(Q34279632)

1 August 2017

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title

Neurotrophic factors and gene therapy in spinal cord injury (English)

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ORCID Public Data File 2021

1 August 2017

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author name string

S Lacroix

series ordinal

1

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PubMed ID

11402877

1 August 2017

M H Tuszynski

series ordinal

2

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1 August 2017

1 January 2000

1 reference

Neurorehabilitation and Neural Repair

1 August 2017

1 reference

1 August 2017

14

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1 August 2017

4

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1 August 2017

265-275

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Axonal Elongation into Peripheral Nervous System "Bridges" After Central Nervous System Injury in Adult Rats

1 August 2017

1 reference

https://api.crossref.org/works/10.1177%2F154596830001400403

The nerve growth factor 35 years later

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F154596830001400403

Myelin-associated inhibitors of neurite growth and regeneration in the CNS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F154596830001400403

Neurotrophins and neuronal plasticity

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F154596830001400403

Functions of the neurotrophins during nervous system development: what the knockouts are teaching us.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F154596830001400403

Targeted mutation in the neurotrophin-3 gene results in loss of muscle sensory neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F154596830001400403

Targeted disruption of the BDNF gene perturbs brain and sensory neuron development but not motor neuron development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F154596830001400403

Severe sensory and sympathetic deficits in mice lacking neurotrophin-3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F154596830001400403

Mice lacking nerve growth factor display perinatal loss of sensory and sympathetic neurons yet develop basal forebrain cholinergic neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F154596830001400403

Role of neurotrophic factors in neuronal development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F154596830001400403

Abnormal cerebellar development and foliation in BDNF-/- mice reveals a role for neurotrophins in CNS patterning.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F154596830001400403

Nerve growth factor treatment after brain injury prevents neuronal death

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F154596830001400403

Grafting genetically modified cells to the damaged brain: restorative effects of NGF expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F154596830001400403

Recombinant human nerve growth factor infusions prevent cholinergic neuronal degeneration in the adult primate brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F154596830001400403

Central infusions of brain-derived neurotrophic factor and neurotrophin-4/5, but not nerve growth factor and neurotrophin-3, prevent loss of the cholinergic phenotype in injured adult motor neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F154596830001400403

Gene therapy in the central nervous system: the use of recombinant retroviruses

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F154596830001400403

Fibroblasts genetically modified to produce nerve growth factor induce robust neuritic ingrowth after grafting to the spinal cord

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F154596830001400403

Nerve growth factor delivery by gene transfer induces differential outgrowth of sensory, motor, and noradrenergic neurites after adult spinal cord injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F154596830001400403

Robust growth of chronically injured spinal cord axons induced by grafts of genetically modified NGF-secreting cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F154596830001400403

Functional regeneration of sensory axons into the adult spinal cord.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F154596830001400403

Nerve growth factor regulates the expression of brain-derived neurotrophic factor mRNA in the peripheral nervous system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F154596830001400403

Neurotrophin-3 enhances sprouting of corticospinal tract during development and after adult spinal cord lesion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F154596830001400403

NT-3 promotes growth of lesioned adult rat sensory axons ascending in the dorsal columns of the spinal cord.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F154596830001400403

A combination of BDNF and NT-3 promotes supraspinal axonal regeneration into Schwann cell grafts in adult rat thoracic spinal cord.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F154596830001400403

Interleukin 6 enhancement of interleukin 3-dependent proliferation of multipotential hemopoietic progenitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F154596830001400403

Neuropoietic cytokines in the hematopoietic fold

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F154596830001400403

Interleukin-6 is required in vivo for the regulation of stem cells and committed progenitors of the hematopoietic system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F154596830001400403

Neuropoietic cytokines and activin A differentially regulate the phenotype of cultured sympathetic neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F154596830001400403

Cytokines regulate the cellular phenotype of developing neural lineage species

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F154596830001400403

Regulation of gliogenesis in the central nervous system by the JAK-STAT signaling pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F154596830001400403

Neural precursor differentiation into astrocytes requires signaling through the leukemia inhibitory factor receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F154596830001400403

The neurotrophins and neuropoietic cytokines: two families of growth factors acting on neural and hematopoietic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F154596830001400403

Synthesis and localization of ciliary neurotrophic factor in the sciatic nerve of the adult rat after lesion and during regeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F154596830001400403

Cholinergic differentiation factor (CDF/LIF) promotes survival of isolated rat embryonic motoneurons in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F154596830001400403

Hypoxia/reoxygenation-mediated induction of astrocyte interleukin 6: a paracrine mechanism potentially enhancing neuron survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F154596830001400403

Cytokines promote the survival of mouse cranial sensory neurones at different developmental stages.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F154596830001400403

Local infusion of interleukin-6 attenuates the neurotoxic effects of NMDA on rat striatal cholinergic neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F154596830001400403

Coadministration of interleukin-6 (IL-6) and soluble IL-6 receptor delays progression of wobbler mouse motor neuron disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F154596830001400403

Adenoviral gene transfer of ciliary neurotrophic factor and brain-derived neurotrophic factor leads to long-term survival of axotomized motor neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F154596830001400403

