(Q34247022)

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A peptide inhibitor of c-Jun N-terminal kinase protects against both aminoglycoside and acoustic trauma-induced auditory hair cell death and hearing loss.

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:13679429%20AND%20SRC:MED&resulttype=core&format=json

16 December 2019

A peptide inhibitor of c-Jun N-terminal kinase protects against both aminoglycoside and acoustic trauma-induced auditory hair cell death and hearing loss (English)

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Europe PubMed Central

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16 December 2019

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5

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16 December 2019

author name string

J Wang

1

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16 December 2019

T R Van De Water

2

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16 December 2019

C Bonny

3

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16 December 2019

F de Ribaupierre

4

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16 December 2019

A Zine

6

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16 December 2019

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1 September 2003

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16 December 2019

Journal of Neuroscience

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16 December 2019

23

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16 December 2019

24

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16 December 2019

8596-8607

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16 December 2019

Tissue-specific levels and cellular distribution of epidermal growth factor receptors within control and neomycin-damaged neonatal rat Organ of Corti

1 reference

https://pubmed.ncbi.nlm.nih.gov/13679429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Attenuation of aminoglycoside-induced cochlear damage with the metabolic antioxidant alpha-lipoic acid

1 reference

https://pubmed.ncbi.nlm.nih.gov/13679429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

L- and D- methionine provide equivalent long term protection against CDDP-induced ototoxicity in vivo, with partial in vitro and in vivo retention of antineoplastic activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/13679429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptotic death of hair cells in mammalian vestibular sensory epithelia

1 reference

https://pubmed.ncbi.nlm.nih.gov/13679429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rescue of hearing, auditory hair cells, and neurons by CEP-1347/KT7515, an inhibitor of c-Jun N-terminal kinase activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/13679429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intense noise-induced apoptosis in hair cells of guinea pig cochleae

1 reference

https://pubmed.ncbi.nlm.nih.gov/13679429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Requirement of JNK for stress-induced activation of the cytochrome c-mediated death pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/13679429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Signal transduction by the JNK group of MAP kinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/13679429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cell-permeable peptide inhibitors of JNK: novel blockers of beta-cell death

1 reference

https://pubmed.ncbi.nlm.nih.gov/13679429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cep-1347 (KT7515), a semisynthetic inhibitor of the mixed lineage kinase family.

1 reference

https://pubmed.ncbi.nlm.nih.gov/13679429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Round window membrane delivery of L-methionine provides protection from cisplatin ototoxicity without compromising chemotherapeutic efficacy

1 reference

https://pubmed.ncbi.nlm.nih.gov/13679429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of the c-Jun N-terminal kinase signaling pathway by the mixed lineage kinase inhibitor CEP-1347 (KT7515) preserves metabolism and growth of trophic factor-deprived neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/13679429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of the critical features of a small peptide inhibitor of JNK activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/13679429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activity profile of calpains I and II in chronically infarcted rat myocardium--influence of the calpain inhibitor CAL 9961.

1 reference

https://pubmed.ncbi.nlm.nih.gov/13679429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Riluzole rescues cochlear sensory cells from acoustic trauma in the guinea-pig.

1 reference

https://pubmed.ncbi.nlm.nih.gov/13679429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Blockade of c-Jun N-terminal kinase pathway attenuates gentamicin-induced cochlear and vestibular hair cell death

1 reference

https://pubmed.ncbi.nlm.nih.gov/13679429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Involvement of apoptosis in progression of cochlear lesion following exposure to intense noise

1 reference

https://pubmed.ncbi.nlm.nih.gov/13679429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rescue of auditory hair cells from aminoglycoside toxicity by Clostridium difficile toxin B, an inhibitor of the small GTPases Rho/Rac/Cdc42.

