(Q34257883)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25255025%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

title

Myeloid derived hypoxia inducible factor 1-alpha is required for protection against pulmonary Aspergillus fumigatus infection (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25255025%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

main subject

Aspergillus fumigatus

0 references

0 references

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25255025%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

Robert Cramer

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25255025%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

author name string

Kelly M Shepardson

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25255025%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

Anupam Jhingran

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25255025%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

Alayna Caffrey

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25255025%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

Benjamin T Suratt

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25255025%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

Brent L Berwin

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25255025%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

Tobias M Hohl

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25255025%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

publication date

25 September 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25255025%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25255025%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

volume

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25255025%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

issue

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25255025%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

page(s)

e1004378

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25255025%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 4.0 International

19 February 2020

copyright license

start time

25 September 2014

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4177996/fullTextXML

inferred from PubMed Central ID database lookup

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Factors regulated by interferon gamma and hypoxia-inducible factor 1A contribute to responses that protect mice from Coccidioides immitis infection

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Chemokine receptor Ccr1 drives neutrophil-mediated kidney immunopathology and mortality in invasive candidiasis

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Intrapulmonary administration of leukotriene B(4) augments neutrophil accumulation and responses in the lung to Klebsiella infection in CXCL1 knockout mice

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A new pharmacological agent (AKB-4924) stabilizes hypoxia inducible factor-1 (HIF-1) and increases skin innate defenses against bacterial infection

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The small GTPase RacA mediates intracellular reactive oxygen species production, polarized growth, and virulence in the human fungal pathogen Aspergillus fumigatus

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Essential role for neutrophils but not alveolar macrophages at early time points following Aspergillus fumigatus infection

6 July 2018

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A sterol-regulatory element binding protein is required for cell polarity, hypoxia adaptation, azole drug resistance, and virulence in Aspergillus fumigatus

6 July 2018

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NF-kappaB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1alpha

6 July 2018

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6 July 2018

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HIF-1alpha regulates epithelial inflammation by cell autonomous NFkappaB activation and paracrine stromal remodeling

6 July 2018

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Chlamydia pneumoniae directly interferes with HIF-1alpha stabilization in human host cells.

6 July 2018

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6 July 2018

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Early neutrophil recruitment and aggregation in the murine lung inhibit germination of Aspergillus fumigatus Conidia

6 July 2018

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Role of hypoxia-inducible factor (HIF)-1alpha versus HIF-2alpha in the regulation of HIF target genes in response to hypoxia, insulin-like growth factor-I, or loss of von Hippel-Lindau function: implications for targeting the HIF pathway

6 July 2018

1 reference

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6 July 2018

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Production of chemokine CXCL1/KC by okadaic acid through the nuclear factor-kappaB pathway

6 July 2018

1 reference

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Hypoxia-induced neutrophil survival is mediated by HIF-1alpha-dependent NF-kappaB activity

6 July 2018

1 reference

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Differences in patterns of infection and inflammation for corticosteroid treatment and chemotherapy in experimental invasive pulmonary aspergillosis

6 July 2018

1 reference

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Vascular endothelial growth factor and angiogenesis

6 July 2018

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Leukocyte adhesion during hypoxia is mediated by HIF-1-dependent induction of beta2 integrin gene expression

6 July 2018

1 reference

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The chemokine KC regulates HGF-stimulated epithelial cell morphogenesis

6 July 2018

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Killing of Aspergillus fumigatus by alveolar macrophages is mediated by reactive oxidant intermediates

6 July 2018

1 reference

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A novel role for the hypoxia inducible transcription factor HIF-1alpha: critical regulation of inflammatory cell function.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177996

Cloning of a gene encoding an Alt a 1 isoallergen differentially expressed by the necrotrophic fungus Alternaria brassicicola during Arabidopsis infection

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177996

HIF-1alpha is essential for myeloid cell-mediated inflammation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177996

