(Q34268419)

1 August 2017

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title

Molecular mechanisms of general anaesthesia. (English)

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1 August 2017

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Franks NP

1

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1 August 2017

Lieb WR

series ordinal

2

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1 August 2017

language of work or name

English

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publication date

1 December 1982

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1 August 2017

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1 August 2017

volume

300

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1 August 2017

issue

5892

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1 August 2017

page(s)

487-493

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https://scigraph.springernature.com/pub.10.1038/300487a0

1 August 2017

exact match

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cites work

Some effects of aliphatic hydrocarbons on the electrical capacity and ionic currents of the squid giant axon membrane

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Zur Theorie der Alkoholnarkose

21 January 2018

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7 January 2021

Zur Theorie der Alkoholnarkose

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7 January 2021

Where do general anaesthetics act?

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7 January 2021

Solubility coefficients for inhaled anaesthetics for water, oil and biological media

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7 January 2021

Some Physical Mechanisms in Narcosis

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7 January 2021

TEMPERATURE DEPENDENCE OF ANESTHESIA IN GOLDFISH.

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7 January 2021

Partition coefficients and the structure-activity relation of the anesthetic gases

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7 January 2021

Physical parameters of the anesthetic site

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7 January 2021

Physicochemical approaches to the mode of action of general anesthetics.

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7 January 2021

Pressure reversal of anaesthesia.

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7 January 2021

Pressure reversal of narcosis produced by anaesthetics, narcotics and tranquillisers

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7 January 2021

Pressure reversal of general anaesthesia--a multi-site expansion hypothesis

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7 January 2021

Pressure, temperature, and repetitive impulse generation in crustacean axons

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7 January 2021

Anesthetics inhibit pressure-induced repetitive impulse generation

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7 January 2021

Variation with temperature of the solubilities of inhaled anaesthetics in water, oil and biological media.

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7 January 2021

Effect of hypothermia in dogs on anesthetizing and apneic doses of inhalation agents. Determination of the anesthetic index (Apnea/MAC).

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7 January 2021

Temperature dependence of halothane and cyclopropane anesthesia in dogs: correlation with some theories of anesthetic action

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7 January 2021

Hyperthermia and halothane MAC in the dog.

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7 January 2021

Correlation of general anesthetic potency with solubility in membranes

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7 January 2021

Interpretation of nonelectrolyte partition coefficients between dimyristoyl lecithin and water.

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7 January 2021

The structure of lipid bilayers and the effects of general anaesthetics. An x-ray and neutron diffraction study.

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7 January 2021

Effect of a local anaesthetic on hydrocarbon chain order in membranes

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7 January 2021

Do clinical levels of general anaesthetics affect lipid bilayers? Evidence from Raman scattering.

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7 January 2021

Halothane Increases Membrane Fluidity and Stimulates Sphingomyelin Degradation by Membrane-Bound Neutral Sphingomyelinase of Synaptosomal Plasma Membranes from Calf Brain Already at Clinical Concentrations

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7 January 2021

General anaesthetics can selectively perturb lipid bilayer membranes

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7 January 2021

Degenerate perturbations of protein structure as the mechanism of anaesthetic action

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7 January 2021

The effect of anaesthetic-like molecules on the phase transition in smectic mesophases of dipalmitoyllecithin. I. The normal alcohol up to C equals 9 and three inhalation anaesthetics.

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7 January 2021

Effect of anesthetics and pressure on the thermotropic behavior of multilamellar dipalmitoylphosphatidylcholine liposomes

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7 January 2021

Antagonism between high pressure and anesthetics in the thermal phase-transition of dipalmitoyl phosphatidylcholine bilayer.

