(Q34321178)

1 August 2017

title

Delayed recovery of skeletal muscle mass following hindlimb immobilization in mTOR heterozygous mice (English)

1 reference

1 August 2017

1 reference

Susan M Lang

1

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1 August 2017

Abid A Kazi

series ordinal

2

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1 August 2017

Ly Hong-Brown

series ordinal

3

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1 August 2017

Charles H Lang

series ordinal

4

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1 August 2017

language of work or name

English

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publication date

22 June 2012

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1 August 2017

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1 August 2017

volume

7

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1 August 2017

issue

6

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1 August 2017

page(s)

e38910

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Creative Commons Attribution 4.0 International

1 August 2017

copyright license

start time

22 June 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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Phosphoproteomic analysis identifies Grb10 as an mTORC1 substrate that negatively regulates insulin signaling

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Deptor knockdown enhances mTOR Activity and protein synthesis in myocytes and ameliorates disuse muscle atrophy

6 July 2018

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Losartan restores skeletal muscle remodeling and protects against disuse atrophy in sarcopenia

6 July 2018

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mTor signaling in skeletal muscle during sepsis and inflammation: where does it all go wrong?

6 July 2018

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Skeletal muscle mass recovery from atrophy in IL-6 knockout mice

6 July 2018

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The role and regulation of MAFbx/atrogin-1 and MuRF1 in skeletal muscle atrophy.

6 July 2018

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Targeted ablation of TRAF6 inhibits skeletal muscle wasting in mice.

6 July 2018

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Impact of viral-mediated IGF-I gene transfer on skeletal muscle following cast immobilization

6 July 2018

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Modulation of muscle atrophy, fatigue and MLC phosphorylation by MuRF1 as indicated by hindlimb suspension studies on MuRF1-KO mice

6 July 2018

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BCATm deficiency ameliorates endotoxin-induced decrease in muscle protein synthesis and improves survival in septic mice.

6 July 2018

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Skeletal muscle protein balance in mTOR heterozygous mice in response to inflammation and leucine

6 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382153

The TWEAK-Fn14 system is a critical regulator of denervation-induced skeletal muscle atrophy in mice.

6 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382153

Skeletal muscle loss: cachexia, sarcopenia, and inactivity

6 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382153

Minireview: Mechano-growth factor: a putative product of IGF-I gene expression involved in tissue repair and regeneration

6 July 2018

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Muscle inactivation of mTOR causes metabolic and dystrophin defects leading to severe myopathy

6 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382153

Limb immobilization induces a coordinate down-regulation of mitochondrial and other metabolic pathways in men and women

6 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382153

Local insulin-like growth factor I prevents sepsis-induced muscle atrophy

6 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382153

The PI3K/Akt/mTOR pathway in innate immune cells: emerging therapeutic applications

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382153

The involvement of the ubiquitin proteasome system in human skeletal muscle remodelling and atrophy.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382153

The ubiquitin-proteasome and the mitochondria-associated apoptotic pathways are sequentially downregulated during recovery after immobilization-induced muscle atrophy

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382153

Nuclear factor-kappa B signaling in skeletal muscle atrophy.

6 July 2018

1 reference

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Calpain activity and muscle wasting in sepsis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382153

Acute alcohol intoxication increases atrogin-1 and MuRF1 mRNA without increasing proteolysis in skeletal muscle

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382153

Assessing effects of alcohol consumption on protein synthesis in striated muscles

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382153

FoxO3 coordinately activates protein degradation by the autophagic/lysosomal and proteasomal pathways in atrophying muscle cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382153

Regulation of muscle protein synthesis during sepsis and inflammation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382153

Protein kinase B/Akt: a nexus of growth factor and cytokine signaling in determining muscle mass

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382153

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382153

The ABCs of IGF-I isoforms: impact on muscle hypertrophy and implications for repair

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382153

Coordination of metabolic plasticity in skeletal muscle

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382153

mTOR and S6K1 mediate assembly of the translation preinitiation complex through dynamic protein interchange and ordered phosphorylation events

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382153

Mechanical signals, IGF-I gene splicing, and muscle adaptation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382153

Skeletal muscle cytokines: regulation by pathogen-associated molecules and catabolic hormones

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382153

Muscle expression of a local Igf-1 isoform protects motor neurons in an ALS mouse model

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382153

Inflammatory processes in muscle injury and repair

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382153

Disruption of the mouse mTOR gene leads to early postimplantation lethality and prohibits embryonic stem cell development

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382153

IKKbeta/NF-kappaB activation causes severe muscle wasting in mice

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382153

mTOR is essential for growth and proliferation in early mouse embryos and embryonic stem cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382153

