(Q34263373)

English

Inactivation of beef brain alpha-ketoglutarate dehydrogenase complex by valproic acid and valproic acid metabolites. Possible mechanism of anticonvulsant and toxic actions

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scholarly article

1 reference

Europe PubMed Central

1 August 2017

Inactivation of beef brain alpha-ketoglutarate dehydrogenase complex by valproic acid and valproic acid metabolites. Possible mechanism of anticonvulsant and toxic actions (English)

1 reference

Europe PubMed Central

1 August 2017

author name string

A S Luder

1

1 reference

Europe PubMed Central

1 August 2017

J K Parks

2

1 reference

Europe PubMed Central

1 August 2017

F Frerman

3

1 reference

Europe PubMed Central

1 August 2017

W D Parker

4

1 reference

Europe PubMed Central

1 August 2017

language of work or name

0 references

publication date

1 November 1990

1 reference

Europe PubMed Central

1 August 2017

Journal of Clinical Investigation

1 reference

Europe PubMed Central

1 August 2017

86

1 reference

Europe PubMed Central

1 August 2017

5

1 reference

Europe PubMed Central

1 August 2017

1574-1581

1 reference

Europe PubMed Central

1 August 2017

Protein measurement with the Folin phenol reagent

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=296905

28 July 2018

Pharmacodynamic properties of N-dipropylacetic acid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=296905

28 July 2018

Valproate-induced hepatic injury: analyses of 23 fatal cases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=296905

28 July 2018

Comparative evaluation of anticonvulsant and toxic potencies of valproic acid and 2-en-valproic acid in different animal models of epilepsy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=296905

28 July 2018

Distribution of valproic acid and its metabolites in various brain areas of dogs and rats after acute and prolonged treatment.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=296905

28 July 2018

Mechanism of anticonvulsant action of valproate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=296905

28 July 2018

The reliability of molecular weight determinations by dodecyl sulfate-polyacrylamide gel electrophoresis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=296905

28 July 2018

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=296905

28 July 2018

Alpha-Keto acid dehydrogenase complexes, V. Macromolecular organization of pyruvate and alpha-ketoglutarate dehydrogenase complexes isolated from beef kidney mitochondria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=296905

28 July 2018

Regulation of mitochondrial alpha-ketoglutarate metabolism by product inhibition at alpha-ketoglutarate dehydrogenase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=296905

28 July 2018

Effect of sodium n-dipropylacetate on audiogenic seizures and brain -aminobutyric acid level.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=296905

28 July 2018

Brain alpha-ketoglutarate dehydrogenase complex: kinetic properties, regional distribution, and effects of inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=296905

28 July 2018

A study of the metabolism of [U-14C]3-methyl-2-oxopentanoate by rat liver mitochondria using h.p.l.c. with continuous on-line monitoring of radioactive intact acyl-coenzyme A intermediates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=296905

28 July 2018

Valproate causes metabolic disturbance in normal man.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=296905

28 July 2018

Valproic acid: reversibly acting drug?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=296905

28 July 2018

Preparation of synaptic and nonsynaptic mitochondria from mammalian brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=296905

28 July 2018

A Controlled Study of the Effect of Sodium Valproate on Photosensitive Epilepsy and Its Prognosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=296905

28 July 2018

Effects of sodium dipropylacetate on .GAMMA.-aminobutyric acid and biogenic amines in rat brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=296905

28 July 2018

Partial purification and properties of branched-chain 2-oxo acid dehydrogenase of ox liver

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=296905

28 July 2018

Studies on the mechanism and kinetics of the 2-oxoglutarate dehydrogenase system from pig heart

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=296905

28 July 2018

The composition of the ketoglutarate dehydrogenase complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=296905

28 October 2018

Statistical estimations in enzyme kinetics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=296905

28 October 2018

The subunit molecular weights of the alpha-ketoacid dehydrogenase multienzyme complexes from E. coli.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=296905

28 October 2018

Inactivation of the 2-ketoglutarate and pyruvate dehydrogenase complexes of beef heart by branched chain keto acids.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=296905

28 October 2018

-Keto acid dehydrogenase complexes. XVI. Studies on the subunit structure of the pyruvate dehydrogenase complexes from bovine kidney and heart

1 reference

https://pubmed.ncbi.nlm.nih.gov/2243131

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of branched chain alpha-ketoacids on the metabolism of isolated rat liver cells. III. Interactions with pyruvate dehydrogenase

1 reference

https://pubmed.ncbi.nlm.nih.gov/2243131

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of branched chain alpha-ketoacids on the metabolism of isolated rat liver cells. II. Interactions with gluconeogenesis and urea synthesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/2243131

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxidative metabolism of 4-aminobutyrate by rat brain mitochondria: inhibition by branched-chain fatty acid

1 reference

https://pubmed.ncbi.nlm.nih.gov/2243131

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An analysis of partial reactions in the overall chain elongation of saturated and unsaturated fatty acids by rat liver microsomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/2243131

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effects of valproate on intermediary metabolism in isolated rat hepatocytes and intact rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/2243131

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Influence of valproic acid on hepatic carbohydrate and lipid metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/2243131

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interactions between alpha-ketoisovalerate metabolism and the pathways of gluconeogenesis and urea synthesis in isolated hepatocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/2243131

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mammalian alpha-keto acid dehydrogenase complexes. IV. Substrate specificities and kinetic properties of the pig heart pyruvate and 2-oxyoglutarate dehydrogenase complexes

1 reference

https://pubmed.ncbi.nlm.nih.gov/2243131

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Studies on distribution and metabolism of valproate in rat brain, liver, and kidney

1 reference

https://pubmed.ncbi.nlm.nih.gov/2243131

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mammalian alpha-keto acid dehydrogenase complexes. 8. Properties and subunit composition of the pig heart lipoate succinyltransferase

1 reference

https://pubmed.ncbi.nlm.nih.gov/2243131

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mammalian alpha-keto acid dehydrogenase complexes. II. An improved procedure for the preparation of 2-oxoglutarate dehydrogenase complex from pig heart muscle

1 reference

https://pubmed.ncbi.nlm.nih.gov/2243131

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of branched chain alpha-ketoacids on the metabolism of isolated rat liver cells. I. Regulation of branched chain alpha-ketoacid metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/2243131

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure, assembly and function of mammalian alpha-keto acid dehydrogenase complexes

1 reference

https://pubmed.ncbi.nlm.nih.gov/2243131

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibitory effects of sodium valproate on oxidative phosphorylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/2243131

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Valproic acid: brain and plasma levels of the drug and its metabolites, anticonvulsant effects and gamma-aminobutyric acid (GABA) metabolism in the mouse

1 reference

https://pubmed.ncbi.nlm.nih.gov/2243131

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The enzymatic synthesis of some potential photoaffinity analogs of benzoyl-coenzyme A

1 reference

https://pubmed.ncbi.nlm.nih.gov/2243131

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1172/JCI114877

1 reference

Europe PubMed Central

1 August 2017

1 reference

Europe PubMed Central

1 August 2017

1 reference

Europe PubMed Central

1 August 2017

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