(Q34313513)

1 August 2017

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title

Circadian rhythm sleep disorders: pathophysiology and potential approaches to management (English)

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1 August 2017

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Zisapel N

1

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1 August 2017

1 January 2001

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1 August 2017

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1 August 2017

15

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1 August 2017

4

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1 August 2017

311-328

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https://scigraph.springernature.com/pub.10.2165/00023210-200115040-00005

1 August 2017

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12 December 2020

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Adapting to phase shifts, II. Effects of melatonin and conflicting light treatment

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12 December 2020

Can melatonin alleviate jet lag?

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Resetting the biological clock: mediation of nocturnal CREB phosphorylation via light, glutamate, and nitric oxide

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Effects of melatonin in two individuals with Alzheimer's disease

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Nocturnal melatonin onset is phase locked to the primary sleep gate.

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Effect of melatonin on jet lag after long haul flights

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Improvement of sleep quality in elderly people by controlled-release melatonin.

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12 December 2020

Continuous measurement of temperature in non-24 hour sleep-wake syndrome

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12 December 2020

Melatonin and jet lag: confirmatory result using a simplified protocol

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12 December 2020

Melatonin effect on daytime sleep in men: suppression of EEG low frequency activity and enhancement of spindle frequency activity

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12 December 2020

Concentrations of serotonin and its related substances in the cerebrospinal fluid in patients with Alzheimer type dementia

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12 December 2020

Effect of melatonin replacement on serum hormone rhythms in a patient lacking endogenous melatonin.

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12 December 2020

Monozygotic twins with Alzheimer's disease treated with melatonin: Case report.

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12 December 2020

The effect of melatonin on normal sleep.

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12 December 2020

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12 December 2020

Peripheral heat loss: a predictor of the hypothermic response to melatonin administration in young and older women.

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12 December 2020

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Daytime melatonin administration enhances sleepiness and theta/alpha activity in the waking EEG

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12 December 2020

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12 December 2020

Complex effects of melatonin on human circadian rhythms in constant dim light

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12 December 2020

Predictors of subjective sleepiness induced by melatonin administration

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12 December 2020

Correction of non-24-hour sleep/wake cycle by melatonin in a blind retarded boy.

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12 December 2020

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12 December 2020

Circadian rhythm disorders in sleep-waking and body temperature in elderly patients with dementia and their treatment.

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12 December 2020

Decreased melatonin levels in postmortem cerebrospinal fluid in relation to aging, Alzheimer's disease, and apolipoprotein E-epsilon4/4 genotype.

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12 December 2020

Melatonin administration can entrain the free-running circadian system of blind subjects

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12 December 2020

The influence of light on circadian rhythms

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12 December 2020

The importance of timing in melatonin administration in a blind man

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12 December 2020

The modulatory effect of melatonin on the dopamine-glutamate interaction in the anterior hypothalamus during ageing.

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12 December 2020

Effect of melatonin on sleep microstructure: preliminary results in healthy subjects.

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12 December 2020

Selective MT2 melatonin receptor antagonists block melatonin-mediated phase advances of circadian rhythms

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12 December 2020

Nocturnal exercise phase delays circadian rhythms of melatonin and thyrotropin secretion in normal men

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12 December 2020

Association of sleep-wake habits in older people with changes in output of circadian pacemaker

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12 December 2020

Effects of irregular versus regular sleep schedules on performance, mood and body temperature.

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12 December 2020

Psychopharmacological effects of melatonin in mouse and rat.

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12 December 2020

Daily variation in the concentration of melatonin and 5-methoxytryptophol in the human pineal gland: effect of age and Alzheimer's disease.

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12 December 2020

Abnormal circadian rhythms of plasma melatonin and body temperature in the delayed sleep phase syndrome

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12 December 2020

Melatonin as a chronobiotic: treatment of circadian desynchrony in night workers and the blind

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12 December 2020

Treatment of a case of advanced sleep phase syndrome by phase advance chronotherapy.

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12 December 2020

Jet lag: clinical features, validation of a new syndrome-specific scale, and lack of response to melatonin in a randomized, double-blind trial.