Transient lung-specific expression of the chemokine KC improves outcome in invasive aspergillosis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177996

Negative regulation of nuclear factor-kappaB activation and function by glucocorticoids

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177996

A conserved family of prolyl-4-hydroxylases that modify HIF

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177996

Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177996

The CXC chemokine receptor 2, CXCR2, is the putative receptor for ELR+ CXC chemokine-induced angiogenic activity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177996

Neutrophil migration mechanisms, with an emphasis on the pulmonary vasculature.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177996

Growth regulated oncogene-alpha expression by murine squamous cell carcinoma promotes tumor growth, metastasis, leukocyte infiltration and angiogenesis by a host CXC receptor-2 dependent mechanism

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177996

CXC chemokine receptor-2 ligands are necessary components of neutrophil-mediated host defense in invasive pulmonary aspergillosis.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177996

Immunosuppression by glucocorticoids: inhibition of NF-kappa B activity through induction of I kappa B synthesis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177996

Two structurally distinct kappa B sequence motifs cooperatively control LPS-induced KC gene transcription in mouse macrophages.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177996

Energy metabolism of human neutrophils during phagocytosis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177996

Damage to Aspergillus fumigatus and Rhizopus oryzae hyphae by oxidative and nonoxidative microbicidal products of human neutrophils in vitro

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177996

The kinetics of 111indium distribution following injection of 111indium labelled autologous granulocytes in man.

6 July 2018

1 reference

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Control of cachectin (tumor necrosis factor) synthesis: mechanisms of endotoxin resistance.

6 July 2018

1 reference

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6 July 2018

1 reference

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Antibody-antigen interaction in the airway drives early granulocyte recruitment through BLT1.

21 January 2018

1 reference

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Murine CXCR1 is a functional receptor for GCP-2/CXCL6 and interleukin-8/CXCL8.

21 January 2018

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HIF-1alpha expression regulates the bactericidal capacity of phagocytes

21 January 2018

1 reference

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Pharmacologic augmentation of hypoxia-inducible factor-1alpha with mimosine boosts the bactericidal capacity of phagocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1004378

An intact canonical NF-κB pathway is required for inflammatory gene expression in response to hypoxia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1004378

Macrophage migration inhibitory factor counterregulates dexamethasone-mediated suppression of hypoxia-inducible factor-1 alpha function and differentially influences human CD4+ T cell proliferation under hypoxia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1004378

At the core of survival: Autophagy delays the onset of both apoptotic and necrotic cell death in a model of ischemic cell injury

21 January 2018

1 reference

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Role of TNF-alpha in pulmonary host defense in murine invasive aspergillosis.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177996

Changes in Apoptotic Gene Expression in Lymphocytes from Rheumatoid Arthritis and Systemic Lupus Erythematosus Patients Compared with Healthy Lymphocytes

28 October 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1004378

Differential effects of CD18, CD29, and CD49 integrin subunit inhibition on neutrophil migration in pulmonary inflammation

21 January 2018

1 reference

12 December 2020

The role of CD18-mediated adhesion in neutrophil sequestration induced by infusion of activated plasma in rabbits

1 reference

12 December 2020

Comparison of neutrophil and capillary diameters and their relation to neutrophil sequestration in the lung

1 reference

12 December 2020

Just how big is the pulmonary granulocyte pool?

1 reference

12 December 2020

Kinetic study of host defense and inflammatory response to Aspergillus fumigatus in steroid-induced immunosuppressed mice

1 reference

12 December 2020

Inhibition of murine neutrophil recruitment in vivo by CXC chemokine receptor antagonists

1 reference

12 December 2020

The pulmonary vascular sequestration of neutrophils in endotoxemia is initiated by an effect of endotoxin on the neutrophil in the rabbit

1 reference

12 December 2020

10.1371/JOURNAL.PPAT.1004378

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25255025%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25255025%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

PubMed publication ID

25255025

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25255025%20AND%20SRC:MED&resulttype=core&format=json