(Q34257527)

31 July 2017

title

Ablation of Sim1 neurons causes obesity through hyperphagia and reduced energy expenditure (English)

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31 July 2017

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Dong Xi

1

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31 July 2017

Nilay Gandhi

series ordinal

2

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31 July 2017

Meizan Lai

series ordinal

3

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31 July 2017

Bassil M Kublaoui

series ordinal

4

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31 July 2017

language of work or name

English

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publication date

27 April 2012

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31 July 2017

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31 July 2017

volume

7

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31 July 2017

issue

4

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31 July 2017

page(s)

e36453

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Creative Commons Attribution 4.0 International

31 July 2017

copyright license

start time

27 April 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3338647/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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Postnatal Sim1 deficiency causes hyperphagic obesity and reduced Mc4r and oxytocin expression

6 July 2018

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6 July 2018

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6 July 2018

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Inducible ablation of melanopsin-expressing retinal ganglion cells reveals their central role in non-image forming visual responses

6 July 2018

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Oxytocin deficiency mediates hyperphagic obesity of Sim1 haploinsufficient mice

6 July 2018

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Starvation after AgRP neuron ablation is independent of melanocortin signaling

6 July 2018

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Adenoviral-mediated modulation of Sim1 expression in the paraventricular nucleus affects food intake.

6 July 2018

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Sim1 haploinsufficiency impairs melanocortin-mediated anorexia and activation of paraventricular nucleus neurons

6 July 2018

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SIM1 overexpression partially rescues agouti yellow and diet-induced obesity by normalizing food intake.

6 July 2018

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A Cre-inducible diphtheria toxin receptor mediates cell lineage ablation after toxin administration.

6 July 2018

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Evidence for defective energy homeostasis in amyotrophic lateral sclerosis: benefit of a high-energy diet in a transgenic mouse model

6 July 2018

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Sim1 gene dosage modulates the homeostatic feeding response to increased dietary fat in mice

6 July 2018

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6 July 2018

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Neither agouti-related protein nor neuropeptide Y is critically required for the regulation of energy homeostasis in mice

6 July 2018

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Sim1 haploinsufficiency causes hyperphagia, obesity and reduction of the paraventricular nucleus of the hypothalamus

6 July 2018

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Neuronal circuitries involved in thermoregulation.

6 July 2018

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Paternal versus maternal transmission of a stimulatory G-protein alpha subunit knockout produces opposite effects on energy metabolism

6 July 2018

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Integration of NPY, AGRP, and melanocortin signals in the hypothalamic paraventricular nucleus: evidence of a cellular basis for the adipostat

6 July 2018

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alpha-Melanocyte-stimulating hormone is contained in nerve terminals innervating thyrotropin-releasing hormone-synthesizing neurons in the hypothalamic paraventricular nucleus and prevents fasting-induced suppression of prothyrotropin-releasing [...]

6 July 2018

1 reference

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Development of neuroendocrine lineages requires the bHLH-PAS transcription factor SIM1.

6 July 2018

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Posterodorsal amygdaloid lesions in rats: long-term effects on body weight

6 July 2018

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Arcuate nucleus neurons that project to the hypothalamic paraventricular nucleus: neuropeptidergic identity and consequences of adrenalectomy on mRNA levels in the rat.

6 July 2018

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Hypothalamic Integration: Organization of the Paraventricular and Supraoptic Nuclei

6 July 2018

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Immunohistochemical identification of neurons in the paraventricular nucleus of the hypothalamus that project to the medulla or to the spinal cord in the rat

6 July 2018

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6 July 2018

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PVN-hindbrain pathway involved in the hypothalamic hyperphagia-obesity syndrome

6 July 2018

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Neuropeptide Y suppresses sympathetic activity to interscapular brown adipose tissue in rats

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3338647

Direct hypothalamo-autonomic connections

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3338647

Anatomical substrates for the central control of sympathetic outflow to interscapular adipose tissue during cold exposure.

6 July 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0036453

Divergence of melanocortin pathways in the control of food intake and energy expenditure

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0036453

Hypothalamic paraventricular nucleus lesions produce overeating and obesity in the rat

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0036453

NPY/AgRP neurons are essential for feeding in adult mice but can be ablated in neonates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0036453

Running behavior and its energy cost in mice selectively bred for high voluntary locomotor activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0036453

Glutamate microinjected in the posterodorsal medial amygdala induces subtle increase in the consumption of a three-choice macronutrient self-selection diet in male rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0036453

Allocation of paraventricular and supraoptic neurons requires Sim1 function: a role for a Sim1 downstream gene PlexinC1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0036453

Thyrotropin-releasing hormone induced thermogenesis in Syrian hamsters: site of action and receptor subtype

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0036453

The neurochemical characterisation of hypothalamic pathways projecting polysynaptically to brown adipose tissue in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0036453

Oxytocin receptor-deficient mice developed late-onset obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0036453

Low sympathetic tone and obese phenotype in oxytocin-deficient mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0036453

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3338647

CNS origins of the sympathetic nervous system outflow to brown adipose tissue

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3338647

ARNT2 acts as the dimerization partner of SIM1 for the development of the hypothalamus

28 October 2018

1 reference

12 December 2020

Amygdala-lesion obesity: what is the role of the various amygdaloid nuclei?

1 reference

12 December 2020

Hypothalamic pathways underlying the endocrine, autonomic, and behavioral effects of leptin

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12 December 2020

Leptin activates neurons in ventrobasal hypothalamus and brainstem

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12 December 2020

Involvement of adrenergic receptor mechanisms within hypothalamus in the fever induced by amphetamine and thyrotropin-releasing hormone in the rat

1 reference

12 December 2020

Phaseolus vulgaris leuco-agglutinin tracing of intrahypothalamic connections of the lateral, ventromedial, dorsomedial and paraventricular hypothalamic nuclei in the rat

1 reference

12 December 2020

Lack of diet-induced thermogenesis following lesions of paraventricular nucleus in rats

1 reference

12 December 2020

Impaired thermoregulatory ability of oxytocin-deficient mice during cold-exposure

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0036453

Identifiers

DOI

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31 July 2017

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31 July 2017

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