(Q34250544)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25204558%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

title

Central but not systemic administration of XPro1595 is therapeutic following moderate spinal cord injury in mice (English)

1 reference

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16 February 2020

4

1 reference

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16 February 2020

Minna Yli-Karjanmaa

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25204558%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

David E. Szymkowski

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25204558%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Kate Lykke Lambertsen

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25204558%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

author name string

Hans G Novrup

1

1 reference

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16 February 2020

Valerie Bracchi-Ricard

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25204558%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Ditte G Ellman

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25204558%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Anjana Jain

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25204558%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Erik Runko

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25204558%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Lise Lyck

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25204558%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Damien D Pearse

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25204558%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

John R Bethea

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25204558%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

publication date

10 September 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25204558%20AND%20SRC:MED&resulttype=core&format=json

Journal of Neuroinflammation

16 February 2020

published in

1 reference

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16 February 2020

volume

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25204558%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

page(s)

159

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25204558%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 4.0 International

16 February 2020

copyright license

start time

10 September 2014

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

exact match

https://scigraph.springernature.com/pub.10.1186/s12974-014-0159-6

0 references

cites work

Depression and anxiety in adolescents with pediatric-onset spinal cord injury

1 reference

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Knockdown of interleukin-1 receptor type-1 on endothelial cells attenuated stress-induced neuroinflammation and prevented anxiety-like behavior.

6 July 2018

1 reference

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Astrocyte-specific activation of TNFR2 promotes oligodendrocyte maturation by secretion of leukemia inhibitory factor

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4176557

Inhibition of NADPH oxidase activation in oligodendrocytes reduces cytotoxicity following trauma

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4176557

Inhibition of astroglial NF-κB enhances oligodendrogenesis following spinal cord injury.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4176557

Functional analyses of TNFR2 in physiological and pathological retina angiogenesis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4176557

Genetic KCa3.1-deficiency produces locomotor hyperactivity and alterations in cerebral monoamine levels

6 July 2018

1 reference

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Inflammatory cytokines in experimental and human stroke.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4176557

A TNF receptor 2 selective agonist rescues human neurons from oxidative stress-induced cell death

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4176557

Inflammation and axon regeneration

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4176557

Inhibition of soluble tumour necrosis factor is therapeutic in experimental autoimmune encephalomyelitis and promotes axon preservation and remyelination

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4176557

Tumor necrosis factor alpha (TNF-α), anti-TNF-α and demyelination revisited: an ongoing story

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4176557

Identification of two distinct macrophage subsets with divergent effects causing either neurotoxicity or regeneration in the injured mouse spinal cord

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4176557

Anti-TNF biologic agents: still the therapy of choice for rheumatoid arthritis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4176557

Iron is essential for oligodendrocyte genesis following intraspinal macrophage activation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4176557

Inhibition of soluble TNF signaling in a mouse model of Alzheimer's disease prevents pre-plaque amyloid-associated neuropathology

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4176557

Cell death after spinal cord injury is exacerbated by rapid TNF alpha-induced trafficking of GluR2-lacking AMPARs to the plasma membrane

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4176557

Interleukin-1beta and tumor necrosis factor-alpha are expressed by different subsets of microglia and macrophages after ischemic stroke in mice

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4176557

TNF signaling inhibition in the CNS: implications for normal brain function and neurodegenerative disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4176557

Intranigral lentiviral delivery of dominant-negative TNF attenuates neurodegeneration and behavioral deficits in hemiparkinsonian rats

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4176557

Oligodendrocyte generation is differentially influenced by toll-like receptor (TLR) 2 and TLR4-mediated intraspinal macrophage activation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4176557

Social and environmental enrichment improves sensory and motor recovery after severe contusive spinal cord injury in the rat.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4176557

Axonal lesion-induced microglial proliferation and microglial cluster formation in the mouse.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4176557

Inflammation and its role in neuroprotection, axonal regeneration and functional recovery after spinal cord injury

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4176557

Dominant-negative inhibitors of soluble TNF attenuate experimental arthritis without suppressing innate immunity to infection

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4176557

Blocking soluble tumor necrosis factor signaling with dominant-negative tumor necrosis factor inhibitor attenuates loss of dopaminergic neurons in models of Parkinson's disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4176557

TNFalpha signaling in depression and anxiety: behavioral consequences of individual receptor targeting

