(Q34262167)

English

Contribution of interleukin-12 (IL-12) and the CD28/B7 and CD40/CD40 ligand pathways to the development of a pathological T-cell response in IL-10-deficient mice.

scientific article

In more languages

default for all languages

No label defined

No description defined

Statements

scholarly article

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12438373%20AND%20SRC:MED&resulttype=core&format=json

15 December 2019

Contribution of interleukin-12 (IL-12) and the CD28/B7 and CD40/CD40 ligand pathways to the development of a pathological T-cell response in IL-10-deficient mice (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12438373%20AND%20SRC:MED&resulttype=core&format=json

15 December 2019

3

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12438373%20AND%20SRC:MED&resulttype=core&format=json

15 December 2019

author name string

Ulrike Wille

1

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12438373%20AND%20SRC:MED&resulttype=core&format=json

15 December 2019

Eric N Villegas

2

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12438373%20AND%20SRC:MED&resulttype=core&format=json

15 December 2019

Robert Peach

4

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12438373%20AND%20SRC:MED&resulttype=core&format=json

15 December 2019

Christopher A Hunter

5

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12438373%20AND%20SRC:MED&resulttype=core&format=json

15 December 2019

language of work or name

0 references

publication date

1 December 2002

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12438373%20AND%20SRC:MED&resulttype=core&format=json

15 December 2019

Infection and Immunity

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12438373%20AND%20SRC:MED&resulttype=core&format=json

15 December 2019

70

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12438373%20AND%20SRC:MED&resulttype=core&format=json

15 December 2019

12

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12438373%20AND%20SRC:MED&resulttype=core&format=json

15 December 2019

6940-6947

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12438373%20AND%20SRC:MED&resulttype=core&format=json

15 December 2019

Interleukin-10 and the interleukin-10 receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133089

6 July 2018

Efficacy and safety of recombinant human activated protein C for severe sepsis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133089

6 July 2018

Interleukin-18 (IL-18) enhances innate IL-12-mediated resistance to Toxoplasma gondii

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133089

6 July 2018

Human dendritic cells discriminate between viable and killed Toxoplasma gondii tachyzoites: dendritic cell activation after infection with viable parasites results in CD28 and CD40 ligand signaling that controls IL-12-dependent and -independent T ce

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133089

6 July 2018

Lessons from genetically engineered animal models. XII. IL-10-deficient (IL-10(-/-) mice and intestinal inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133089

6 July 2018

Blockade of costimulation prevents infection-induced immunopathology in interleukin-10-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133089

6 July 2018

Chronic colitis in IL-10-/- mice: insufficient counter regulation of a Th1 response.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133089

6 July 2018

The CD40/CD40 ligand interaction is required for resistance to toxoplasmic encephalitis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133089

6 July 2018

CD40-CD40 ligand interaction is central to cell-mediated immunity against Toxoplasma gondii: patients with hyper IgM syndrome have a defective type 1 immune response that can be restored by soluble CD40 ligand trimer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133089

6 July 2018

CD40 signaling of monocyte inflammatory cytokine synthesis through an ERK1/2-dependent pathway. A target of interleukin (il)-4 and il-10 anti-inflammatory action

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133089

6 July 2018

Role of interleukin-10 in regulation of T-cell-dependent and T-cell-independent mechanisms of resistance to Toxoplasma gondii

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133089

6 July 2018

Studies with IL-10-/- mice: an overview.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133089

6 July 2018

Enterocolitis and colon cancer in interleukin-10-deficient mice are associated with aberrant cytokine production and CD4(+) TH1-like responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133089

6 July 2018

Ligation of CD40 on dendritic cells triggers production of high levels of interleukin-12 and enhances T cell stimulatory capacity: T-T help via APC activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133089

6 July 2018

High level IL-12 production by murine dendritic cells: upregulation via MHC class II and CD40 molecules and downregulation by IL-4 and IL-10.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133089

