(Q34273097)

1 August 2017

title

Dynamic and static components power unfolding in topologically closed rings of a AAA+ proteolytic machine (English)

1 reference

1 August 2017

1 reference

Steven E Glynn

1

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1 August 2017

Andrew R Nager

series ordinal

2

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1 August 2017

Tania A Baker

series ordinal

3

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1 August 2017

Robert T Sauer

series ordinal

4

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1 August 2017

publication date

6 May 2012

1 reference

Nature Structural & Molecular Biology

1 August 2017

published in

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1 August 2017

volume

19

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1 August 2017

issue

6

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1 August 2017

page(s)

616-622

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Stepwise unfolding of a β barrel protein by the AAA+ ClpXP protease.

1 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372766

ClpXP, an ATP-powered unfolding and protein-degradation machine

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372766

Single-molecule protein unfolding and translocation by an ATP-fueled proteolytic machine.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372766

Structure and mechanism of the hexameric MecA-ClpC molecular machine

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372766

Crystal structure of Lon protease: molecular architecture of gated entry to a sequestered degradation chamber

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372766

Crystal structures of Bacillus subtilis Lon protease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372766

Structures of asymmetric ClpX hexamers reveal nucleotide-dependent motions in a AAA+ protein-unfolding machine

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372766

The Mechanism of ATP-Dependent Primer-Template Recognition by a Clamp Loader Complex

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372766

Structural Synergy and Molecular Crosstalk between Bacterial Helicase Loaders and Replication Initiators

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372766

AAA+ ATPases: achieving diversity of function with conserved machinery

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372766

Distinct static and dynamic interactions control ATPase-peptidase communication in a AAA+ protease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372766

Structural basis for ATP-dependent DnaA assembly and replication-origin remodeling

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372766

AAA+ proteins: have engine, will work

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372766

Partitioning between unfolding and release of native domains during ClpXP degradation determines substrate selectivity and partial processing

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372766

WebLogo: A Sequence Logo Generator

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372766

Role of the processing pore of the ClpX AAA+ ATPase in the recognition and engagement of specific protein substrates

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372766

Crystal Structure of ClpX Molecular Chaperone from Helicobacter pylori

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372766

Structure of the Rho transcription terminator: mechanism of mRNA recognition and helicase loading

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372766

An optical marker based on the UV-induced green-to-red photoconversion of a fluorescent protein

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372766

Crystal structure of ClpA, an Hsp100 chaperone and regulator of ClpAP protease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372766

ClpAP and ClpXP degrade proteins with tags located in the interior of the primary sequence

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372766

The crystal structure of the AAA domain of the ATP-dependent protease FtsH of Escherichia coli at 1.5 A resolution

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372766

Crystal structure of the processivity clamp loader gamma (gamma) complex of E. coli DNA polymerase III

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372766

Effects of protein stability and structure on substrate processing by the ClpXP unfolding and degradation machine

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372766

Functional domains of the ClpA and ClpX molecular chaperones identified by limited proteolysis and deletion analysis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372766

Crystal and solution structures of an HslUV protease-chaperone complex

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372766

The structures of HsIU and the ATP-dependent protease HsIU-HsIV

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372766

ClpA and ClpX ATPases bind simultaneously to opposite ends of ClpP peptidase to form active hybrid complexes

6 July 2018

1 reference

Rebuilt AAA + motors reveal operating principles for ATP-fuelled machines

21 January 2018

1 reference

Protein unfolding by a AAA+ protease is dependent on ATP-hydrolysis rates and substrate energy landscapes.

21 January 2018

1 reference

Diverse pore loops of the AAA+ ClpX machine mediate unassisted and adaptor-dependent recognition of ssrA-tagged substrates.

21 January 2018

1 reference

Asymmetric interactions of ATP with the AAA+ ClpX6 unfoldase: allosteric control of a protein machine.

21 January 2018

1 reference

Linkage between ATP consumption and mechanical unfolding during the protein processing reactions of an AAA+ degradation machine.

21 January 2018

1 reference

Dynamics of substrate denaturation and translocation by the ClpXP degradation machine

21 January 2018

1 reference

Nucleotide-dependent substrate handoff from the SspB adaptor to the AAA+ ClpXP protease.

21 January 2018

1 reference

C-terminal domain mutations in ClpX uncouple substrate binding from an engagement step required for unfolding.

21 January 2018

1 reference

Communication between ClpX and ClpP during substrate processing and degradation

21 January 2018

1 reference

Disulfide by Design™: a computational method for the rational design of disulfide bonds in proteins

21 January 2018

1 reference

A specificity-enhancing factor for the ClpXP degradation machine

21 January 2018

1 reference

Pore loops of the AAA+ ClpX machine grip substrates to drive translocation and unfolding

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372766

The N-terminal zinc binding domain of ClpX is a dimerization domain that modulates the chaperone function

28 October 2018

1 reference

Coupled assay of Na+,K+-ATPase activity

31 March 2020

1 reference

31 March 2020

Identifiers

DOI

10.1038/NSMB.2288

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Dimensions Publication ID

1 August 2017

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1 August 2017

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