(Q34244966)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16365317%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

title

Opioid-induced tolerance and dependence in mice is modulated by the distance between pharmacophores in a bivalent ligand series (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16365317%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

0 references

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16365317%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

author name string

David J Daniels

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16365317%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

Natalie R Lenard

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16365317%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

Chris L Etienne

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16365317%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

Sandra C Roerig

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16365317%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

Philip S Portoghese

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16365317%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

language of work or name

English

0 references

publication date

19 December 2005

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16365317%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

10 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16365317%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

volume

102

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16365317%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

issue

52

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16365317%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

page(s)

19208-19213

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16365317%20AND%20SRC:MED&resulttype=core&format=json

Interaction of bivalent ligand KDN21 with heterodimeric delta-kappa opioid receptors in human embryonic kidney 293 cells

10 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1323165

A role for heterodimerization of mu and delta opiate receptors in enhancing morphine analgesia

28 July 2018

1 reference

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Pharmacological effects produced by intracerebral injection of drugs in the conscious mouse

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1323165

Unifying perspectives of the mechanisms underlying the development of tolerance and physical dependence to opioids.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1323165

Antisense oligodeoxynucleotides to opioid mu and delta receptors reduced morphine dependence in mice: role of delta-2 opioid receptors

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1323165

An antisense oligodeoxynucleotide to the delta opioid receptor (DOR-1) inhibits morphine tolerance and acute dependence in mice

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1323165

Involvement of delta 2 opioid receptors in the development of morphine dependence in mice

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1323165

Narcotic antagonistic potency of bivalent ligands which contain beta-naltrexamine. Evidence for bridging between proximal recognition sites

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1323165

Dimeric pentapeptide enkephalin: A novel probe of delta opiate receptors

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1323165

Opioid agonist and antagonist bivalent ligands as receptor probes

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1323165

Opiate receptor binding studies in the mouse vas deferens exhibiting tolerance without dependence

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1323165

Increased biological activity of dimers of oxymorphone and enkephalin: Possible role of receptor crosslinking

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1323165

Opioid agonist and antagonist bivalent ligands. The relationship between spacer length and selectivity at multiple opioid receptors

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1323165

Synthesis and opioid antagonist potencies of naltrexamine bivalent ligands with conformationally restricted spacers

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1323165

Stereostructure-activity relationship of opioid agonist and antagonist bivalent ligands. Evidence for bridging between vicinal opioid receptors

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1323165

Hybrid bivalent ligands with opiate and enkephalin pharmacophores

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1323165

Design of peptidomimetic delta opioid receptor antagonists using the message-address concept

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1323165

Long-acting agonist and antagonist activities of naltrexamine bivalent ligands in mice

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1323165

Binding to opioid receptors of enkephalin derivatives taking alpha-helical conformation and its dimer

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1323165

Differential effects of leucine and methionine enkephalin on morphine-induced analgesia, acute tolerance and dependence

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1323165

Mu and delta receptors: Their role in analgesia and in the differential effects of opioid peptides on analgesia

28 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0506627102

Attenuation of morphine tolerance and dependence with the highly selective delta-opioid receptor antagonist TIPP[psi].

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0506627102

Retention of supraspinal delta-like analgesia and loss of morphine tolerance in delta opioid receptor knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0506627102

The opioid mu agonist/delta antagonist DIPP-NH(2)[Psi] produces a potent analgesic effect, no physical dependence, and less tolerance than morphine in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0506627102

Synthesis, opioid receptor binding, and biological activities of naltrexone-derived pyrido- and pyrimidomorphinans

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0506627102

Oligomerization of mu- and delta-opioid receptors. Generation of novel functional properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0506627102

Dimeric tetrapeptide enkephalins display extraordinary selectivity for the delta opiate receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0506627102

Receptor binding and biological activity of bivalent enkephalins

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0506627102

A bivalent ligand (KDN-21) reveals spinal delta and kappa opioid receptors are organized as heterodimers that give rise to delta(1) and kappa(2) phenotypes. Selective targeting of delta-kappa heterodimers

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0506627102

A bivalent ligand (KDAN-18) containing delta-antagonist and kappa-agonist pharmacophores bridges delta2 and kappa1 opioid receptor phenotypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0506627102

A heterodimer-selective agonist shows in vivo relevance of G protein-coupled receptor dimers

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0506627102

From models to molecules: opioid receptor dimers, bivalent ligands, and selective opioid receptor probes

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0506627102

Dimerization of the delta opioid receptor: implication for a role in receptor internalization

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0506627102

In vivo pharmacological characterization of SoRI 9409, a nonpeptidic opioid mu-agonist/delta-antagonist that produces limited antinociceptive tolerance and attenuates morphine physical dependence.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1323165

Different mechanisms mediate development and expression of tolerance and dependence for peripheral mu-opioid antinociception in rat.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1323165

Lack of involvement of delta-1 opioid receptors in the development of physical dependence on morphine in mice.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1323165

Selective blockage of delta opioid receptors prevents the development of morphine tolerance and dependence in mice

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1323165

Simultaneous quantitative assessment of morphine tolerance and physical dependence

28 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16365317

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0506627102

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16365317%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16365317%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

PubMed publication ID

16365317

1 reference