(Q34253323)

31 July 2017

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title

Homocysteine is transported by the microvillous plasma membrane of human placenta (English)

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31 July 2017

Eleni Tsitsiou

1

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31 July 2017

Colin P Sibley

2

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31 July 2017

Stephen W D'Souza

3

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31 July 2017

Otilia Catanescu

4

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31 July 2017

Donald W Jacobsen

5

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31 July 2017

Jocelyn D Glazier

6

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31 July 2017

publication date

22 June 2010

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Journal of Inherited Metabolic Disease

31 July 2017

published in

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31 July 2017

volume

34

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31 July 2017

issue

1

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31 July 2017

page(s)

57-65

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Expression of folate transporters in human placenta and implications for homocysteine metabolism

31 July 2017

cites work

1 reference

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6 July 2018

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The SNAT4 isoform of the system A amino acid transporter is functional in human placental microvillous plasma membrane

6 July 2018

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Placental folate transport during pregnancy

6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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Identification of LAT4, a novel amino acid transporter with system L activity

6 July 2018

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Regulation of reduced-folate transporter-1 (RFT-1) by homocysteine and identity of transport systems for homocysteine uptake in retinal pigment epithelial (RPE) cells

6 July 2018

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Characterization of cationic amino acid transporters and expression of endothelial nitric oxide synthase in human placental microvascular endothelial cells

6 July 2018

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Changes in haemostasis during normal pregnancy: does homocysteine play a role in maintaining homeostasis?

6 July 2018

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L-Arginine transport across the basal plasma membrane of the syncytiotrophoblast of the human placenta from normal and preeclamptic pregnancies

6 July 2018

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Sodium-coupled neutral amino acid (System N/A) transporters of the SLC38 gene family

6 July 2018

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Homocysteine, folic acid and B-group vitamins in obstetrics and gynaecology

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2966547

Increased nitric oxide synthesis in uraemic platelets is dependent on L-arginine transport via system y(+)L.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2966547

System L: heteromeric exchangers of large, neutral amino acids involved in directional transport

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2966547

Glucose transport and system A activity in syncytiotrophoblast microvillous and basal plasma membranes in intrauterine growth restriction

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2966547

Activation of system L heterodimeric amino acid exchangers by intracellular substrates

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2966547

Expression and regulation of 4F2hc and hLAT1 in human trophoblasts

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2966547

Folate, vitamin B12 and homocysteine in relation to birth defects and pregnancy outcome.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2966547

Evidence for the transport of neutral as well as cationic amino acids by ATA3, a novel and liver-specific subtype of amino acid transport system A

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2966547

Characterisation of L-tryptophan transporters in human placenta: a comparison of brush border and basal membrane vesicles

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2966547

Amino acid transporters in the human placenta

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2966547

Targeted disruption of the methionine synthase gene in mice

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2966547

Homocysteine inhibits retinoic acid synthesis: a mechanism for homocysteine-induced congenital defects

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2966547

Primary structure, functional characteristics and tissue expression pattern of human ATA2, a subtype of amino acid transport system A

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2966547

The heterodimeric amino acid transporter 4F2hc/y+LAT2 mediates arginine efflux in exchange with glutamine

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2966547

Cloning and functional expression of ATA1, a subtype of amino acid transporter A, from human placenta

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2966547

Development and polarization of cationic amino acid transporters and regulators in the human placenta

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2966547

LAT2, a new basolateral 4F2hc/CD98-associated amino acid transporter of kidney and intestine

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2966547

Folic acid and homocyst(e)ine metabolic defects and the risk of placental abruption, pre-eclampsia and spontaneous pregnancy loss: A systematic review

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2966547

6 July 2018

Homocysteine metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2966547

Identification of a membrane protein, LAT-2, that Co-expresses with 4F2 heavy chain, an L-type amino acid transport activity with broad specificity for small and large zwitterionic amino acids

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2966547

Amino acid transport of y+L-type by heterodimers of 4F2hc/CD98 and members of the glycoprotein-associated amino acid transporter family

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2966547

Expression cloning and characterization of a transporter for large neutral amino acids activated by the heavy chain of 4F2 antigen (CD98)

