(Q34251031)

31 July 2017

Zinc dyshomeostasis is linked with the loss of mucolipidosis IV-associated TRPML1 ion channel (English)

1 reference

31 July 2017

Jonathan L Eichelsdoerfer

1

1 reference

31 July 2017

Jeffrey A Evans

2

1 reference

31 July 2017

Susan A Slaugenhaupt

3

1 reference

31 July 2017

Math P Cuajungco

4

1 reference

31 July 2017

language of work or name

English

0 references

publication date

23 September 2010

1 reference

Journal of Biological Chemistry

31 July 2017

1 reference

31 July 2017

285

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31 July 2017

34304-34308

1 reference

31 July 2017

45

1 reference

Small molecule activators of TRPML3

31 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2966043

The tissue-specific expression of TRPML2 (MCOLN-2) gene is influenced by the presence of TRPML1.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2966043

Mucolipidosis type IV: the effect of increased lysosomal pH on the abnormal lysosomal storage.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2966043

Ethambutol-induced toxicity is mediated by zinc and lysosomal membrane permeabilization in cultured retinal cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2966043

The type IV mucolipidosis-associated protein TRPML1 is an endolysosomal iron release channel

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2966043

Autophagic dysfunction in mucolipidosis type IV patients

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2966043

Membrane traffic and turnover in TRP-ML1-deficient cells: a revised model for mucolipidosis type IV pathogenesis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2966043

A helix-breaking mutation in TRPML3 leads to constitutive activity underlying deafness in the varitint-waddler mouse

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2966043

Activating mutation in a mucolipin transient receptor potential channel leads to melanocyte loss in varitint-waddler mice.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2966043

Zinc transporter 2 (SLC30A2) can suppress the vesicular zinc defect of adaptor protein 3-depleted fibroblasts by promoting zinc accumulation in lysosomes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2966043

TRP-ML1 regulates lysosomal pH and acidic lysosomal lipid hydrolytic activity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2966043

The neurobiology of zinc in health and disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2966043

Electron microscopy of degenerative changes in the chick basilar papilla after gentamicin exposure

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2966043

Modulation of mitochondrial function by endogenous Zn2+ pools.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2966043

Nitric oxide generators produce accumulation of chelatable zinc in hippocampal neuronal perikarya.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2966043

6 July 2018

Zinc and brain injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2966043

Measurement of intracellular free zinc in living cortical neurons: routes of entry.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2966043

Zinc metabolism in the brain: relevance to human neurodegenerative disorders

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2966043

Stimulation-induced uptake and release of zinc in hippocampal slices

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2966043

Zinc neurotoxicity in cortical cell culture

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2966043

Neurobiology of zinc and zinc-containing neurons

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2966043

Mucolipidosis type IV: clinical spectrum and natural history.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2966043

Zinc and 4-hydroxy-2-nonenal mediate lysosomal membrane permeabilization induced by H2O2 in cultured hippocampal neurons.

6 July 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C110.165480

Oxidative injury triggers autophagy in astrocytes: the role of endogenous zinc

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C110.165480

Mitochondrial aberrations in mucolipidosis Type IV.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C110.165480

Chaperone-mediated autophagy is defective in mucolipidosis type IV.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C110.165480

Enhanced zinc consumption causes memory deficits and increased brain levels of zinc.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C110.165480

The effects of enhanced zinc on spatial memory and plaque formation in transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C110.165480

Long-term intake of a high zinc diet causes iron deficiency anemia accompanied by reticulocytosis and extra-medullary erythropoiesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C110.165480

Ethambutol-induced vacuolar changes and neuronal loss in rat retinal cell culture: mediation by endogenous zinc

21 January 2018

1 reference

12 December 2020

Measuring zinc in living cells. A new generation of sensitive and selective fluorescent probes

1 reference

12 December 2020

A quinoline fluorescence method for visualizing and assaying the histochemically reactive zinc (bouton zinc) in the brain

1 reference

12 December 2020

A potentially dynamic lysosomal role for the endogenous TRPML proteins

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.C110.165480

1 reference

31 July 2017

1 reference

31 July 2017

1 reference