Home
Random
Nearby
Log in
Settings
Donate
About Wikidata
Disclaimers
Search
(Q34274198)
Watch
English
Atrazine acts as an endocrine disrupter by inhibiting cAMP-specific phosphodiesterase-4
scientific article
In more languages
edit
Statements
instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PMC publication ID
4181665
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23022511%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 March 2020
title
Atrazine acts as an endocrine disrupter by inhibiting cAMP-specific phosphodiesterase-4
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
4181665
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23022511%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 March 2020
main subject
atrazine
1 reference
based on heuristic
inferred from title
author
Kristina Pogrmic-Majkic
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
4181665
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23022511%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 March 2020
author name string
Marek Kucka
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
4181665
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23022511%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 March 2020
Svetlana Fa
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMC publication ID
4181665
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23022511%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 March 2020
Stanko S Stojilkovic
series ordinal
4
1 reference
stated in
Europe PubMed Central
PMC publication ID
4181665
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23022511%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 March 2020
Radmila Kovacevic
series ordinal
5
1 reference
stated in
Europe PubMed Central
PMC publication ID
4181665
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23022511%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 March 2020
publication date
27 September 2012
1 reference
stated in
Europe PubMed Central
PMC publication ID
4181665
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23022511%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 March 2020
published in
Toxicology and Applied Pharmacology
1 reference
stated in
Europe PubMed Central
PMC publication ID
4181665
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23022511%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 March 2020
volume
265
1 reference
stated in
Europe PubMed Central
PMC publication ID
4181665
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23022511%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 March 2020
issue
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
4181665
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23022511%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 March 2020
page(s)
19-26
1 reference
stated in
Europe PubMed Central
PMC publication ID
4181665
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23022511%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 March 2020
cites work
Dependence of the excitability of pituitary cells on cyclic nucleotides
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4181665
retrieved
6 July 2018
cAMP-specific phosphodiesterases 8A and 8B, essential regulators of Leydig cell steroidogenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4181665
retrieved
6 July 2018
Upregulation of peripubertal rat Leydig cell steroidogenesis following 24 h in vitro and in vivo exposure to atrazine.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4181665
retrieved
6 July 2018
Atrazine binds to the growth hormone-releasing hormone receptor and affects growth hormone gene expression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4181665
retrieved
6 July 2018
Atrazine induces complete feminization and chemical castration in male African clawed frogs (Xenopus laevis)
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4181665
retrieved
6 July 2018
Kinetic and Structural Studies of Phosphodiesterase-8A and Implication on the Inhibitor Selectivity † ‡
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4181665
retrieved
6 July 2018
Atrazine and reproductive function: mode and mechanism of action studies.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4181665
retrieved
6 July 2018
Herbicide atrazine activates SF-1 by direct affinity and concomitant co-activators recruitments to induce aromatase expression via promoter II.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4181665
retrieved
6 July 2018
Cyclic nucleotide phosphodiesterases: molecular regulation to clinical use
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4181665
retrieved
6 July 2018
Multiple signaling pathways regulating steroidogenesis and steroidogenic acute regulatory protein expression: more complicated than we thought
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4181665
retrieved
6 July 2018
Cyclic nucleotide phosphodiesterases and their role in immunomodulatory responses: advances in the development of specific phosphodiesterase inhibitors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4181665
retrieved
6 July 2018
Evidence that atrazine and diaminochlorotriazine inhibit the estrogen/progesterone induced surge of luteinizing hormone in female Sprague-Dawley rats without changing estrogen receptor action
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4181665
retrieved
6 July 2018
A comparison of human H295R and rat R2C cell lines as in vitro screening tools for effects on aromatase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4181665
retrieved
6 July 2018
Atrazine-induced hermaphroditism at 0.1 ppb in American leopard frogs (Rana pipiens): laboratory and field evidence
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4181665
retrieved
6 July 2018
The effects of atrazine on the sexual maturation of female rats
