(Q34251420)

31 July 2017

title

Accelerating cocaine metabolism as an approach to the treatment of cocaine abuse and toxicity (English)

1 reference

31 July 2017

1 reference

Charles W Schindler

1

1 reference

31 July 2017

Steven R Goldberg

series ordinal

2

1 reference

31 July 2017

language of work or name

1 reference

1 February 2012

1 reference

Future Medicinal Chemistry

31 July 2017

published in

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31 July 2017

volume

4

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31 July 2017

issue

2

1 reference

31 July 2017

page(s)

163-175

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Modification of pharmacokinetic and abuse-related effects of cocaine by human-derived cocaine hydrolase in monkeys

31 July 2017

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6 July 2018

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6 July 2018

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6 July 2018

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Gene-delivered butyrylcholinesterase is prophylactic against the toxicity of chemical warfare nerve agents and organophosphorus compounds

6 July 2018

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6 July 2018

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Design, preparation, and characterization of high-activity mutants of human butyrylcholinesterase specific for detoxification of cocaine.

6 July 2018

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Anti-cocaine vaccine development

6 July 2018

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6 July 2018

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Structural analysis of thermostabilizing mutations of cocaine esterase

6 July 2018

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The concept of pharmacologic cocaine interception as a treatment for drug abuse

6 July 2018

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Review of treatment for cocaine dependence

6 July 2018

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A Thermally Stable Form of Bacterial Cocaine Esterase: A Potential Therapeutic Agent for Treatment of Cocaine Abuse

6 July 2018

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Characterization of a high-activity mutant of human butyrylcholinesterase against (-)-cocaine

6 July 2018

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Cocaine-specific antibodies blunt the subjective effects of smoked cocaine in humans

6 July 2018

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Cocaine vaccine for the treatment of cocaine dependence in methadone-maintained patients: a randomized, double-blind, placebo-controlled efficacy trial

6 July 2018

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Prevention and reversal by cocaine esterase of cocaine-induced cardiovascular effects in rats

6 July 2018

1 reference

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Cocaine esterase prevents cocaine-induced toxicity and the ongoing intravenous self-administration of cocaine in rats

6 July 2018

1 reference

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Lasting reduction of cocaine action in neostriatum--a hydrolase gene therapy approach

6 July 2018

1 reference

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Effects of cocaine esterase following its repeated administration with cocaine in mice

6 July 2018

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The effect of a chimeric human/murine anti-cocaine monoclonal antibody on cocaine self-administration in rats

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293209

A bacterial cocaine esterase protects against cocaine-induced epileptogenic activity and lethality

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293209

Most efficient cocaine hydrolase designed by virtual screening of transition states

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293209

An albumin-butyrylcholinesterase for cocaine toxicity and addiction: catalytic and pharmacokinetic properties

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293209

A cocaine hydrolase engineered from human butyrylcholinesterase selectively blocks cocaine toxicity and reinstatement of drug seeking in rats.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293209

New treatments for cocaine dependence: a focused review

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293209

Recombinant human butyrylcholinesterase from milk of transgenic animals to protect against organophosphate poisoning

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293209

Identification and characterization of single chain anti-cocaine catalytic antibodies

6 July 2018

1 reference

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LARGE SCALE PURIFICATION OF BUTYRYLCHOLINESTERASE FROM HUMAN PLASMA SUITABLE FOR INJECTION INTO MONKEYS; A POTENTIAL NEW THERAPEUTIC FOR PROTECTION AGAINST COCAINE AND NERVE AGENT TOXICITY.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293209

Viral transduction of cocaine hydrolase in brain reward centers

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293209

Toward cocaine esterase therapeutics

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293209

Biochemical characterization and structural analysis of a highly proficient cocaine esterase

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293209

Synthesis, properties, and reactivity of cocaine benzoylthio ester possessing the cocaine absolute configuration

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293209

Crystal structure of a bacterial cocaine esterase

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293209

Cocaine catalytic antibodies: the primary importance of linker effects

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293209

Predicted Michaelis-Menten complexes of cocaine-butyrylcholinesterase. Engineering effective butyrylcholinesterase mutants for cocaine detoxication

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293209

Cocaine vaccines: antibody protection against relapse in a rat model

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293209

Gene cloning and nucleotide sequencing and properties of a cocaine esterase from Rhodococcus sp. strain MB1

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293209

Attenuation of cocaine-induced locomotor activity by butyrylcholinesterase.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293209

A catalytic antibody against cocaine prevents cocaine's reinforcing and toxic effects in rats