Targeted disruption of gp130, a common signal transducer for the interleukin 6 family of cytokines, leads to myocardial and hematological disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F154596830001400403

Major changes in the expression of the mRNAs for cholinergic differentiation factor/leukemia inhibitory factor and its receptor after injury to adult peripheral nerves and ganglia

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F154596830001400403

Accelerated Nerve Regeneration in Mice by upregulated expression of interleukin (IL) 6 and IL-6 receptor after trauma

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F154596830001400403

Treatment of the chronically injured spinal cord with neurotrophic factors can promote axonal regeneration from supraspinal neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F154596830001400403

Neurotrophic factors increase axonal growth after spinal cord injury and transplantation in the adult rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F154596830001400403

Structural and functional impact of the transgenic expression of cytokines in the CNS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F154596830001400403

GDNF: a glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F154596830001400403

Developing motor neurons rescued from programmed and axotomy-induced cell death by GDNF

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F154596830001400403

In vivo neurotrophic effects of GDNF on neonatal and adult facial motor neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F154596830001400403

Transforming growth factor-betas in neurodegenerative disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F154596830001400403

Spinal cord repair in adult paraplegic rats: partial restoration of hind limb function

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F154596830001400403

Neuroprotective effects of basic fibroblast growth factor following spinal cord contusion injury in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F154596830001400403

Nerve growth factor-hypersecreting Schwann cell grafts augment and guide spinal cord axonal growth and remyelinate central nervous system axons in a phenotypically appropriate manner that correlates with expression of L1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F154596830001400403

Olfactory ensheathing glia: properties and function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F154596830001400403

Neuronal stem cells in the brain of adult vertebrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F154596830001400403

Survival and differentiation of adult neuronal progenitor cells transplanted to the adult brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F154596830001400403

Is there a neural stem cell in the mammalian forebrain?

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F154596830001400403

Immortalized neural progenitor cells for CNS gene transfer and repair.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F154596830001400403

Changes of nerve growth factor synthesis in nonneuronal cells in response to sciatic nerve transection

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F154596830001400403

Detection of brain-derived neurotrophic factor-like activity in fibroblasts and Schwann cells: inhibition by antibodies to NGF.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F154596830001400403

Enhanced synthesis of brain-derived neurotrophic factor in the lesioned peripheral nerve: different mechanisms are responsible for the regulation of BDNF and NGF mRNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F154596830001400403

Reciprocal Schwann cell-axon interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F154596830001400403

Identification of the major proteins that promote neuronal process outgrowth on Schwann cells in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F154596830001400403

Extrusion transplantation of Schwann cells into the adult rat thalamus induces directional host axon growth.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F154596830001400403

Transplantation of purified populations of Schwann cells into lesioned adult rat spinal cord

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F154596830001400403

Axonal regeneration into Schwann cell-seeded guidance channels grafted into transected adult rat spinal cord.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F154596830001400403

Bridging Schwann cell transplants promote axonal regeneration from both the rostral and caudal stumps of transected adult rat spinal cord.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F154596830001400403

Regrowth of axons into the distal spinal cord through a Schwann-cell-seeded mini-channel implanted into hemisected adult rat spinal cord.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F154596830001400403

Improved method for harvesting human Schwann cells from mature peripheral nerve and expansion in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F154596830001400403

Neuronal changes in the forebrain of mice following penetration by regenerating olfactory axons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F154596830001400403

Survival and subsequent regeneration of olfactory neurons after a distal axonal lesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F154596830001400403

Localization and regulation of low affinity nerve growth factor receptor expression in the rat olfactory system during development and regeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F154596830001400403

Specialized neuroglial arrangement may explain the capacity of vomeronasal axons to reinnervate central neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F154596830001400403

Neuroglial arrangements in the olfactory glomeruli of the hedgehog

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F154596830001400403

Olfactory bulb ensheathing glia: A unique cell type with axonal growth‐promoting properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F154596830001400403

Regeneration into the spinal cord of transected dorsal root axons is promoted by ensheathing glia transplants.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F154596830001400403

Repair of adult rat corticospinal tract by transplants of olfactory ensheathing cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F154596830001400403

Isolation, Characterization, and use of Stem Cells from the CNS

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F154596830001400403

Differentiation of adult hippocampus-derived progenitors into olfactory neurons in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F154596830001400403

Embryonic stem cells differentiate into oligodendrocytes and myelinate in culture and after spinal cord transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F154596830001400403

Engraftment and migration of human bone marrow stromal cells implanted in the brains of albino rats--similarities to astrocyte grafts

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F154596830001400403

Marrow stromal cells migrate throughout forebrain and cerebellum, and they differentiate into astrocytes after injection into neonatal mouse brains

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F154596830001400403

Functional Recovery of Paraplegic Rats and Motor Axon Regeneration in Their Spinal Cords by Olfactory Ensheathing Glia

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F154596830001400403

Sensory but not motor neuron deficits in mice lacking NT4 and BDNF

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F154596830001400403

Axons from CNS neurones regenerate into PNS grafts

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F154596830001400403

10.1177/154596830001400403

21 January 2018

Identifiers

DOI

1 reference

1 August 2017

1 reference

PubMed ID

11402877