(Q34248380)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22260426%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

title

The kynurenine pathway and quinolinic acid: pivotal roles in HIV associated neurocognitive disorders (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22260426%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22260426%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

author name string

Apsara Kandanearatchi

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22260426%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

language of work or name

English

0 references

publication date

27 March 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22260426%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22260426%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

volume

279

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22260426%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

issue

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22260426%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

page(s)

1366-1374

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22260426%20AND%20SRC:MED&resulttype=core&format=json

Neurological complications of HIV infection.

20 January 2020

cites work

1 reference

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Updated research nosology for HIV-associated neurocognitive disorders

21 January 2018

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Variable benefit in neuropsychological function in HIV-infected HAART-treated patients.

21 January 2018

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Prevalence of non-confounded HIV-associated neurocognitive impairment in the context of plasma HIV RNA suppression.

21 January 2018

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Benefit or toxicity from neurologically targeted antiretroviral therapy?

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AIDS dementia complex and HIV-1 brain infection: clinical-virological correlations

21 January 2018

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Immunocytochemical quantitation of human immunodeficiency virus in the brain: correlations with dementia

21 January 2018

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21 January 2018

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Effects of central nervous system antiretroviral penetration on cognitive functioning in the ALLRT cohort

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Lost in translation: again, another failed neuroprotection trial.

21 January 2018

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Characterization of monocyte maturation/differentiation that facilitates their transmigration across the blood-brain barrier and infection by HIV: implications for NeuroAIDS.

21 January 2018

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21 January 2018

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Varied tropism of HIV-1 isolates derived from different regions of adult brain cortex discriminate between patients with and without AIDS dementia complex (ADC): evidence for neurotropic HIV variants.

21 January 2018

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21 January 2018

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HIV-1 associated dementia: update on pathological mechanisms and therapeutic approaches

21 January 2018

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Molecular and cellular mechanisms of neuronal cell death in HIV dementia

21 January 2018

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Disruption of neuronal autophagy by infected microglia results in neurodegeneration

21 January 2018

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Persistent hijacking of brain proteasomes in HIV-associated dementia

21 January 2018

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Extensive astrocyte infection is prominent in human immunodeficiency virus-associated dementia

21 January 2018

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Pathways to neuronal injury and apoptosis in HIV-associated dementia.

21 January 2018

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Gene expression profiles of HIV-1-infected glia and brain: toward better understanding of the role of astrocytes in HIV-1-associated neurocognitive disorders

21 January 2018

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Long-term HIV-1 infection of neural progenitor populations

21 January 2018

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HIV/gp120 decreases adult neural progenitor cell proliferation via checkpoint kinase-mediated cell-cycle withdrawal and G1 arrest

21 January 2018

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Cliniconeuropathologic correlates of human immunodeficiency virus in the era of antiretroviral therapy

21 January 2018

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21 January 2018

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The relationship between ApoE, TNFA, IL1a, IL1b and IL12b genes and HIV-1-associated dementia.

21 January 2018

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HIV-1 infection and AIDS dementia are influenced by a mutant MCP-1 allele linked to increased monocyte infiltration of tissues and MCP-1 levels

21 January 2018

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Macrophage tropism of human immunodeficiency virus type 1 isolates from brain and lymphoid tissues predicts neurotropism independent of coreceptor specificity

21 January 2018

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Genetic attributes of cerebrospinal fluid-derived HIV-1 env.

21 January 2018

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Genetic and functional analysis of full-length human immunodeficiency virus type 1 env genes derived from brain and blood of patients with AIDS.

21 January 2018

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Interaction between CCAAT/enhancer binding protein and cyclic AMP response element binding protein 1 regulates human immunodeficiency virus type 1 transcription in cells of the monocyte/macrophage lineage.

21 January 2018

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Tryptophan, Neurodegeneration and HIV-Associated Neurocognitive Disorder

21 January 2018

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Quinolinic acid is produced by macrophages stimulated by platelet activating factor, Nef and Tat.

21 January 2018

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Expression of the kynurenine pathway enzymes in human microglia and macrophages

21 January 2018

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Expression of indoleamine 2,3-dioxygenase and production of quinolinic acid by human microglia, astrocytes, and neurons

21 January 2018

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Kynurenine pathway metabolism in human astrocytes: a paradox for neuronal protection

21 January 2018

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Kynurenine pathway metabolism in human blood-brain-barrier cells: implications for immune tolerance and neurotoxicity.

21 January 2018

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Kynurenine is an endothelium-derived relaxing factor produced during inflammation

21 January 2018

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Prevention of allogeneic fetal rejection by tryptophan catabolism

21 January 2018

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Potential regulatory function of human dendritic cells expressing indoleamine 2,3-dioxygenase

21 January 2018

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Tryptophan-derived catabolites are responsible for inhibition of T and natural killer cell proliferation induced by indoleamine 2,3-dioxygenase.

21 January 2018

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21 January 2018

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Quinolinic acid in cerebrospinal fluid and serum in HIV-1 infection: relationship to clinical and neurological status

21 January 2018

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CSF quinolinic acid levels are determined by local HIV infection: cross-sectional analysis and modelling of dynamics following antiretroviral therapy.

21 January 2018

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Elevated cerebrospinal fluid quinolinic acid levels are associated with region-specific cerebral volume loss in HIV infection

21 January 2018

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Quantitation of human immunodeficiency virus, immune activation factors, and quinolinic acid in AIDS brains

21 January 2018

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Frontal cortex indoleamine-2,3-dioxygenase activity is increased in HIV-1-associated dementia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08500.X

Chronic exposure of human neurons to quinolinic acid results in neuronal changes consistent with AIDS dementia complex.

21 January 2018

1 reference

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Relationship of neurologic status in macaques infected with the simian immunodeficiency virus to cerebrospinal fluid quinolinic acid and kynurenic acid

21 January 2018

1 reference

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Prolonged exposure to submicromolar concentrations of quinolinic acid causes excitotoxic damage in organotypic cultures of rat corticostriatal system

21 January 2018

1 reference

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Kynurenine pathway inhibition reduces neurotoxicity of HIV-1-infected macrophages.

21 January 2018

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Combined effect of antiretroviral therapy and blockade of IDO in SIV-infected rhesus macaques

21 January 2018

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Characterisation of the expression of NMDA receptors in human astrocytes

21 January 2018

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Mechanism for quinolinic acid cytotoxicity in human astrocytes and neurons.

21 January 2018

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Effect of quinolinic acid on human astrocytes morphology and functions: implications in Alzheimer's disease.

21 January 2018

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Interferon-γ regulates the proliferation and differentiation of mesenchymal stem cells via activation of indoleamine 2,3 dioxygenase (IDO).

21 January 2018

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Induction of indolamine 2,3-dioxygenase in primary human macrophages by human immunodeficiency virus type 1 is strain dependent

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2012.08500.X

Quinolinic acid upregulates chemokine production and chemokine receptor expression in astrocytes

21 January 2018

1 reference

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