase C in T-cell antigen receptor regulation of p21ras: evidence that two p21ras regulatory pathways coexist in T cells

1 reference

12 December 2020

Reconstitution of T cell antigen receptor-induced Erk2 kinase activation in Lck-negative JCaM1 cells by Syk

1 reference

12 December 2020

The tyrosine activation motif as a target of protein tyrosine kinases and SH2 domains

1 reference

12 December 2020

Phosphoinositide-specific phospholipase C and mitogenic signaling

1 reference

12 December 2020

Use of a selectable marker regulated by alpha interferon to obtain mutations in the signaling pathway

1 reference

12 December 2020

Gene targeting and somatic cell genetics--a rebirth or a coming of age?

1 reference

12 December 2020

Sequences surrounding the Src-homology 3 domain of phospholipase Cgamma-1 increase the domain's association with Cbl

1 reference

12 December 2020

Differential expression of ZAP-70 and Syk protein tyrosine kinases, and the role of this family of protein tyrosine kinases in TCR signaling

1 reference

12 December 2020

The Syk family of protein tyrosine kinases in T-cell activation and development

1 reference

12 December 2020

Identification by electrospray ionization mass spectrometry of the sites of tyrosine phosphorylation induced in activated Jurkat T cells on the protein tyrosine kinase ZAP-70

1 reference

12 December 2020

Molecular basis for interaction of the protein tyrosine kinase ZAP-70 with the T-cell receptor

1 reference

12 December 2020

The amino-terminal Src homology 2 domain of phospholipase C gamma 1 is essential for TCR-induced tyrosine phosphorylation of phospholipase C gamma 1

1 reference

12 December 2020

Isolation and characterization of a new mutant human cell line unresponsive to alpha and beta interferons

1 reference

12 December 2020

Genetic evidence for differential coupling of Syk family kinases to the T-cell receptor: reconstitution studies in a ZAP-70-deficient Jurkat T-cell line

1 reference

12 December 2020

Differential effects of Cbl and 70Z/3 Cbl on T cell receptor-induced phospholipase Cgamma-1 activity.

1 reference

12 December 2020

The guanine nucleotide exchange factor RasGRP is a high -affinity target for diacylglycerol and phorbol esters.

1 reference

12 December 2020

Three-dimensional segregation of supramolecular activation clusters in T cells

1 reference

12 December 2020

Activation of Zap-70 tyrosine kinase due to a structural rearrangement induced by tyrosine phosphorylation and/or ITAM binding

1 reference

12 December 2020

Molecular regulation of interleukin-2 expression by CD28 co-stimulation and anergy

1 reference

12 December 2020

The ups and downs of T cell costimulation

1 reference

12 December 2020

Tec family kinases in lymphocyte signaling and function

1 reference

12 December 2020

Tyrosine 319, a newly identified phosphorylation site of ZAP-70, plays a critical role in T cell antigen receptor signaling

1 reference

12 December 2020

The role of protein kinase C in the regulation of extracellular signal-regulated kinase by the T cell antigen receptor.

1 reference

12 December 2020

Identifiers

DOI

10.1385/IR:22:2-3:95

1 reference

PubMed ID

11339369

Dimensions Publication ID

31 July 2017

0 references

1 reference

PubMed ID

11339369