(Q34305220)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20739511%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

title

An APPL1-AMPK signaling axis mediates beneficial metabolic effects of adiponectin in the heart (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20739511%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20739511%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

author name string

Xiangping Fang

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20739511%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

Rengasamy Palanivel

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20739511%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

Justin Cresser

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20739511%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

Kristin Schram

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20739511%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

Riya Ganguly

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20739511%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

Farah S L Thong

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20739511%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

Joseph Tuinei

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20739511%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

Aimin Xu

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20739511%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

Gary Sweeney

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20739511%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

publication date

24 August 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20739511%20AND%20SRC:MED&resulttype=core&format=json

American Journal of Physiology - Endocrinology and Metabolism

11 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20739511%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

volume

299

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20739511%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

issue

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20739511%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

page(s)

E721-9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20739511%20AND%20SRC:MED&resulttype=core&format=json

Adiponectin activates AMP-activated protein kinase in muscle cells via APPL1/LKB1-dependent and phospholipase C/Ca2+/Ca2+/calmodulin-dependent protein kinase kinase-dependent pathways

11 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2980363

Mechanisms for increased myocardial fatty acid utilization following short-term high-fat feeding

6 July 2018

1 reference

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Cardiac remodeling in obesity.

6 July 2018

1 reference

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Molecular mechanisms for myocardial mitochondrial dysfunction in the metabolic syndrome

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2980363

The physiological and pathophysiological role of adiponectin and adiponectin receptors in the peripheral tissues and CNS.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2980363

Adiponectin and its receptors are expressed in adult ventricular cardiomyocytes and upregulated by activation of peroxisome proliferator-activated receptor gamma

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2980363

Cardioprotection by adiponectin

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2980363

APPL1 binds to adiponectin receptors and mediates adiponectin signalling and function

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2980363

Hyperglycemia- and hyperinsulinemia-induced alteration of adiponectin receptor expression and adiponectin effects in L6 myoblasts

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2980363

Reduced mitochondrial oxidative capacity and increased mitochondrial uncoupling impair myocardial energetics in obesity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2980363

Adiponectin protects against myocardial ischemia-reperfusion injury through AMPK- and COX-2-dependent mechanisms

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2980363

Reduced cardiac efficiency and altered substrate metabolism precedes the onset of hyperglycemia and contractile dysfunction in two mouse models of insulin resistance and obesity.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2980363

Adiponectin is synthesized and secreted by human and murine cardiomyocytes.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2980363

Regulation of fatty acid uptake and metabolism in L6 skeletal muscle cells by resistin

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2980363

Myocardial substrate metabolism in the normal and failing heart

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2980363

Exacerbation of heart failure in adiponectin-deficient mice due to impaired regulation of AMPK and glucose metabolism

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2980363

Adiponectin and adiponectin receptors

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2980363

Diabetic cardiomyopathy: recent evidence from mouse models of type 1 and type 2 diabetes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2980363

Adiponectin-mediated modulation of hypertrophic signals in the heart

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2980363

LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2980363

Cardiac lipid accumulation associated with diastolic dysfunction in obese mice.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2980363

Contraction-Induced Fatty Acid Translocase/CD36 Translocation in Rat Cardiac Myocytes Is Mediated Through AMP-Activated Protein Kinase Signaling

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2980363

Cloning of adiponectin receptors that mediate antidiabetic metabolic effects

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2980363

Enhanced muscle fat oxidation and glucose transport by ACRP30 globular domain: acetyl-CoA carboxylase inhibition and AMP-activated protein kinase activation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2980363

The adipocyte-secreted protein Acrp30 enhances hepatic insulin action

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2980363

The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2980363

A novel mouse model of lipotoxic cardiomyopathy

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2980363

Proteolytic cleavage product of 30-kDa adipocyte complement-related protein increases fatty acid oxidation in muscle and causes weight loss in mice

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2980363

Lipotoxic heart disease in obese rats: implications for human obesity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2980363

Regulation of fatty acid oxidation of the heart by MCD and ACC during contractile stimulation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2980363

Age-dependent changes in metabolism, contractile function, and ischemic sensitivity in hearts from db/db mice

6 July 2018

1 reference

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Mitochondrial energetics in the heart in obesity-related diabetes: direct evidence for increased uncoupled respiration and activation of uncoupling proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00086.2010

Insulin stimulates fatty acid transport by regulating expression of FAT/CD36 but not FABPpm

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00086.2010

Adiponectin-induced endothelial nitric oxide synthase activation and nitric oxide production are mediated by APPL1 in endothelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00086.2010

Activation of PPARgamma enhances myocardial glucose oxidation and improves contractile function in isolated working hearts of ZDF rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00086.2010

Role of the nitric oxide pathway in AMPK-mediated glucose uptake and GLUT4 translocation in heart muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00086.2010

Insulin stimulates long-chain fatty acid utilization by rat cardiac myocytes through cellular redistribution of FAT/CD36.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00086.2010

Impaired cardiac efficiency and increased fatty acid oxidation in insulin-resistant ob/ob mouse hearts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00086.2010

gAd-globular head domain of adiponectin increases fatty acid oxidation in newborn rabbit hearts

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00086.2010

Unraveling the temporal pattern of diet-induced insulin resistance in individual organs and cardiac dysfunction in C57BL/6 mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00086.2010

Effect of obesity and insulin resistance on myocardial substrate metabolism and efficiency in young women

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00086.2010

Intramyocardial lipid accumulation in the failing human heart resembles the lipotoxic rat heart.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00086.2010

Adiponectin sensitizes insulin signaling by reducing p70 S6 kinase-mediated serine phosphorylation of IRS-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00086.2010

Impact of altered substrate utilization on cardiac function in isolated hearts from Zucker diabetic fatty rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00086.2010

Impaired long-chain fatty acid oxidation and contractile dysfunction in the obese Zucker rat heart.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00086.2010

Acetyl-CoA carboxylase control of fatty acid oxidation in hearts from hibernating Richardson's ground squirrels

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20739511

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Adiponectin increases fatty acid oxidation in skeletal muscle cells by sequential activation of AMP-activated protein kinase, p38 mitogen-activated protein kinase, and peroxisome proliferator-activated receptor alpha

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20739511

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Globular and full-length forms of adiponectin mediate specific changes in glucose and fatty acid uptake and metabolism in cardiomyocytes

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20739511

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1152/AJPENDO.00086.2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20739511%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20739511%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

1 reference