(Q34248342)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16373499%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

title

Inositols prevent and reverse endothelial dysfunction in diabetic rat and rabbit vasculature metabolically and by scavenging superoxide (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16373499%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

0 references

12

1 reference

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Nilberto Robson Falcão do Nascimento

14 January 2020

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16373499%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

Renata S Alves

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16373499%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

Douglas Heimark

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16373499%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

author name string

L M A Lessa

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16373499%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

M R Kerntopf

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16373499%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

C M Sousa

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16373499%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

M G R Queiroz

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16373499%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

J Price

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16373499%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

J Larner

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16373499%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

X Du

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16373499%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

M Brownlee

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16373499%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

C Davis

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16373499%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

M C Fonteles

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16373499%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

language of work or name

English

0 references

publication date

22 December 2005

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16373499%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

14 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16373499%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

volume

103

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16373499%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16373499%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

page(s)

218-223

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16373499%20AND%20SRC:MED&resulttype=core&format=json

Allosteric activation of protein phosphatase 2C by D-chiro-inositol-galactosamine, a putative mediator mimetic of insulin action.

14 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1325005

Inhibition of xanthine oxidase by phytic acid and its antioxidative action

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1325005

Insulin-mediated effect on the activity of UDPG-glycogen transglucosylase of muscle

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1325005

Isolation, structure, synthesis, and bioactivity of a novel putative insulin mediator. A galactosamine chiro-inositol pseudo-disaccharide Mn2+ chelate with insulin-like activity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1325005

Benfotiamine blocks three major pathways of hyperglycemic damage and prevents experimental diabetic retinopathy

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1325005

Both myo-inositol to chiro-inositol epimerase activities and chiro-inositol to myo-inositol ratios are decreased in tissues of GK type 2 diabetic rats compared to Wistar controls

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1325005

Oxygen radicals in cardiovascular-renal disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1325005

D-chiro-inositol--its functional role in insulin action and its deficit in insulin resistance

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1325005

Basal and stimulated protein S-nitrosylation in multiple cell types and tissues

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1325005

Biochemistry and molecular cell biology of diabetic complications

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1325005

D-chiro-inositol in insulin action and insulin resistance-old-fashioned biochemistry still at work

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1325005

Hyperglycemia-induced mitochondrial superoxide overproduction activates the hexosamine pathway and induces plasminogen activator inhibitor-1 expression by increasing Sp1 glycosylation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1325005

Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1325005

Endothelial dysfunction and peroxynitrite formation are early events in angiotensin-induced cardiovascular disorders.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1325005

Ovulatory and metabolic effects of D-chiro-inositol in the polycystic ovary syndrome

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1325005

Phosphoinositol glycan derived mediators and insulin resistance. Prospects for diagnosis and therapy

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1325005

A model phosphatase 2C --> phosphatase 1 activation cascade via dual control of inhibitor-1 (INH-1) and DARPP-32 dephosphorylation by two inositol glycan putative insulin mediators from beef liver

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1325005

Relationship among cholesterol, superoxide anion and endothelium-dependent relaxation in diabetic rats

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1325005

Insulin-mimetic signalling of synthetic phosphoinositolglycans in isolated rat adipocytes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1325005

Convergence and divergence of the signaling pathways for insulin and phosphoinositolglycans.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1325005

Overexpression of glyoxalase-I in bovine endothelial cells inhibits intracellular advanced glycation endproduct formation and prevents hyperglycemia-induced increases in macromolecular endocytosis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1325005

Aminoguanidine and the prevention of leukocyte dysfunction in diabetes mellitus: a direct vital microscopic study

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1325005

Multiple signaling pathways involved in the metabolic effects of insulin

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1325005

Elevated circulating free fatty acid levels impair endothelium-dependent vasodilation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1325005

Phosphoinositolglycan-peptides from yeast potently induce metabolic insulin actions in isolated rat adipocytes, cardiomyocytes, and diaphragms.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1325005

Vascular hypertrophy in experimental diabetes. Role of advanced glycation end products

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1325005

Infusion of pH 2.0 D-chiro-inositol glycan insulin putative mediator normalizes plasma glucose in streptozotocin diabetic rats at a dose equivalent to insulin without inducing hypoglycaemia

