(Q34295777)

1 August 2017

title

Disease-related cardiac troponins alter thin filament Ca2+ association and dissociation rates. (English)

1 reference

1 August 2017

Bin Liu

1

1 reference

1 August 2017

Svetlana B Tikunova

2

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1 August 2017

Kristopher P Kline

3

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1 August 2017

Jalal K Siddiqui

4

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1 August 2017

Jonathan P Davis

5

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1 August 2017

language of work or name

English

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publication date

4 June 2012

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1 August 2017

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1 August 2017

volume

7

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1 August 2017

issue

6

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1 August 2017

page(s)

e38259

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Creative Commons Attribution 4.0 International

1 August 2017

copyright license

start time

4 June 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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Thin filament mutations: developing an integrative approach to a complex disorder

6 July 2018

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Calcium binding kinetics of troponin C strongly modulate cooperative activation and tension kinetics in cardiac muscle

6 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366952

Myocardial contraction-relaxation coupling

6 July 2018

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Phosphorylation of cardiac troponin I at protein kinase C site threonine 144 depresses cooperative activation of thin filaments

6 July 2018

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Effect of calcium-sensitizing mutations on calcium binding and exchange with troponin C in increasingly complex biochemical systems

6 July 2018

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Mutations in Troponin that cause HCM, DCM AND RCM: what can we learn about thin filament function?

6 July 2018

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Impaired relaxation is the main manifestation in transgenic mice expressing a restrictive cardiomyopathy mutation, R193H, in cardiac TnI.

6 July 2018

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Increased cross-bridge cycling kinetics after exchange of C-terminal truncated troponin I in skinned rat cardiac muscle

6 July 2018

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Ca(2+) exchange with troponin C and cardiac muscle dynamics

6 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366952

Thin filament disinhibition by restrictive cardiomyopathy mutant R193H troponin I induces Ca2+-independent mechanical tone and acute myocyte remodeling

6 July 2018

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Effects of thin and thick filament proteins on calcium binding and exchange with cardiac troponin C

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366952

Regulation of Ca2+ and Na+ in normal and failing cardiac myocytes

6 July 2018

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6 July 2018

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Mechanisms and use of calcium-sensitizing agents in the failing heart

6 July 2018

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Mutations in human cardiac troponin I that are associated with restrictive cardiomyopathy affect basal ATPase activity and the calcium sensitivity of force development

6 July 2018

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Dilated cardiomyopathy mutations in three thin filament regulatory proteins result in a common functional phenotype

6 July 2018

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Ca(2+)-desensitizing effect of a deletion mutation Delta K210 in cardiac troponin T that causes familial dilated cardiomyopathy.

6 July 2018

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Regulation of contraction in striated muscle

6 July 2018

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Cardiac troponin T mutations result in allele-specific phenotypes in a mouse model for hypertrophic cardiomyopathy

6 July 2018

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The C terminus of cardiac troponin I is essential for full inhibitory activity and Ca2+ sensitivity of rat myofibrils

6 July 2018

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Dilated and hypertrophic cardiomyopathy mutations in troponin and alpha-tropomyosin have opposing effects on the calcium affinity of cardiac thin filaments

6 July 2018

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Structural kinetics of cardiac troponin C mutants linked to familial hypertrophic and dilated cardiomyopathy in troponin complexes.

21 January 2018

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Lys184 deletion in troponin I impairs relaxation kinetics and induces hypercontractility in murine cardiac myofibrils.

21 January 2018

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Effects of the mutation R145G in human cardiac troponin I on the kinetics of the contraction-relaxation cycle in isolated cardiac myofibrils

21 January 2018

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Familial hypertrophic cardiomyopathy-related cardiac troponin C mutation L29Q affects Ca2+ binding and myofilament contractility

21 January 2018

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Identification and functional characterization of cardiac troponin I as a novel disease gene in autosomal dominant dilated cardiomyopathy

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0038259

Restrictive Cardiomyopathy

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0038259

Designing calcium-sensitizing mutations in the regulatory domain of cardiac troponin C.

21 January 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366952

Effect of hydrophobic residue substitutions with glutamine on Ca(2+) binding and exchange with the N-domain of troponin C.

28 October 2018

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Ca2+, caldesmon, and myosin light chain kinase exchange with calmodulin.

28 October 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366952

Mechanisms of altered excitation-contraction coupling in canine tachycardia-induced heart failure, I: experimental studies

28 October 2018

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12 December 2020

Increased Ca2+ affinity of cardiac thin filaments reconstituted with cardiomyopathy-related mutant cardiac troponin I

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12 December 2020

Knock-in mouse model of dilated cardiomyopathy caused by troponin mutation

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12 December 2020

The changes of the cardiac structure and function in cTnTR141W transgenic mice

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12 December 2020

A mouse model of myocardial stunning

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12 December 2020

Purification of muscle actin

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12 December 2020

21 Preparation and identification of α- and β-tropomyosins

1 reference

12 December 2020

Characterizing the response of calcium signal transducers to generated calcium transients

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0038259

Identifiers

DOI

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1 August 2017

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1 August 2017

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