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12 December 2020

Improving adaptation to simulated night shift: timed exposure to bright light versus daytime melatonin administration.

1 reference

12 December 2020

Vitamin B12 treatment for sleep-wake rhythm disorders

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12 December 2020

Melatonin and delayed sleep phase syndrome: ambulatory polygraphic evaluation.

1 reference

12 December 2020

Inhibition by melatonin of dopamine release from rat hypothalamus in vitro: variations with sex and the estrous cycle.

1 reference

12 December 2020

Photic induction of mPer1 and mPer2 in cry-deficient mice lacking a biological clock

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12 December 2020

Molecular dissection of two distinct actions of melatonin on the suprachiasmatic circadian clock.

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12 December 2020

Delayed sleep phase syndrome: A placebo-controlled cross-over study on the effects of melatonin administered five hours before the individual dim light melatonin onset.

1 reference

12 December 2020

The suprachiasmatic nucleus of the human brain in relation to sex, age and senile dementia.

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12 December 2020

Later endogenous circadian temperature nadir relative to an earlier wake time in older people.

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12 December 2020

Chronobiology of aging: temperature, sleep-wake rhythms and entrainment.

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12 December 2020

Alterations in Nocturnal Serum Melatonin Levels In Humans With Growth and Aging*

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12 December 2020

Circadian rhythm abnormalities in totally blind people: incidence and clinical significance

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12 December 2020

Improvement of sleep quality by melatonin

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12 December 2020

Disturbance of sleep in blindness.

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12 December 2020

Vitamin B12 treatment for delayed sleep phase syndrome: a multi-center double-blind study.

1 reference

12 December 2020

Melatonin directly resets the rat suprachiasmatic circadian clock in vitro

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12 December 2020

Long-term melatonin treatment in blind children and young adults with circadian sleep-wake disturbances.

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12 December 2020

Are age differences in sleep due to phase differences in the output of the circadian timing system?

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12 December 2020

Human plasma melatonin and urinary 6-sulphatoxy melatonin: studies in natural annual photoperiod and in extended darkness.

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12 December 2020

The role of melatonin and light in the human circadian system.

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12 December 2020

Melatonin: daily cycle in plasma and cerebrospinal fluid of calves

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12 December 2020

Entrainment of free-running circadian rhythms by melatonin in blind people

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12 December 2020

Prevalence of sleep/wake disorders in persons with blindness

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12 December 2020

Melatonin replacement therapy of elderly insomniacs.

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12 December 2020

Melatonin shifts human circadian rhythms according to a phase-response curve

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12 December 2020

Contemporaneous melatonin administration modifies the circadian response to nocturnal bright light stimuli.

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12 December 2020

Circadian rhythms of melatonin and cortisol in aging.

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12 December 2020

Bright light treatment for sleep-wake disturbances in aged individuals with dementia.

1 reference

12 December 2020

Exposure to bright light and darkness to treat physiologic maladaptation to night work

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12 December 2020

Treatment with beta-adrenoceptor blockers reduces plasma melatonin concentration

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12 December 2020

Chronotherapy: resetting the circadian clocks of patients with delayed sleep phase insomnia

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12 December 2020

Neural pathways and neurotransmitters affecting melatonin synthesis.

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12 December 2020

Effects of a four-day nocturnal melatonin treatment on the 24 h plasma melatonin, cortisol and prolactin profiles in humans

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12 December 2020

Sleepiness and shift work: field studies.

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12 December 2020

Clonidine reduces plasma melatonin levels

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12 December 2020

Melatonin in circadian sleep disorders in the blind.

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12 December 2020

Periodic fatigue symptoms due to desynchronization in a patient with non-24-h sleep-wake syndrome

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12 December 2020

Regulation of melatonin's activity in the female rat brain by estradiol: effects on neurotransmitter release and on iodomelatonin binding sites.

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12 December 2020

Suprachiasmatic nucleus: the brain's circadian clock

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12 December 2020

Bright light treatment of behavioral and sleep disturbances in patients with Alzheimer's disease

1 reference

12 December 2020

Neuroendocrine rhythms and sleep in aging men.

