(Q34261701)

1 August 2017

title

Direct observation of multiple misfolding pathways in a single prion protein molecule (English)

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1 August 2017

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Hao Yu

1

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1 August 2017

Xia Liu

2

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1 August 2017

Krishna Neupane

3

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1 August 2017

Amar Nath Gupta

4

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1 August 2017

Angela M Brigley

5

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1 August 2017

Allison Solanki

6

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1 August 2017

Iveta Sosova

7

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1 August 2017

Michael T Woodside

8

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1 August 2017

language of work or name

English

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publication date

15 March 2012

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1 August 2017

number of pages

6

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Proceedings of the National Academy of Sciences of the United States of America

inferred from page(s)

published in

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1 August 2017

volume

109

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1 August 2017

issue

14

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1 August 2017

page(s)

5283-5288

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The complex folding network of single calmodulin molecules

1 August 2017

cites work

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Single-molecule force spectroscopy of the add adenine riboswitch relates folding to regulatory mechanism

28 July 2018

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Single-molecule fluorescence reveals sequence-specific misfolding in multidomain proteins

28 July 2018

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Optical trapping with high forces reveals unexpected behaviors of prion fibrils

28 July 2018

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Cellular strategies for controlling protein aggregation

28 July 2018

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The folding cooperativity of a protein is controlled by its chain topology

28 July 2018

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Early aggregation steps in alpha-synuclein as measured by FCS and FRET: evidence for a contagious conformational change.

28 July 2018

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Full distance-resolved folding energy landscape of one single protein molecule

28 July 2018

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The consequences of pathogenic mutations to the human prion protein

28 July 2018

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Converging concepts of protein folding in vitro and in vivo

28 July 2018

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Folding kinetics of the human prion protein probed by temperature jump.

28 July 2018

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Prion diseases and their biochemical mechanisms

28 July 2018

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Getting a grip on prions: oligomers, amyloids, and pathological membrane interactions

28 July 2018

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alpha-Synuclein misfolding: single molecule AFM force spectroscopy study

28 July 2018

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Direct characterization of amyloidogenic oligomers by single-molecule fluorescence

28 July 2018

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Nanomechanical properties of human prion protein amyloid as probed by force spectroscopy

28 July 2018

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28 July 2018

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Protein-DNA chimeras for single molecule mechanical folding studies with the optical tweezers

28 July 2018

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Direct observation of hierarchical folding in single riboswitch aptamers

28 July 2018

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Molecular architecture of human prion protein amyloid: a parallel, in-register beta-structure

28 July 2018

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Structural and hydration properties of the partially unfolded states of the prion protein

28 July 2018

1 reference

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A natively unfolded yeast prion monomer adopts an ensemble of collapsed and rapidly fluctuating structures.

28 July 2018

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Direct measurement of the full, sequence-dependent folding landscape of a nucleic acid

28 July 2018

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28 July 2018

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Protein misfolding, functional amyloid, and human disease

28 July 2018

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Direct observation of the three-state folding of a single protein molecule

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325692

The most infectious prion protein particles.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325692

Prion protein NMR structures of cats, dogs, pigs, and sheep

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325692

Mechanical processes in biochemistry

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325692

Evidence for assembly of prions with left-handed beta-helices into trimers

28 July 2018

1 reference

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From conversion to aggregation: protofibril formation of the prion protein

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325692

The pleated sheet, a new layer configuration of polypeptide chains

28 July 2018

1 reference

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NMR-detected hydrogen exchange and molecular dynamics simulations provide structural insight into fibril formation of prion protein fragment 106-126.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325692

The role of disulfide bridge in the folding and stability of the recombinant human prion protein

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325692

Solution structure of a 142-residue recombinant prion protein corresponding to the infectious fragment of the scrapie isoform

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325692

Stretching DNA with optical tweezers

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325692

Structural clues to prion replication

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325692

Conversion of alpha-helices into beta-sheets features in the formation of the scrapie prion proteins

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325692

Direct observation of chaperone-induced changes in a protein folding pathway

28 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1107736109

NMR solution structure of the human prion protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1107736109

Early intermediate in human prion protein folding as evidenced by ultrarapid mixing experiments.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1107736109

The elusive intermediate on the folding pathway of the prion protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1107736109

Locally disordered conformer of the hamster prion protein: a crucial intermediate to PrPSc?

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1107736109

Passive all-optical force clamp for high-resolution laser trapping.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1107736109

Definable equilibrium states in the folding of human prion protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1107736109

Neurotoxicity and neurodegeneration when PrP accumulates in the cytosol

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1107736109

Detailed biophysical characterization of the acid-induced PrP(c) to PrP(β) conversion process.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1107736109

Prion protein selectively binds copper(II) ions

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1107736109

The oligomerization properties of prion protein are restricted to the H2H3 domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1107736109

Detection and Analysis of Protein Aggregation with Confocal Single Molecule Fluorescence Spectroscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1107736109

Structural mobility of the human prion protein probed by backbone hydrogen exchange

21 January 2018

1 reference

12 December 2020

Oligomerization of the human prion protein proceeds via a molten globule intermediate

1 reference

12 December 2020

Extremely rapid folding of the C-terminal domain of the prion protein without kinetic intermediates

1 reference

12 December 2020

Human prion proteins expressed in Escherichia coli and purified by high-affinity column refolding

1 reference

12 December 2020

Single protein misfolding events captured by atomic force microscopy

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.1107736109

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1 August 2017

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1 August 2017

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