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1325005

Oxidative stress and diabetic vascular complications

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1325005

Chiroinositol deficiency and insulin resistance. III. Acute glycogenic and hypoglycemic effects of two inositol phosphoglycan insulin mediators in normal and streptozotocin-diabetic rats in vivo

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1325005

The reaction of no with superoxide

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1325005

chiro-inositol deficiency and insulin resistance: a comparison of the chiro-inositol- and the myo-inositol-containing insulin mediators isolated from urine, hemodialysate, and muscle of control and type II diabetic subjects

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1325005

D-chiro-inositol metabolism in diabetes mellitus

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1325005

Free radicals in diabetic endothelial cell dysfunction

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1325005

Iron-catalyzed hydroxyl radical formation. Stringent requirement for free iron coordination site

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1325005

Phosphatidylinositol-glycan anchors of membrane proteins: potential precursors of insulin mediators

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1325005

Insulin mediators: structure and formation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1325005

Impaired neurogenic and endothelium-mediated relaxation of penile smooth muscle from diabetic men with impotence

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1325005

Low urinary chiro-inositol excretion in non-insulin-dependent diabetes mellitus

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1325005

Elevated glucose impairs endothelium-dependent relaxation by activating protein kinase C.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1325005

Role of oxidative stress in development of complications in diabetes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1325005

Endothelium-dependent relaxation and noradrenaline sensitivity in mesenteric resistance arteries of streptozotocin-induced diabetic rats

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1325005

Isolation and partial characterisation of insulin-mimetic inositol phosphoglycans from human liver.

6 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0509779103

Chiroinositol deficiency and insulin resistance. I. Urinary excretion rate of chiroinositol is directly associated with insulin resistance in spontaneously diabetic rhesus monkeys.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0509779103

Urinary chiro-inositol excretion is an index marker of insulin sensitivity in Japanese type II diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0509779103

Endothelial dysfunction and metabolic control in streptozotocin-induced diabetic rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0509779103

The SOD mimetic tempol restores vasodilation in afferent arterioles of experimental diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0509779103

Superoxide dismutase: the balance between prevention and induction of oxidative damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0509779103

Determination of transport stoichiometry for two cation-coupled myo-inositol cotransporters: SMIT2 and HMIT.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0509779103

Identification of a novel Na+/myo-inositol cotransporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0509779103

Diabetes, microvascular complications, and cardiovascular complications: what is it about glucose?

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0509779103

The determination of nitrotyrosine residues in proteins

21 January 2018

1 reference

12 December 2020

Plasma nitric oxide concentrations are elevated in insulin-resistant healthy subjects

1 reference

12 December 2020

A putative mediator of insulin action which inhibits adenylate cyclase and adenosine 3',5'-monophosphate-dependent protein kinase: partial purification from rat liver: site and kinetic mechanism of action

1 reference

12 December 2020

Alterations in free radical tissue-defense mechanisms in streptozocin-induced diabetes in rat. Effects of insulin treatment

1 reference

12 December 2020

Phytic acid. A natural antioxidant

1 reference

12 December 2020

Release of intact endothelium-derived relaxing factor depends on endothelial superoxide dismutase activity

1 reference

12 December 2020

Superoxide dismutase recovers altered endothelium-dependent relaxation in diabetic rat aorta

1 reference

12 December 2020

Structural and functional origins of suppressed acetylcholine vasodilation in diabetic rat intestinal arterioles

1 reference

12 December 2020

Chiroinositol deficiency and insulin resistance. II. Acute effects of D-chiroinositol administration in streptozotocin-diabetic rats, normal rats given a glucose load, and spontaneously insulin-resistant rhesus monkeys

1 reference

12 December 2020

Diabetes-associated mesenteric vascular hypertrophy is attenuated by angiotensin-converting enzyme inhibition

1 reference

12 December 2020

Superoxide dismutase restores the influence of nitric oxide on renal arterioles in diabetes mellitus

1 reference

12 December 2020

Transient triglyceridemia decreases vascular reactivity in young, healthy men without risk factors for coronary heart disease

1 reference

12 December 2020

Enhanced, unaltered and impaired nitric oxide-mediated endothelium-dependent relaxation in experimental diabetes mellitus: importance of disease duration

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0509779103

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16373499%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16373499%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

1 reference