6 July 2018

T helper cell 1-type CD4+ T cells, but not B cells, mediate colitis in interleukin 10-deficient mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133089

6 July 2018

CD40/CD40 ligand interactions are required for T cell-dependent production of interleukin-12 by mouse macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133089

6 July 2018

Cytokine mRNA in the central nervous system of SCID mice infected with Toxoplasma gondii: importance of T-cell-independent regulation of resistance to T. gondii.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133089

6 July 2018

Interleukin-10-deficient mice develop chronic enterocolitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133089

6 July 2018

Interleukin 10 (IL-10) inhibits human lymphocyte interferon gamma-production by suppressing natural killer cell stimulatory factor/IL-12 synthesis in accessory cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133089

6 July 2018

Interleukin 12 and tumor necrosis factor alpha are costimulators of interferon gamma production by natural killer cells in severe combined immunodeficiency mice with listeriosis, and interleukin 10 is a physiologic antagonist

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133089

6 July 2018

Interleukin-12 enhances murine survival against acute toxoplasmosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133089

6 July 2018

Cloning of B7-2: a CTLA-4 Counter-Receptor That Costimulates Human T Cell Proliferation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133089

6 July 2018

B70 antigen is a second ligand for CTLA-4 and CD28

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133089

6 July 2018

B7-1 and B7-2 do not deliver identical costimulatory signals, since B7-2 but not B7-1 preferentially costimulates the initial production of IL-4.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133089

6 July 2018

CD80 (B7) and CD86 (B70) provide similar costimulatory signals for T cell proliferation, cytokine production, and generation of CTL

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133089

6 July 2018

Activation of human dendritic cells through CD40 cross-linking.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133089

6 July 2018

Interleukin-10 inhibits B7 and intercellular adhesion molecule-1 expression on human monocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133089

6 July 2018

Interferon-gamma: the major mediator of resistance against Toxoplasma gondii

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133089

6 July 2018

Two types of mouse T helper cell. IV. Th2 clones secrete a factor that inhibits cytokine production by Th1 clones

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133089

6 July 2018

Importance of endogenous IFN-gamma for prevention of toxoplasmic encephalitis in mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133089

6 July 2018

Treatment of toxoplasmic encephalitis in mice with recombinant gamma interferon

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133089

6 July 2018

Interleukin 10(IL-10) inhibits cytokine synthesis by human monocytes: an autoregulatory role of IL-10 produced by monocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133089

6 July 2018

IL-10 inhibits cytokine production by activated macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133089

6 July 2018

CTLA-4 is a second receptor for the B cell activation antigen B7

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133089

6 July 2018

Interleukin 10 (IL-10) and viral IL-10 strongly reduce antigen-specific human T cell proliferation by diminishing the antigen-presenting capacity of monocytes via downregulation of class II major histocompatibility complex expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133089

6 July 2018

Differential CD86/B7-2 expression and cytokine secretion induced by Toxoplasma gondii in macrophages from resistant or susceptible BALB H-2 congenic mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133089

28 October 2018

Interleukin-10 down-regulates MHC class II alphabeta peptide complexes at the plasma membrane of monocytes by affecting arrival and recycling.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133089

28 October 2018

Requirement for CD40 ligand in costimulation induction, T cell activation, and experimental allergic encephalomyelitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133089

28 October 2018

CD40 ligand-dependent T cell activation: requirement of B7-CD28 signaling through CD40.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133089

28 October 2018

In the absence of endogenous IL-10, mice acutely infected with Toxoplasma gondii succumb to a lethal immune response dependent on CD4+ T cells and accompanied by overproduction of IL-12, IFN-gamma and TNF-alpha

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133089

28 October 2018

Interleukin-12 primes human CD4 and CD8 T cell clones for high production of both interferon-gamma and interleukin-10.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133089

28 October 2018

Tumor rejection requires a CTLA4 ligand provided by the host or expressed on the tumor: superiority of B7-1 over B7-2 for active tumor immunization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133089