Regrowth of skeletal muscle atrophied from inactivity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382153

Atrophy responses to muscle inactivity. II. Molecular markers of protein deficits

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382153

Regulation of insulin-like growth factor-I in skeletal muscle and muscle cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382153

The mammalian target of rapamycin (mTOR) partner, raptor, binds the mTOR substrates p70 S6 kinase and 4E-BP1 through their TOR signaling (TOS) motif

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382153

mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382153

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382153

Atrogin-1, a muscle-specific F-box protein highly expressed during muscle atrophy

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382153

Akt/mTOR pathway is a crucial regulator of skeletal muscle hypertrophy and can prevent muscle atrophy in vivo

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382153

Identification of ubiquitin ligases required for skeletal muscle atrophy

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382153

Localized Igf-1 transgene expression sustains hypertrophy and regeneration in senescent skeletal muscle

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382153

Measurement of tissue protein synthesis rates in vivo: a critical analysis of contrasting methods

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382153

Regrowth of atrophied skeletal muscle in adult rats after ending immobilization

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382153

Early change in skeletal muscle protein synthesis after limb immobilization of rats

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382153

Effects of 3 days unloading on molecular regulators of muscle size in humans

6 July 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0038910

Electromechanical stimulation ameliorates inactivity-induced adaptations in the medial gastrocnemius of adult rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0038910

Hindlimb casting decreases muscle mass in part by proteasome-dependent proteolysis but independent of protein synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0038910

Muscle proteins during 60-day bedrest in women: impact of exercise or nutrition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0038910

Immobilization induces anabolic resistance in human myofibrillar protein synthesis with low and high dose amino acid infusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0038910

Effect of hindlimb suspension on the functional properties of slow and fast soleus fibers from three strains of mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0038910

Alcohol accelerates loss of muscle and impairs recovery of muscle mass resulting from disuse atrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0038910

Tumor necrosis factor-alpha promotes the accumulation of neutrophils and macrophages in skeletal muscle.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0038910

A novel hindlimb immobilization procedure for studying skeletal muscle atrophy and recovery in mouse.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0038910

Effect of branched-chain amino acid supplementation during unloading on regulatory components of protein synthesis in atrophied soleus muscles.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0038910

Branched-chain amino acids protect against dexamethasone-induced soleus muscle atrophy in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0038910

The COX-2 pathway regulates growth of atrophied muscle via multiple mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0038910

Targeted expression of IGF-1 transgene to skeletal muscle accelerates muscle and motor neuron regeneration.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382153

TNF-alpha impairs heart and skeletal muscle protein synthesis by altering translation initiation

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382153

Hormone, cytokine, and nutritional regulation of sepsis-induced increases in atrogin-1 and MuRF1 in skeletal muscle

28 October 2018

1 reference

12 December 2020

The deleterious effects of bed rest on human skeletal muscle fibers are exacerbated by hypercortisolemia and ameliorated by dietary supplementation

1 reference

12 December 2020

Class 2 IGF-1 isoforms are dispensable for viability, growth and maintenance of IGF-1 serum levels

1 reference

12 December 2020

POINT: IGF IS THE MAJOR PHYSIOLOGICAL REGULATOR OF MUSCLE MASS

1 reference

12 December 2020

Point:Counterpoint: IGF is/is not the major physiological regulator of muscle mass. Counterpoint: IGF is not the major physiological regulator of muscle mass

1 reference

12 December 2020

Lack of muscle recovery after immobilization in old rats does not result from a defect in normalization of the ubiquitin-proteasome and the caspase-dependent apoptotic pathways

1 reference

12 December 2020

Acute antibody-directed myostatin inhibition attenuates disuse muscle atrophy and weakness in mice

1 reference

12 December 2020

Insulin-like growth factor-I gene transfer by electroporation prevents skeletal muscle atrophy in glucocorticoid-treated rats

1 reference

12 December 2020

Changes in PKB/Akt and calcineurin signaling during recovery in atrophied soleus muscle induced by unloading

1 reference

12 December 2020

Temporal alterations in protein signaling cascades during recovery from muscle atrophy

1 reference

12 December 2020

Responsiveness of cell signaling pathways during the failed 15-day regrowth of aged skeletal muscle

1 reference

12 December 2020

Protein synthesis rates in atrophied gastrocnemius muscles after limb immobilization

1 reference

12 December 2020

Decrease in human quadriceps muscle protein turnover consequent upon leg immobilization

1 reference

12 December 2020

Overexpression of IGF-I in skeletal muscle of transgenic mice does not prevent unloading-induced atrophy

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0038910

Identifiers

DOI

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1 August 2017

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1 August 2017

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