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NF-kappaB signaling and human disease
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instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
11377967
retrieved
1 August 2017
review article
1 reference
stated in
Europe PubMed Central
title
NF-kappaB signaling and human disease
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
11377967
retrieved
1 August 2017
main subject
NF-κB
1 reference
based on heuristic
inferred from title
author name string
Aradhya S
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
11377967
retrieved
1 August 2017
Nelson DL
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed ID
11377967
retrieved
1 August 2017
publication date
1 June 2001
1 reference
stated in
Europe PubMed Central
PubMed ID
11377967
retrieved
1 August 2017
published in
Current Opinion in Genetics & Development
1 reference
stated in
Europe PubMed Central
PubMed ID
11377967
retrieved
1 August 2017
volume
11
1 reference
stated in
Europe PubMed Central
PubMed ID
11377967
retrieved
1 August 2017
issue
3
1 reference
stated in
Europe PubMed Central
PubMed ID
11377967
retrieved
1 August 2017
page(s)
300-306
1 reference
stated in
Europe PubMed Central
PubMed ID
11377967
retrieved
1 August 2017
cites work
Inducibility of kappa immunoglobulin enhancer-binding protein Nf-kappa B by a posttranslational mechanism
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900194-5
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7 January 2021
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inferred from DOI database lookup
Function and activation of NF-kappa B in the immune system
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reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900194-5
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7 January 2021
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NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900194-5
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7 January 2021
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Nuclear factor-kappaB: a pivotal transcription factor in chronic inflammatory diseases
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900194-5
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7 January 2021
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An essential role for NF-kappaB in preventing TNF-alpha-induced cell death
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900194-5
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7 January 2021
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NF-kappaB to the rescue: RELs, apoptosis and cellular transformation
1 reference
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reference URL
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7 January 2021
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The IKK complex: an integrator of all signals that activate NF-kappaB?
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https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900194-5
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7 January 2021
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Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity
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7 January 2021
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NF-kappa B activation by the pre-T cell receptor serves as a selective survival signal in T lymphocyte development
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900194-5
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7 January 2021
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Requirement for NF-kappaB in osteoclast and B-cell development
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Crossref
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https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900194-5
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7 January 2021
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Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-kappa B
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900194-5
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7 January 2021
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It's got you covered. NF-kappaB in the epidermis.
1 reference
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https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900194-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of NF-kappaB activity results in disruption of the apical ectodermal ridge and aberrant limb morphogenesis.
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900194-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
X-linked anhidrotic (hypohidrotic) ectodermal dysplasia is caused by mutation in a novel transmembrane protein
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900194-5
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7 January 2021
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The Tabby phenotype is caused by mutation in a mouse homologue of the EDA gene that reveals novel mouse and human exons and encodes a protein (ectodysplasin-A) with collagenous domains
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900194-5
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7 January 2021
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Two-amino acid molecular switch in an epithelial morphogen that regulates binding to two distinct receptors
1 reference
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https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900194-5
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7 January 2021
based on heuristic
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Mutations in the human homologue of mouse dl cause autosomal recessive and dominant hypohidrotic ectodermal dysplasia
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900194-5
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7 January 2021
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Involvement of a novel Tnf receptor homologue in hair follicle induction.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900194-5
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7 January 2021
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The ectodermal dysplasia receptor activates the nuclear factor-kappaB, JNK, and cell death pathways and binds to ectodysplasin A
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900194-5
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7 January 2021
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Mutations in TNFRSF11A, affecting the signal peptide of RANK, cause familial expansile osteolysis
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900194-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
RANK is the essential signaling receptor for osteoclast differentiation factor in osteoclastogenesis
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900194-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
Tumor necrosis factor receptor family member RANK mediates osteoclast differentiation and activation induced by osteoprotegerin ligand
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900194-5
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7 January 2021
based on heuristic
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Genomic rearrangement in NEMO impairs NF-kappaB activation and is a cause of incontinentia pigmenti. The International Incontinentia Pigmenti (IP) Consortium
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900194-5
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7 January 2021
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RANK is the intrinsic hematopoietic cell surface receptor that controls osteoclastogenesis and regulation of bone mass and calcium metabolism
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900194-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
Required and nonessential functions of nuclear factor-kappa B in bone cells
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900194-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
VEGFs, receptors and angiogenesis
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900194-5
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7 January 2021
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Missense mutations interfere with VEGFR-3 signalling in primary lymphoedema
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900194-5
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7 January 2021
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Cardiovascular failure in mouse embryos deficient in VEGF receptor-3
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Crossref
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https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900194-5
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7 January 2021
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Molecular basis of human piebaldism
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900194-5
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7 January 2021
based on heuristic
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Incontinentia pigmenti (Bloch-Sulzberger syndrome).