28 October 2018

Parasite-induced IL-12 stimulates early IFN-gamma synthesis and resistance during acute infection with Toxoplasma gondii.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133089

28 October 2018

IL-10 inhibits macrophage costimulatory activity by selectively inhibiting the up-regulation of B7 expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133089

28 October 2018

Interleukin-10 does not contribute to the pathogenesis of a virulent strain of Toxoplasma gondii

1 reference

https://pubmed.ncbi.nlm.nih.gov/12438373

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Simple technique for the direct isolation of toxoplasma tissue cysts from fetal ovine brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/12438373

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Western Blot analysis of the antigens of Toxoplasma gondii recognized by human IgM and IgG antibodies

1 reference

https://pubmed.ncbi.nlm.nih.gov/12438373

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of murine interferon gamma on murine toxoplasmosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12438373

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Different regulation of the L3T4-T cell subset by B cells in different mouse strains bearing the H-2k haplotype

1 reference

https://pubmed.ncbi.nlm.nih.gov/12438373

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vivo and in vitro activation of alveolar macrophages by recombinant interferon-gamma

1 reference

https://pubmed.ncbi.nlm.nih.gov/12438373

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Microbiostatic effect of murine-activated macrophages for Toxoplasma gondii. Role for synthesis of inorganic nitrogen oxides from L-arginine

1 reference

https://pubmed.ncbi.nlm.nih.gov/12438373

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activated T cells induce interleukin-12 production by monocytes via CD40-CD40 ligand interaction

1 reference

https://pubmed.ncbi.nlm.nih.gov/12438373

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin‐10 differentially regulates B7‐1 (CD80) and B7‐2 (CD86) expression on human peripheral blood dendritic cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12438373

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

B7-1 is superior to B7-2 costimulation in the induction and maintenance of T cell-mediated antileukemia immunity. Further evidence that B7-1 and B7-2 are functionally distinct

1 reference

https://pubmed.ncbi.nlm.nih.gov/12438373

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-12-induced IL-10 production by human T cells as a negative feedback for IL-12-induced immune responses

1 reference

https://pubmed.ncbi.nlm.nih.gov/12438373

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Costimulation of IL-4 production by murine B7-1 and B7-2 molecules

1 reference

https://pubmed.ncbi.nlm.nih.gov/12438373

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human B7-1 is more efficient than B7-2 in providing co-stimulation for alloantigen-specific T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12438373

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-4 and IL-10 modulation of CD40-mediated signaling of monocyte IL-1beta synthesis and rescue from apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12438373

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD40 ligand/CD40 stimulation regulates the production of IFN-gamma from human peripheral blood mononuclear cells in an IL-12- and/or CD28-dependent manner

1 reference

https://pubmed.ncbi.nlm.nih.gov/12438373

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of CD80 (B7.1) and CD86 (B7.2) in the immune response to an intracellular pathogen.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12438373

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibitory and stimulatory effects of IL-10 on human CD8+ T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12438373

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The crucial role of IL-10 in the suppression of the immunological response in mice exposed to staphylococcal enterotoxin B

1 reference

https://pubmed.ncbi.nlm.nih.gov/12438373

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-12, but not IFN-gamma, plays a major role in sustaining the chronic phase of colitis in IL-10-deficient mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/12438373

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

B7.1 is a quantitatively stronger costimulus than B7.2 in the activation of naive CD8+ TCR-transgenic T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12438373

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reciprocal control of T helper cell and dendritic cell differentiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/12438373

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/IAI.70.12.6940-6947.2002

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12438373%20AND%20SRC:MED&resulttype=core&format=json

15 December 2019

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12438373%20AND%20SRC:MED&resulttype=core&format=json

15 December 2019

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12438373%20AND%20SRC:MED&resulttype=core&format=json

15 December 2019

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q34262167&oldid=2047654198"