(Q34319260)

1 August 2017

Exaggerated translation causes synaptic and behavioural aberrations associated with autism (English)

1 reference

Eukaryotic translation initiation factor 4E

1 August 2017

0 references

1 reference

Eukaryotic translation initiation factor 4, gamma 1

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author name string

Emanuela Santini

1

1 reference

1 August 2017

Thu N Huynh

2

1 reference

1 August 2017

Andrew F MacAskill

3

1 reference

1 August 2017

Adam G Carter

4

1 reference

1 August 2017

Philippe Pierre

5

1 reference

1 August 2017

Davide Ruggero

6

1 reference

1 August 2017

Hanoch Kaphzan

7

1 reference

1 August 2017

Eric Klann

8

1 reference

1 August 2017

language of work or name

English

0 references

publication date

23 December 2012

1 reference

1 August 2017

1 reference

1 August 2017

493

1 reference

1 August 2017

7432

1 reference

1 August 2017

411-415

1 reference

https://scigraph.springernature.com/pub.10.1038/nature11782

1 August 2017

0 references

cites work

Disrupted Homer scaffolds mediate abnormal mGluR5 function in a mouse model of fragile X syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548017

Mutations causing syndromic autism define an axis of synaptic pathophysiology

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548017

High-throughput, detailed, cell-specific neuroanatomy of dendritic spines using microinjection and confocal microscopy

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548017

Impaired social interactions and motor learning skills in tuberous sclerosis complex model mice expressing a dominant/negative form of tuberin

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548017

Neocortical excitation/inhibition balance in information processing and social dysfunction

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548017

Shank3 mutant mice display autistic-like behaviours and striatal dysfunction

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548017

Inhibition of the interactions between eukaryotic initiation factors 4E and 4G impairs long-term associative memory consolidation but not reconsolidation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548017

GABAB receptors modulate NMDA receptor calcium signals in dendritic spines

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548017

Neuroligin-1 deletion results in impaired spatial memory and increased repetitive behavior

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548017

Dysregulation of mTOR signaling in fragile X syndrome

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548017

Probing compulsive and impulsive behaviors, from animal models to endophenotypes: a narrative review

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548017

Deregulation of EIF4E: a novel mechanism for autism.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548017

The genetic and neurobiologic compass points toward common signaling dysfunctions in autism spectrum disorders

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548017

Pharmacological inhibition of mTORC1 suppresses anatomical, cellular, and behavioral abnormalities in neural-specific Pten knock-out mice

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548017

Marble burying reflects a repetitive and perseverative behavior more than novelty-induced anxiety

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548017

Removal of FKBP12 enhances mTOR-Raptor interactions, LTP, memory, and perseverative/repetitive behavior

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548017

The Autistic Neuron: Troubled Translation?

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548017

Autism: Definition, Neurobiology, Screening, Diagnosis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548017

Reversal of learning deficits in a Tsc2+/- mouse model of tuberous sclerosis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548017

Correction of fragile X syndrome in mice.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548017

The GTP-binding protein Rhes modulates dopamine signalling in striatal medium spiny neurons

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548017

A neuroligin-3 mutation implicated in autism increases inhibitory synaptic transmission in mice

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548017

Mapping autism risk loci using genetic linkage and chromosomal rearrangements

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548017

Small-molecule inhibition of the interaction between the translation initiation factors eIF4E and eIF4G

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548017

Behavioral alterations in mice lacking the translation repressor 4E-BP2

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548017

Dynamic translational and proteasomal regulation of fragile X mental retardation protein controls mGluR-dependent long-term depression

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548017

Pten regulates neuronal arborization and social interaction in mice

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548017

Sociability and preference for social novelty in five inbred strains: an approach to assess autistic-like behavior in mice

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548017

A genomewide screen of 345 families for autism-susceptibility loci

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548017

Hierarchical phosphorylation of the translation inhibitor 4E-BP1

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548017

Long-term synaptic depression in the striatum: physiological and pharmacological characterization

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548017

The translation factor eIF-4E promotes tumor formation and cooperates with c-Myc in lymphomagenesis

6 July 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE11782

Regulation of translation initiation by FRAP/mTOR

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE11782

SUnSET, a nonradioactive method to monitor protein synthesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE11782

Altered dopaminergic innervation and amphetamine response in adult Otx2 conditional mutant mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE11782

Basal ganglia shapes predict social, communication, and motor dysfunctions in boys with autism spectrum disorder.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548017

Postadolescent changes in regional cerebral protein synthesis: an in vivo study in the FMR1 null mouse.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548017

Role for Rapid Dendritic Protein Synthesis in Hippocampal mGluR-Dependent Long-Term Depression

28 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23263185

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NATURE11782

1 reference

Dimensions Publication ID

1 August 2017

0 references

1 reference

1 August 2017

1 reference