(Q34295244)

1 August 2017

title

Cytoprotective effect of glucosylceramide synthase inhibition against daunorubicin-induced apoptosis in human leukemic cell lines (English)

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1 August 2017

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Solène Grazide

1

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1 August 2017

Anne-Dominique Terrisse

2

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1 August 2017

Sandra Lerouge

3

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1 August 2017

Guy Laurent

4

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1 August 2017

Jean-Pierre Jaffrézou

5

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1 August 2017

language of work or name

English

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publication date

6 February 2004

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Journal of Biological Chemistry

1 August 2017

published in

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1 August 2017

volume

279

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1 August 2017

issue

18

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1 August 2017

page(s)

18256-18261

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Ceramide in apoptosis: an overview and current perspectives

1 August 2017

cites work

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A critical evaluation of the mechanisms of action proposed for the antitumor effects of the anthracycline antibiotics adriamycin and daunorubicin

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Targeting ceramide metabolism--a strategy for overcoming drug resistance

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Expression of glucosylceramide synthase, converting ceramide to glucosylceramide, confers adriamycin resistance in human breast cancer cells

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Synthesis of Bcl-2 in response to anthracycline treatment may contribute to an apoptosis-resistant phenotype in leukemic cell lines.

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Sphingolipid metabolism in cultured fibroblasts: microscopic and biochemical studies employing a fluorescent ceramide analogue

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Signaling pathways activated by daunorubicin

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Preferential killing of multidrug-resistant KB cells by inhibitors of glucosylceramide synthase

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Glucosylceramide synthase inhibitor inhibits the action of nerve growth factor in PC12 cells.

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Intracellular translocation of fluorescent sphingolipids in cultured fibroblasts: endogenously synthesized sphingomyelin and glucocerebroside analogues pass through the Golgi apparatus en route to the plasma membrane

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Requirement for GD3 ganglioside in CD95- and ceramide-induced apoptosis.

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Trafficking of ganglioside GD3 to mitochondria by tumor necrosis factor-alpha

21 January 2018

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Lysosomal sphingomyelinase is not solicited for apoptosis signaling

21 January 2018

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Role of ceramide in mediating the inhibition of telomerase activity in A549 human lung adenocarcinoma cells

21 January 2018

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Glucosylceramide synthase does not attenuate the ceramide pool accumulating during apoptosis induced by CD95 or anti-cancer regimens

21 January 2018

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Differential chemosensitizing effect of two glucosylceramide synthase inhibitors in hepatoma cells.

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Potentiation of okadaic acid-induced ceramide elevation but not apoptosis by inhibition of glucosylceramide synthase in human neuroepithelioma cells

21 January 2018

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Altered sphingolipid metabolism in multidrug-resistant ovarian cancer cells is due to uncoupling of glycolipid biosynthesis in the Golgi apparatus.

21 January 2018

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Differential expression of sphingolipids in MRP1 overexpressing HT29 cells

21 January 2018

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Influence of ceramide metabolism on P-glycoprotein function in immature acute myeloid leukemia KG1a cells

21 January 2018

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Suppression of ceramide-mediated programmed cell death by sphingosine-1-phosphate

21 January 2018

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Sphingolipid Depletion Increases Formation of the Scrapie Prion Protein in Neuroblastoma Cells Infected with Prions

21 January 2018

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Lysosomal storage disorders. Diagnosis by ultrastructural examination of skin biopsy specimens

21 January 2018

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Involvement of sphingosine in mitochondria-dependent Fas-induced apoptosis of type II Jurkat T cells

21 January 2018

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Tumor necrosis factor induces ceramide oscillations and negatively controls sphingolipid synthases by caspases in apoptotic Kym-1 cells

21 January 2018

1 reference

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Sphingosine 1-phosphate inhibits activation of caspases that cleave poly(ADP-ribose) polymerase and lamins during Fas- and ceramide-mediated apoptosis in Jurkat T lymphocytes

21 January 2018

1 reference

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Differential regulation of sphingomyelinase and ceramidase activities by growth factors and cytokines. Implications for cellular proliferation and differentiation

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1074/JBC.M314105200

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1 August 2017

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