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4176557

Etanercept and clinical outcomes, fatigue, and depression in psoriasis: double-blind placebo-controlled randomised phase III trial.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4176557

Comparative analysis of lesion development and intraspinal inflammation in four strains of mice following spinal contusion injury

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4176557

Inhibition of astroglial nuclear factor kappaB reduces inflammation and improves functional recovery after spinal cord injury

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4176557

Inactivation of TNF signaling by rationally designed dominant-negative TNF variants

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4176557

6 July 2018

Etanercept: An overview

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4176557

Listeria monocytogenes infection as a complication of treatment with tumor necrosis factor alpha-neutralizing agents

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4176557

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4176557

Systemically administered interleukin-10 reduces tumor necrosis factor-alpha production and significantly improves functional recovery following traumatic spinal cord injury in rats

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4176557

Depletion of hematogenous macrophages promotes partial hindlimb recovery and neuroanatomical repair after experimental spinal cord injury

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4176557

Damage control in the nervous system: beware the immune system in spinal cord injury.

6 July 2018

1 reference

https://api.crossref.org/works/10.1186%2FS12974-014-0159-6

Microglia protect neurons against ischemia by synthesis of tumor necrosis factor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS12974-014-0159-6

Transmembrane tumour necrosis factor is neuroprotective and regulates experimental autoimmune encephalomyelitis via neuronal nuclear factor-kappaB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS12974-014-0159-6

TNF alpha promotes proliferation of oligodendrocyte progenitors and remyelination.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS12974-014-0159-6

Divergent roles for p55 and p75 tumor necrosis factor receptors in the pathogenesis of MOG(35-55)-induced experimental autoimmune encephalomyelitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS12974-014-0159-6

Transmembrane TNF protects mutant mice against intracellular bacterial infections, chronic inflammation and autoimmunity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS12974-014-0159-6

Chronic dim light at night provokes reversible depression-like phenotype: possible role for TNF.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS12974-014-0159-6

Blockage of immune-mediated inner ear damage by etanercept

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS12974-014-0159-6

Proinflammatory cytokine synthesis in the injured mouse spinal cord: multiphasic expression pattern and identification of the cell types involved.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS12974-014-0159-6

Basso Mouse Scale for locomotion detects differences in recovery after spinal cord injury in five common mouse strains.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS12974-014-0159-6

Assessing behavioural function following a pyramidotomy lesion of the corticospinal tract in adult mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS12974-014-0159-6

Cortical and subcortical lesions impair skilled walking in the ladder rung walking test: a new task to evaluate fore- and hindlimb stepping, placing, and co-ordination

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS12974-014-0159-6

Microglial-macrophage synthesis of tumor necrosis factor after focal cerebral ischemia in mice is strain dependent.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS12974-014-0159-6

Astrocytes play a key role in EAE pathophysiology by orchestrating in the CNS the inflammatory response of resident and peripheral immune cells and by suppressing remyelination

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS12974-014-0159-6

Tumor necrosis factor-alpha induces cFOS and strongly potentiates glutamate-mediated cell death in the rat spinal cord

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS12974-014-0159-6

Analysis of cognition, motor performance and anxiety in young and aged tumor necrosis factor alpha receptor 1 and 2 deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS12974-014-0159-6

Infliximab, a TNF-α antagonist treatment in patients with ankylosing spondylitis: the impact on depression, anxiety and quality of life level

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS12974-014-0159-6

Symptoms of depression over time in adults with pediatric-onset spinal cord injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS12974-014-0159-6

Granulomatous infectious diseases associated with tumor necrosis factor antagonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS12974-014-0159-6

Production of tumor necrosis factor in spinal cord following traumatic injury in rats

21 January 2018

1 reference

12 December 2020

Tumor necrosis factor receptor deletion reduces nuclear factor-kappaB activation, cellular inhibitor of apoptosis protein 2 expression, and functional recovery after traumatic spinal cord injury

1 reference

12 December 2020

Sequential expression of c-fos protooncogene, TNF-alpha, and dynorphin genes in spinal cord following experimental traumatic injury

1 reference

12 December 2020

Severity of symptoms and demyelination in MOG-induced EAE depends on TNFR1

1 reference

12 December 2020

10.1186/S12974-014-0159-6

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25204558%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

16 February 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25204558%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25204558%20AND%20SRC:MED&resulttype=core&format=json