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7 January 2021

Interactions between anesthetics and lipid mixtures. Normal alcohols

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7 January 2021

Differential effects on phospholipid phase transitions produced by structurally related long-chain alcohols

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7 January 2021

A Unitary Theory of Anesthesia Based on Lateral Phase Separations in Nerve Membranes

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7 January 2021

Relation between the ability of various compounds to block nervous conduction and their penetration into a monomolecular layer of nerve-tissue lipoids

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7 January 2021

The affinity of narcotic agents for interfacial films

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7 January 2021

Cation Permeability of Phospholipid Model Membranes: Effect of Narcotics

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7 January 2021

Anesthetic interaction with a model cell membrane: expansion, phase transition, and melting of the lecithin monolayer.

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7 January 2021

General anesthetics expand cell membranes at surgical concentrations

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7 January 2021

The molecular mechanisms of anaesthesia

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7 January 2021

The organization of n-alkanes in lipid bilayers

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7 January 2021

Local anaesthetic benzyl alcohol increases membrane thickness

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7 January 2021

Effect of benzyl alcohol on lipid bilayers. A comparisons of bilayer systems

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7 January 2021

Effect of the anesthetics benzyl alcohol and chloroform on bilayers made from monolayers

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7 January 2021

A dynamic X-ray diffraction study of anaesthesia action. Changes in myelin structure and electrical activity recorded simultaneously from frog sciatic nerves treated with n-alkanes.

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7 January 2021

The membrane expansion theory of anesthesia: direct evidence using ethanol and a high-precision density meter.

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7 January 2021

Is membrane expansion relevant to anaesthesia?

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7 January 2021

The partial molar volumes of anesthetics in lipid bilayers

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7 January 2021

The membrane volume occupied by anesthetic molecules: a reinterpretation of the erythrocyte expansion data

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7 January 2021

Temperature dependence of erythrocyte membrane expansion by alcohol anesthetics possible support for the partition theory of anesthesia

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7 January 2021

Dilatometry of dipalmitoyllecithin-cholesterol bilayers

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7 January 2021

The action of anaesthetics on phospholipid membranes

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7 January 2021

The opposing effects of pressure and general anaesthetics on the cation permeability of liposomes of varying lipid composition

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7 January 2021

Net proton-hydroxyl permeability of large unilamellar liposomes measured by an acid-base titration technique

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7 January 2021

Role of Mg2+ion-activated ATPase and a pH gradient in the storage of catecholamines in synaptic vesicles

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7 January 2021

Transport of protons and hydrochloric acid through lipid bilayer membranes

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7 January 2021

Proton and hydroxide ion permeability of phospholipid vesicles

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7 January 2021

HYDROPHOBIC INTERACTIONS IN PROTEINS: CONFORMATION CHANGES IN BOVINE SERUM ALBUMIN BELOW PH5

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7 January 2021

Binding of Large Organic Anions and Neutral Molecules by Native Bovine Serum Albumin*

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7 January 2021

The linear free-energy relationship between partition coefficients and the binding and conformational perturbation of macromolecules by small organic compounds.

1 reference

7 January 2021

The Role of Hydrophobic Bonding in the Binding of Organic Compounds by Bovine Hemoglobin*

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7 January 2021

Substrate specificity at the alkane binding sites of hemoglobin and myoglobin

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7 January 2021

Binding of Xenon to Horse Haemoglobin

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7 January 2021

Hydrophobic interactions in proteins. The alkane binding site of beta-lactoglobulins A and B

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7 January 2021

Halothane binds in the adenine-specific niche of crystalline adenylate kinase

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7 January 2021

Oxyhaemoglobin dissociation curves in vitro with and without the anaesthetics halothane and cyclopropane

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7 January 2021

Effects of alkanols and halothane on rat brain muscarinic and α-adrenergic receptors

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7 January 2021

Anaesthetics increase light emission from aequorin at constant ionised calcium.

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7 January 2021

Effect of Anaesthetics on Emission of Light by Luminous Bacteria

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7 January 2021

Effects of Anaesthetics on Luminous Bacteria

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7 January 2021

Kinetic and thermodynamic aspects of the mechanism of general anesthesia in a model system of firefly luminescence in vitro.

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7 January 2021

Identifiers

DOI

10.1038/300487A0

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1 August 2017

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