(Q34318405)

1 August 2017

title

PPARγ is an E3 ligase that induces the degradation of NFκB/p65. (English)

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1 August 2017

Yongzhong Hou

1

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1 August 2017

France Moreau

series ordinal

2

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1 August 2017

Kris Chadee

series ordinal

3

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1 August 2017

language of work or name

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1 January 2012

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1 August 2017

published in

Nature Communications

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1 August 2017

volume

3

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1 August 2017

page(s)

1300

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Commensal anaerobic gut bacteria attenuate inflammation by regulating nuclear-cytoplasmic shuttling of PPAR-gamma and RelA.

1 August 2017

cites work

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12 December 2020

NF-kappaB in cancer: a marked target

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12 December 2020

Series introduction: the transcription factor NF-kappaB and human disease

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12 December 2020

Utility of the housekeeping genes 18S rRNA, beta-actin and glyceraldehyde-3-phosphate-dehydrogenase for normalization in real-time quantitative reverse transcriptase-polymerase chain reaction analysis of gene expression in human T lymphocytes

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12 December 2020

PPAR-gamma receptor ligands: novel therapy for pituitary adenomas

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12 December 2020

Colorectal cancer expression of peroxisome proliferator-activated receptor gamma (PPARG, PPARgamma) is associated with good prognosis

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12 December 2020

The gene product Murr1 restricts HIV-1 replication in resting CD4+ lymphocytes

1 reference

12 December 2020

Characteristics of the peroxisome proliferator activated receptor gamma (PPARgamma) ligand induced apoptosis in colon cancer cells

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12 December 2020

Nuclear ubiquitin ligases, NF-kappaB degradation, and the control of inflammation

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12 December 2020

Degradation of promoter-bound p65/RelA is essential for the prompt termination of the nuclear factor kappaB response

1 reference

12 December 2020

Identification, characterization, and tissue distribution of human peroxisome proliferator-activated receptor (PPAR) isoforms PPARgamma2 versus PPARgamma1 and activation with retinoid X receptor agonists and antagonists

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12 December 2020

Epithelial NF-kappaB maintains host gut microflora homeostasis

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12 December 2020

Certain pairs of ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s) synthesize nondegradable forked ubiquitin chains containing all possible isopeptide linkages.

1 reference

12 December 2020

Entamoeba histolytica cysteine proteinase 5 binds integrin on colonic cells and stimulates NFkappaB-mediated pro-inflammatory responses

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12 December 2020

Nuclear factor-kappaB signaling and ezrin are essential for L1-mediated metastasis of colon cancer cells.

1 reference

12 December 2020

A SUMOylation-dependent pathway mediates transrepression of inflammatory response genes by PPAR-gamma

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12 December 2020

Quantitative proteomics reveals the function of unconventional ubiquitin chains in proteasomal degradation

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12 December 2020

Substrate targeting in the ubiquitin system

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12 December 2020

MAPK kinases as nucleo-cytoplasmic shuttles for PPARgamma

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12 December 2020

Rosiglitazone: a new therapy for Type 2 diabetes

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12 December 2020

GCN5 is a required cofactor for a ubiquitin ligase that targets NF-kappaB/RelA

1 reference

12 December 2020

Regulation of NF-kappaB signaling by Pin1-dependent prolyl isomerization and ubiquitin-mediated proteolysis of p65/RelA.

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12 December 2020

Anti-inflammatory actions of PPAR ligands: new insights on cellular and molecular mechanisms

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12 December 2020

RING finger proteins: mediators of ubiquitin ligase activity

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12 December 2020

COMMD1 promotes the ubiquitination of NF-kappaB subunits through a cullin-containing ubiquitin ligase

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12 December 2020

Polyubiquitin chains: polymeric protein signals

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12 December 2020

An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor gamma (PPAR gamma)

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12 December 2020

Physiological and therapeutic roles of peroxisome proliferator-activated receptors

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12 December 2020

Troglitazone Antagonizes Tumor Necrosis Factor-α-induced Reprogramming of Adipocyte Gene Expression by Inhibiting the Transcriptional Regulatory Functions of NF-κB

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12 December 2020

RING domain E3 ubiquitin ligases

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12 December 2020

NF-kappaB functions as a tumour promoter in inflammation-associated cancer

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12 December 2020

PDLIM2-mediated termination of transcription factor NF-kappaB activation by intranuclear sequestration and degradation of the p65 subunit

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12 December 2020

Synergy between PPARgamma ligands and platinum-based drugs in cancer

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12 December 2020

Oxidized low density lipoprotein inhibits interleukin-12 production in lipopolysaccharide-activated mouse macrophages via direct interactions between peroxisome proliferator-activated receptor-gamma and nuclear factor-kappa B

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12 December 2020

PPARgamma1 attenuates cytosol to membrane translocation of PKCalpha to desensitize monocytes/macrophages.

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12 December 2020

Loss-of-Function Mutations in PPARγ Associated with Human Colon Cancer

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12 December 2020

Signaling to NF-kappaB

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12 December 2020

Identifiers

DOI

10.1038/NCOMMS2270

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Dimensions Publication ID

1 August 2017

0 references

1010152058

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