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12 December 2020

Melatonin Administration to Blind People: Phase Advances and Entrainment

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12 December 2020

Melatonin serum levels and metabolic clearance rate in patients with liver cirrhosis

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12 December 2020

Triazolam and Melatonin Effects on Cardiac Autonomic Function During Sleep

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12 December 2020

Do plasma melatonin concentrations decline with age?

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12 December 2020

Non-24-hour sleep-wake syndrome in a sighted man: circadian rhythm studies and efficacy of melatonin treatment.

1 reference

12 December 2020

Changes in the sleep and waking EEGs of nondemented and demented elderly subjects.

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12 December 2020

Roles of intensity and duration of nocturnal exercise in causing phase delays of human circadian rhythms

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12 December 2020

Melatonin efficacy in aviation missions requiring rapid deployment and night operations.

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12 December 2020

Alleviation of jet lag by melatonin: preliminary results of controlled double blind trial

1 reference

12 December 2020

Light suppresses melatonin secretion in humans

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12 December 2020

Influence of Melatonin Treatment on Human Circadian Rhythmicity before and after a Simulated 9-Hr Time Shift

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12 December 2020

The role of melatonin and circadian phase in age-related sleep-maintenance insomnia: assessment in a clinical trial of melatonin replacement

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12 December 2020

Can melatonin improve shift workers' tolerance of the night shift? Some preliminary findings.

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12 December 2020

Circadian temperature variation in healthy aged and in Alzheimer's disease.

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12 December 2020

Effect of inducing nocturnal serum melatonin concentrations in daytime on sleep, mood, body temperature, and performance

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12 December 2020

Synchronization of mammalian circadian rhythms by melatonin.

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12 December 2020

A double-blind trial of melatonin as a treatment for jet lag in international cabin crew.

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12 December 2020

Melatonin: a principal neuroimmunoregulatory and anti-stress hormone: its anti-aging effects

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12 December 2020

Melatonin, sleep, aging, and the health protection branch

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12 December 2020

Bright light resets the human circadian pacemaker independent of the timing of the sleep-wake cycle

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12 December 2020

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12 December 2020

Characteristics of circadian rhythms in human functions.

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12 December 2020

The salivary melatonin diurnal rhythm may be abolished after transmeridian flights in an eastward but not a westward direction

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12 December 2020

Is there an intrinsic period of the circadian clock?

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12 December 2020

Bioavailability of oral melatonin in humans.

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12 December 2020

Urinary 6-sulfatoxymelatonin excretion and aging: new results and a critical review of the literature.

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12 December 2020

Pineal Melatonin: Cell Biology of Its Synthesis and of Its Physiological Interactions*

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12 December 2020

Molecular bases for circadian clocks

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12 December 2020

Melatonin stabilises sleep onset time in a blind man without entrainment of cortisol or temperature rhythms

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12 December 2020

Sleep disorders in children with blindness.

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12 December 2020

Hypnotic and hypothermic effects of melatonin on daytime sleep in humans: lack of antagonism by flumazenil

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12 December 2020

Functional link between distal vasodilation and sleep-onset latency?

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12 December 2020

The pineal gland: a neurochemical transducer

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12 December 2020

The melatonin rhythm-generating enzyme: molecular regulation of serotonin N-acetyltransferase in the pineal gland

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12 December 2020

Acute administration of triazolam for the daytime sleep of rotating shift workers.

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12 December 2020

Mammalian pineal melatonin: a clock for all seasons

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12 December 2020

The brain, circadian rhythms, and clock genes

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12 December 2020

Effect of melatonin in selected populations of sleep-disturbed patients.

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12 December 2020

Facilitation of benzodiazepine discontinuation by melatonin: a new clinical approach

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12 December 2020

Bright light treatment used for adaptation to night work and re-adaptation back to day life. A field study at an oil platform in the North Sea.

1 reference

12 December 2020

10.2165/00023210-200115040-00005

Identifiers

DOI

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PubMed ID

11463135

Dimensions Publication ID

1 August 2017

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1 reference

PubMed ID

11463135