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2966547

The metabolism of homocysteine: pathways and regulation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2966547

System y+L: the broad scope and cation modulated amino acid transporter

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2966547

Transporters for cationic amino acids in animal cells: discovery, structure, and function

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2966547

Homocysteine and cardiovascular disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2966547

Nitric oxide and pregnancy

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2966547

Membrane potential difference and intracellular cation concentrations in human placental trophoblast cells in culture

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2966547

Not trophoblast alone: a review of the contribution of the fetal microvasculature to transplacental exchange

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2966547

Development of Mammalian Sulfur Metabolism: Absence of Cystathionase in Human Fetal Tissues

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2966547

Characterization of tryptophan transport in human placental brush-border membrane vesicles

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2966547

Homocysteine uptake by human umbilical vein endothelial cells in culture

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2966547

Prevention of neural tube defects: results of the Medical Research Council Vitamin Study. MRC Vitamin Study Research Group

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2966547

Homocysteine induces trophoblast cell death with apoptotic features.

6 July 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-010-9141-3

Effect of folic acid on homocysteine-induced trophoblast apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-010-9141-3

Extracellular concentration of homocysteine in human cell lines is influenced by specific inhibitors of cyst(e)ine transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-010-9141-3

Novel mechanism causing restricted fetal growth: does maternal homocysteine impair placental amino acid transport?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-010-9141-3

Folic acid uptake by the human syncytiotrophoblast: interference by pharmacotherapy, drugs of abuse and pathological conditions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-010-9141-3

Effect of folate deficiency on placental DNA methylation in hyperhomocysteinemic rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-010-9141-3

Effects of homocysteine on l-arginine transport and nitric oxide formation in human platelets

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-010-9141-3

L-serine uptake by human placental microvillous membrane vesicles.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-010-9141-3

Maternal and fetal plasma homocysteine concentrations at birth: the influence of folate, vitamin B12, and the 5,10-methylenetetrahydrofolate reductase 677C-->T variant.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-010-9141-3

Maternal homocysteine before conception and throughout pregnancy predicts fetal homocysteine and birth weight

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-010-9141-3

Homocysteine-induced inhibition of nitric oxide production in platelets: a study on healthy and diabetic subjects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-010-9141-3

Methylenetetrahydrofolate reductase deficiency and low dietary folate increase embryonic delay and placental abnormalities in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-010-9141-3

Autonomic nerve trauma at radical hysterectomy: the nerve content and subtypes within the superficial and deep uterosacral ligaments.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-010-9141-3

Homocysteine transport by systems L, A and y+L across the microvillous plasma membrane of human placenta.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-010-9141-3

Modification of fetal plasma amino acid composition by placental amino acid exchangers in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-010-9141-3

In vitro methods for studying human placental amino acid transport placental villous fragments.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2966547

In vitro methods for studying human placental amino acid transport: placental plasma membrane vesicles.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2966547

Maternal total homocysteine concentration and neonatal size in India.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2966547

The pregnancy-related decrease in fasting plasma homocysteine is not explained by folic acid supplementation, hemodilution, or a decrease in albumin in a longitudinal study.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2966547

Plasma total homocysteine, pregnancy complications, and adverse pregnancy outcomes: the Hordaland Homocysteine study

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2966547

Homocyst(e)ine decreases bioavailable nitric oxide by a mechanism involving glutathione peroxidase

28 October 2018

1 reference

12 December 2020

The relationship between maternal and neonatal umbilical cord plasma homocyst(e)ine suggests a potential role for maternal homocyst(e)ine in fetal metabolism

1 reference

12 December 2020

Neutral amino acid transport systems of microvillous membrane of human placenta

1 reference

12 December 2020

Purification and Na+ uptake by human placental microvillus membrane vesicles prepared by three different methods

1 reference

12 December 2020

Protein turnover in the human fetus studied at term using stable isotope tracer amino acids.

1 reference

12 December 2020

Amino acid (system A) transporter activity in microvillous membrane vesicles from the placentas of appropriate and small for gestational age babies

1 reference

12 December 2020

10.1007/S10545-010-9141-3

Identifiers

DOI

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Dimensions Publication ID

31 July 2017

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31 July 2017

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