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900194-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
Selection against mutant alleles in blood leukocytes is a consistent feature in Incontinentia Pigmenti type 2.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900194-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
X-inactivation and marker studies in three families with incontinentia pigmenti: implications for counselling and gene localisation
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900194-5
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7 January 2021
based on heuristic
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Retinal and other manifestations of incontinentia pigmenti (Bloch-Sulzberger syndrome).
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900194-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
The blinding mechanisms of incontinentia pigmenti
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900194-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
Optic nerve neovascularization in incontinentia pigmenti
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900194-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
Incontinentia pigmenti: clinical and neuroradiologic features.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900194-5
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7 January 2021
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Complementation cloning of NEMO, a component of the IkappaB kinase complex essential for NF-kappaB activation
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900194-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
IKK-gamma is an essential regulatory subunit of the IkappaB kinase complex
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900194-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
NEMO/IKK gamma-deficient mice model incontinentia pigmenti.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900194-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Female mice heterozygous for IKK gamma/NEMO deficiencies develop a dermatopathy similar to the human X-linked disorder incontinentia pigmenti
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900194-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
Atypical forms of incontinentia pigmenti in male individuals result from mutations of a cytosine tract in exon 10 of NEMO (IKK-gamma)
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900194-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A novel X-linked disorder of immune deficiency and hypohidrotic ectodermal dysplasia is allelic to incontinentia pigmenti and due to mutations in IKK-gamma (NEMO)
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900194-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
X-linked anhidrotic ectodermal dysplasia with immunodeficiency is caused by impaired NF-kappaB signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900194-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Specific missense mutations in NEMO result in hyper-IgM syndrome with hypohydrotic ectodermal dysplasia
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900194-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
NF-kappa B: ten years after
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900194-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
Severe liver degeneration in mice lacking the IkappaB kinase 2 gene
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900194-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The IKKbeta subunit of IkappaB kinase (IKK) is essential for nuclear factor kappaB activation and prevention of apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900194-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
IKK1-deficient mice exhibit abnormal development of skin and skeleton
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900194-5
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7 January 2021
based on heuristic
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Abnormal morphogenesis but intact IKK activation in mice lacking the IKKalpha subunit of IkappaB kinase
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900194-5
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7 January 2021
based on heuristic
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Limb and skin abnormalities in mice lacking IKKalpha
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900194-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
NF-kappaB determines localization and features of cell death in epidermis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900194-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Alterations in NF-kappaB function in transgenic epithelial tissue demonstrate a growth inhibitory role for NF-kappaB.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900194-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
Suppression of retinal neovascularization in vivo by inhibition of vascular endothelial growth factor (VEGF) using soluble VEGF-receptor chimeric proteins
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900194-5
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7 January 2021
based on heuristic
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B cell lymphoma-associated chromosomal translocation involves candidate oncogene lyt-10, homologous to NF-kappa B p50
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900194-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
Local administration of antisense phosphorothioate oligonucleotides to the p65 subunit of NF-kappa B abrogates established experimental colitis in mice
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900194-5
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7 January 2021
based on heuristic
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Diverse roles of the tumor necrosis factor family member TRANCE in skeletal physiology revealed by TRANCE deficiency and partial rescue by a lymphocyte-expressed TRANCE transgene
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900194-5
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7 January 2021
based on heuristic
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Interleukin (IL)-1 receptor-associated kinase (IRAK) requirement for optimal induction of multiple IL-1 signaling pathways and IL-6 production
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2800%2900194-5
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7 January 2021
based on heuristic
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Identifiers
DOI
10.1016/S0959-437X(00)00194-5
1 reference
stated in
Europe PubMed Central
PubMed ID
11377967
retrieved
1 August 2017
PubMed ID
11377967
1 reference
stated in
Europe PubMed Central
PubMed ID
11377967
retrieved
1 August 2017
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