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293209

The influence of plasma butyrylcholinesterase concentration on the in vitro hydrolysis of cocaine in human plasma

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293209

Enhancing cocaine metabolism with butyrylcholinesterase as a treatment strategy

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293209

Cocaine detoxification by human plasma butyrylcholinesterase.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293209

Cocaine and butyrylcholinesterase (BChE): determination of enzymatic parameters

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293209

Medical complications of cocaine: possible relationship to low plasma cholinesterase enzyme

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293209

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293209

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293209

Cocaine complications and pseudocholinesterase.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293209

Enzymes as pretreatment drugs for organophosphate toxicity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293209

Prolongation of cocaine effect.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293209

Association between life-threatening cocaine toxicity and plasma cholinesterase activity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293209

Metabolism of cocaine in man

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293209

Cocaine and succinylcholine sensitivity: a new caution

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293209

Hydrolysis of cocaine in human plasma by cholinesterase

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293209

Efficacy of a therapeutic cocaine vaccine in rodent models.

6 July 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.11.181

Evaluation of anti-cocaine antibodies and a cocaine vaccine in a rat self-administration model.

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.11.181

Human therapeutic cocaine vaccine: safety and immunogenicity

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.11.181

A chimeric human/murine anticocaine monoclonal antibody inhibits the distribution of cocaine to the brain in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.11.181

Pharmacokinetic approaches to treatment of drug addiction.

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.11.181

Plasma butyrylcholinesterase activity and cocaine half-life differ significantly in rhesus and squirrel monkeys.

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.11.181

Administration of purified human plasma cholinesterase protects against cocaine toxicity in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.11.181

Increased hepatotoxicity and cardiac fibrosis in cocaine-treated butyrylcholinesterase knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.11.181

Effect of cocaine metabolites on behavior: possible neuroendocrine mechanisms.

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.11.181

Antibody-catalyzed degradation of cocaine.

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.11.181

A catalytic antibody against cocaine attenuates cocaine's cardiovascular effects in mice: a dose and time course analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.11.181

Substrate-assisted antibody catalysis

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.11.181

Complete reaction cycle of a cocaine catalytic antibody at atomic resolution.

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.11.181

Butyrylcholinesterase and acetylcholinesterase prophylaxis against soman poisoning in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.11.181

Prevention of soman-induced cognitive deficits by pretreatment with human butyrylcholinesterase in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.11.181

Therapeutic use of butyrylcholinesterase for cocaine intoxication.

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.11.181

Intravenous butyrylcholinesterase administration and plasma and brain levels of cocaine and metabolites in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.11.181

Characterization of butyrylcholinesterase antagonism of cocaine-induced hyperactivity

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.11.181

Wild-type and A328W mutant human butyrylcholinesterase tetramers expressed in Chinese hamster ovary cells have a 16-hour half-life in the circulation and protect mice from cocaine toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.11.181

Re-engineering butyrylcholinesterase as a cocaine hydrolase

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.11.181

Cocaine metabolism accelerated by a re-engineered human butyrylcholinesterase

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.11.181

An engineered cocaine hydrolase blunts and reverses cardiovascular responses to cocaine in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.11.181

Gene transfer of cocaine hydrolase suppresses cardiovascular responses to cocaine in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.11.181

Rapid and robust protection against cocaine-induced lethality in rats by the bacterial cocaine esterase.

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.11.181

Cocaine esterase: interactions with cocaine and immune responses in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.11.181

Peripheral cocaine-blocking agents: new medications for cocaine dependence. An introduction to immunological and enzymatic approaches to treating cocaine dependence reported by Fox, Gorelick and Cohen in the immediately succeeding articles (see page

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.11.181

Safety of administration of human butyrylcholinesterase and its conjugates with soman or VX in rats

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293209

Natural and artificial enzymes against cocaine. I. Monoclonal antibody 15A10 and the reinforcing effects of cocaine in rats.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293209

Catalytic antibodies that hydrolyze (-)-cocaine obtained by a high-throughput procedure.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293209

Butyrylcholinesterase accelerates cocaine metabolism: in vitro and in vivo effects in nonhuman primates and humans.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293209

An improved cocaine hydrolase: the A328Y mutant of human butyrylcholinesterase is 4-fold more efficient.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293209

Effects of dopamine D-1 and D-2 antagonists on cocaine self-administration under different schedules of reinforcement in the rat.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293209

Use of cholinesterases as pretreatment drugs for the protection of rhesus monkeys against soman toxicity

28 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22300096

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.4155/FMC.11.181

1 reference

31 July 2017

1 reference

31 July 2017

1 reference