1 reference

https://pubmed.ncbi.nlm.nih.gov/13679429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of the c-Jun N-terminal kinase signaling pathway influences neurite outgrowth of spiral ganglion neurons in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/13679429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

POSH acts as a scaffold for a multiprotein complex that mediates JNK activation in apoptosis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/13679429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biphasic and synergistic activation of p44mapk (ERK1) by growth factors: correlation between late phase activation and mitogenicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/13679429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1 reference

https://pubmed.ncbi.nlm.nih.gov/13679429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

c-Jun dimerizes with itself and with c-Fos, forming complexes of different DNA binding affinities

1 reference

https://pubmed.ncbi.nlm.nih.gov/13679429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Periods of sensitivity to antibiotic treatment

1 reference

https://pubmed.ncbi.nlm.nih.gov/13679429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Outer hair cell loss and supporting cell expansion following chronic gentamicin treatment

1 reference

https://pubmed.ncbi.nlm.nih.gov/13679429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cellular pattern and nerve supply of the human organ of Corti

1 reference

https://pubmed.ncbi.nlm.nih.gov/13679429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Development of the inner ear of the mouse: a radioautographic study of terminal mitoses

1 reference

https://pubmed.ncbi.nlm.nih.gov/13679429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Electrophysiological and morphological correlates in the guinea pig cochlea after exposure to 'impulsive' noise.

1 reference

https://pubmed.ncbi.nlm.nih.gov/13679429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transcription factor ATF2 regulation by the JNK signal transduction pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/13679429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/13679429

12 December 2020

based on heuristic

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Sulfhydryl compounds and antioxidants inhibit cytotoxicity to outer hair cells of a gentamicin metabolite in vitro.

1 reference

https://pubmed.ncbi.nlm.nih.gov/13679429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

EGF triggers neuronal differentiation of PC12 cells that overexpress the EGF receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/13679429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain

1 reference

https://pubmed.ncbi.nlm.nih.gov/13679429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The stress-activated protein kinase subfamily of c-Jun kinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/13679429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Formation of free radicals by gentamicin and iron and evidence for an iron/gentamicin complex.

1 reference

https://pubmed.ncbi.nlm.nih.gov/13679429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Direct detection of ototoxicant-induced reactive oxygen species generation in cochlear explants

1 reference

https://pubmed.ncbi.nlm.nih.gov/13679429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reactive oxygen species in chick hair cells after gentamicin exposure in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/13679429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A Truncated HIV-1 Tat Protein Basic Domain Rapidly Translocates through the Plasma Membrane and Accumulates in the Cell Nucleus

1 reference

https://pubmed.ncbi.nlm.nih.gov/13679429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A cytoplasmic inhibitor of the JNK signal transduction pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/13679429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Motoneuron apoptosis is blocked by CEP-1347 (KT 7515), a novel inhibitor of the JNK signaling pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/13679429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Six-hour window of opportunity for calpain inhibition in focal cerebral ischemia in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/13679429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Replacement of mammalian auditory hair cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/13679429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amikacin intoxication induces apoptosis and cell proliferation in rat organ of Corti

1 reference

https://pubmed.ncbi.nlm.nih.gov/13679429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Signal transduction by the c-Jun N-terminal kinase (JNK)--from inflammation to development

1 reference

https://pubmed.ncbi.nlm.nih.gov/13679429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxygen radicals and signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/13679429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptosis of guinea pig cochlear hair cells following chronic aminoglycoside treatment.

1 reference

https://pubmed.ncbi.nlm.nih.gov/13679429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dose-dependent response of vestibular hair cells of guinea pigs following streptomycin ototoxiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/13679429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structural organization of MAP-kinase signaling modules by scaffold proteins in yeast and mammals

1 reference

https://pubmed.ncbi.nlm.nih.gov/13679429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CEP-1347/KT-7515, an inhibitor of c-jun N-terminal kinase activation, attenuates the 1-methyl-4-phenyl tetrahydropyridine-mediated loss of nigrostriatal dopaminergic neurons In vivo.

1 reference

https://pubmed.ncbi.nlm.nih.gov/13679429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.23-24-08596.2003

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:13679429%20AND%20SRC:MED&resulttype=core&format=json

16 December 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:13679429%20AND%20SRC:MED&resulttype=core&format=json

16 December 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:13679429%20AND%20SRC:MED&resulttype=core&format=json

16 December 2019

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