(Q34296729)

1 August 2017

1 reference

title

Concentration-controlled or effect-controlled trials: useful alternatives to conventional dose-controlled trials? (English)

1 reference

1 August 2017

Grahnén A

1

1 reference

1 August 2017

Karlsson MO

series ordinal

2

1 reference

1 August 2017

publication date

1 January 2001

1 reference

Clinical Pharmacokinetics

1 August 2017

published in

1 reference

1 August 2017

volume

40

1 reference

1 August 2017

issue

5

1 reference

1 August 2017

page(s)

317-325

1 reference

Conventional compared with individualized chemotherapy for childhood acute lymphoblastic leukemia

1 August 2017

cites work

1 reference

12 December 2020

Concentration-controlled versus concentration-defined clinical trials

1 reference

12 December 2020

A randomised, concentration-controlled, comparison of standard (5-day) vs. prolonged (15-day) infusions of etoposide phosphate in small-cell lung cancer

1 reference

12 December 2020

Theophylline target concentration in severe airways obstruction - 10 or 20 mg/L? A randomised concentration-controlled trial

1 reference

12 December 2020

Relationship between plasma concentrations of 3'-deoxy-3'-fluorothymidine (alovudine) and antiretroviral activity in two concentration-controlled trials.

1 reference

12 December 2020

Pharmacokinetics and tolerability of a microemulsion formulation of cyclosporine in renal allograft recipients--a concentration-controlled comparison with the commercial formulation

1 reference

12 December 2020

Plasma concentrations of alfentanil required to supplement nitrous oxide anesthesia for general surgery.

1 reference

12 December 2020

Optimizing the science of drug development: opportunities for better candidate selection and accelerated evaluation in humans

1 reference

12 December 2020

Population pharmacodynamics: strategies for concentration-and effect-controlled clinical trials

1 reference

12 December 2020

Flunarizine for treatment of partial seizures: results of a concentration-controlled trial

1 reference

12 December 2020

Comparative efficiencies of randomized concentration- and dose-controlled clinical trials.

1 reference

12 December 2020

Theophylline serum concentration and therapeutic effect in severe acute bronchial obstruction: the optimal use of intravenously administered aminophylline

1 reference

12 December 2020

Computer-guided concentration-controlled trials in autoimmune disorders

1 reference

12 December 2020

Diuretics vs alpha-blockers for treatment of hypertension: lessons from ALLHAT. Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial

1 reference

12 December 2020

Study designs for dose-ranging

1 reference

12 December 2020

Concentration-controlled zidovudine therapy

1 reference

12 December 2020

Dose-response and concentration-response relationships: clinical and regulatory perspectives.

1 reference

12 December 2020

The effects of 4-aminopyridine in multiple sclerosis patients: results of a randomized, placebo-controlled, double-blind, concentration-controlled, crossover trial.

1 reference

12 December 2020

A randomized double-blind, multicenter plasma concentration controlled study of the safety and efficacy of oral mycophenolate mofetil for the prevention of acute rejection after kidney transplantation.

1 reference

12 December 2020

Concentration- or effect-controlled clinical trials with sparse data

1 reference

12 December 2020

Tinnitus as an Indication of Therapeutic Serum Salicylate Levels

1 reference

12 December 2020

Designs for population pharmacodynamics: value of pharmacokinetic data and population analysis

1 reference

12 December 2020

Time and theophylline concentration help explain the recovery of peak flow following acute airways obstruction. Population analysis of a randomised concentration controlled trial

1 reference

12 December 2020

Concentration-controlled trials. What does the future hold?

1 reference

12 December 2020

The randomized concentration-controlled trial: An evaluation of its sample size efficiency

1 reference

12 December 2020

Predicting effective drug concentrations for individual patients. Determinants of pharmacodynamic variability

1 reference

12 December 2020

Randomized, trough blood cyclosporine concentration-controlled trial to compare the pharmacodynamics of Sandimmune and Neoral in de novo lung transplant recipients

1 reference

12 December 2020

Comparison of standard and low serum levels of lithium for maintenance treatment of bipolar disorder

1 reference

12 December 2020

Learning versus confirming in clinical drug development

1 reference

12 December 2020

10.2165/00003088-200140050-00001

Identifiers

DOI

1 reference

Dimensions Publication ID

1 August 2017

1022243616

0 references

1 reference