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4181665
retrieved
6 July 2018
Atrazine effects on testosterone levels and androgen-dependent reproductive organs in peripubertal male rats.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4181665
retrieved
6 July 2018
2-Chloro-s-triazine herbicides induce aromatase (CYP19) activity in H295R human adrenocortical carcinoma cells: a novel mechanism for estrogenicity?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4181665
retrieved
6 July 2018
Atrazine disrupts the hypothalamic control of pituitary-ovarian function
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4181665
retrieved
6 July 2018
Alterations in steroidogenesis in alligators (Alligator mississippiensis) exposed naturally and experimentally to environmental contaminants
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4181665
retrieved
6 July 2018
Failure of chloro-S-triazine-derived compounds to induce estrogen receptor-mediated responses in vivo and in vitro
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4181665
retrieved
6 July 2018
Regulation of expression of steroidogenic enzymes in Leydig cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4181665
retrieved
6 July 2018
Cyclic nucleotide phosphodiesterases: functional implications of multiple isoforms
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4181665
retrieved
6 July 2018
cAMP directly facilitates Ca-induced exocytosis in bovine lactotrophs
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4181665
retrieved
6 July 2018
In vivo and in vitro effects of PCB126 and PCB153 on rat testicular androgenesis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4181665
retrieved
28 October 2018
Characterization of the hypothalamic-pituitary-adrenal axis response to atrazine and metabolites in the female rat.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4181665
retrieved
28 October 2018
Atrazine oral exposure of peripubertal male rats downregulates steroidogenesis gene expression in Leydig cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4181665
retrieved
28 October 2018
Dependence of electrical activity and calcium influx-controlled prolactin release on adenylyl cyclase signaling pathway in pituitary lactotrophs.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4181665
retrieved
28 October 2018
Cytosolic and localized inhibition of phosphodiesterase by atrazine in swine tissue homogenates
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4181665
retrieved
28 October 2018
Atrazine is a competitive inhibitor of phosphodiesterase but does not affect the estrogen receptor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4181665
retrieved
28 October 2018
Effects of atrazine on sex steroid dynamics, plasma vitellogenin concentration and gonad development in adult goldfish (Carassius auratus).
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4181665
retrieved
28 October 2018
Atrazine inhibition of testosterone production in rat males following peripubertal exposure
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4181665
retrieved
28 October 2018
Induction and inhibition of aromatase (CYP19) activity by various classes of pesticides in H295R human adrenocortical carcinoma cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4181665
retrieved
28 October 2018
Functional plasticity of cyclic AMP hydrolysis in rat adenohypophysial corticotroph cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4181665
retrieved
28 October 2018
Role of prolactin in chloro-S-triazine rat mammary tumorigenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4181665
retrieved
28 October 2018
Maternal exposure to atrazine during lactation suppresses suckling-induced prolactin release and results in prostatitis in the adult offspring.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4181665
retrieved
28 October 2018
Effects of prolactin on expression of the mRNAs encoding the immediate early genes zif/268 (NGF1-A), nur/77 (NGF1-B), c-fos and c-jun in the hypothalamus
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4181665
retrieved
28 October 2018
The effect of atrazine on puberty in male wistar rats: an evaluation in the protocol for the assessment of pubertal development and thyroid function
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/23022511
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
G-protein-coupled receptor 30 and estrogen receptor-alpha are involved in the proliferative effects induced by atrazine in ovarian cancer cells
1 reference
stated in
COCI
retrieved
30 December 2023
reference URL
https://opencitations.net/index/api/v1/citations/10.1289/EHP.11297
Identifiers
DOI
10.1016/J.TAAP.2012.09.019
1 reference
stated in
Europe PubMed Central
PMC publication ID
4181665
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23022511%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 March 2020
Fatcat ID
release_pgiw2xnwpvd5pmo45kda6qlorm
1 reference
stated in
Fatcat
reference URL
https://api.fatcat.wiki/v0/release/pgiw2xnwpvd5pmo45kda6qlorm
retrieved
24 November 2022
based on heuristic
mapped directly with Wikidata item
PMC publication ID
4181665
1 reference
stated in
Europe PubMed Central
PMC publication ID
4181665
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23022511%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 March 2020
PubMed publication ID
23022511
1 reference
stated in
Europe PubMed Central
PMC publication ID
4181665
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23022511%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 March 2020
Sitelinks
Wikipedia
(0 entries)
edit
Wikibooks
(0 entries)
edit
Wikinews
(0 entries)
edit
Wikiquote
(0 entries)
edit
Wikisource
(0 entries)
edit
Wikiversity
(0 entries)
edit
Wikivoyage
(0 entries)
edit
Wiktionary
(0 entries)
edit
Multilingual sites
(0 entries)
edit