(Q34321354)

1 August 2017

title

Dual mechanisms of HNO generation by a nitroxyl prodrug of the diazeniumdiolate (NONOate) class (English)

1 reference

1 August 2017

Daniela Andrei

1

1 reference

1 August 2017

Debra J Salmon

2

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1 August 2017

Sonia Donzelli

3

1 reference

1 August 2017

Azadeh Wahab

4

1 reference

1 August 2017

John R Klose

5

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1 August 2017

Michael L Citro

6

1 reference

1 August 2017

Joseph E Saavedra

7

1 reference

1 August 2017

David A Wink

8

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1 August 2017

Katrina M Miranda

9

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1 August 2017

Larry K Keefer

10

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1 August 2017

language of work or name

English

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publication date

29 October 2010

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Journal of the American Chemical Society

1 August 2017

published in

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1 August 2017

volume

132

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1 August 2017

issue

46

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1 August 2017

page(s)

16526-16532

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Nitroxyl activates SERCA in cardiac myocytes via glutathiolation of cysteine 674.

1 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984372

Examining nitroxyl in biological systems

6 July 2018

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The pharmacology of nitroxyl (HNO) and its therapeutic potential: not just the Janus face of NO

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984372

Hydrolysis of Acyloxy Nitroso Compounds Yields Nitroxyl (HNO)

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984372

Mechanism of pH-dependent decomposition of monoalkylamine diazeniumdiolates to form HNO and NO, deduced from the model compound methylamine diazeniumdiolate, density functional theory, and CBS-QB3 calculations

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984372

Comparison of the NO and HNO donating properties of diazeniumdiolates: primary amine adducts release HNO in Vivo

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984372

N-hydroxyurea and acyl nitroso compounds as nitroxyl (HNO) and nitric oxide (NO) donors

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984372

6 July 2018

1 reference

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Mechanisms of reductive nitrosylation in iron and copper models relevant to biological systems

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984372

A biochemical rationale for the discrete behavior of nitroxyl and nitric oxide in the cardiovascular system

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984372

Orthogonal properties of the redox siblings nitroxyl and nitric oxide in the cardiovascular system: a novel redox paradigm.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984372

Positive inotropic and lusitropic effects of HNO/NO − in failing hearts: Independence from β-adrenergic signaling

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984372

Nitroxyl gets to the heart of the matter.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984372

Direct observation of an acyl nitroso species in solution by time-resolved IR spectrocopy

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984372

Nitroxyl and its anion in aqueous solutions: spin states, protic equilibria, and reactivities toward oxygen and nitric oxide

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984372

Mechanistic studies on the reversible binding of nitric oxide to metmyoglobin

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984372

P-Nitrosophosphate compounds: new N-O heterodienophiles and nitroxyl delivery agents

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984372

N,O-diacylated-N-hydroxyarylsulfonamides: nitroxyl precursors with potent smooth muscle relaxant properties

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984372

Oxidative heme protein-mediated nitroxyl (HNO) generation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984372

New insights into the S-nitrosothiol-ascorbate reaction. The formation of nitroxyl.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984372

Modification of tubulin cysteines by nitric oxide and nitroxyl donors alters tubulin polymerization activity

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984372

Effect of nitroxyl on the hamster retinal nitridergic pathway.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984372

Antioxidant actions of nitroxyl (HNO).

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984372

N-Hydroxy sulfonimidamides as new nitroxyl (HNO) donors

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984372

Nitroxyl triggers Ca2+ release from skeletal and cardiac sarcoplasmic reticulum by oxidizing ryanodine receptors

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984372

Nitroxyl (HNO) release from new functionalized N-hydroxyurea-derived acyl nitroso-9,10-dimethylanthracene cycloadducts

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984372

Chemistry of the diazeniumdiolates. O- versus N-alkylation of the RNH[N(O)NO](-) ion.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984372

Catalase-mediated nitric oxide formation from hydroxyurea

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984372

Reaction mechanism between nitric oxide and glutathione mediated by Fe(III) myoglobin

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984372

N-hydroxybenzenecarboximidic acid derivatives: a new class of nitroxyl-generating prodrugs

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984372

Prodrugs of nitroxyl as inhibitors of aldehyde dehydrogenase

28 October 2018

1 reference

12 December 2020

Chemistry of the diazeniumdiolates: Z right harpoon over left harpoon E isomerism

1 reference

12 December 2020

Mechanisms and novel directions in the biological applications of nitric oxide donors

1 reference

12 December 2020

Prodrugs of Nitroxyl as Potential Aldehyde Dehydrogenase Inhibitors vis-a-vis Vascular Smooth Muscle Relaxants

1 reference

12 December 2020

The nitroxyl anion (HNO) is a potent dilator of rat coronary vasculature

1 reference

12 December 2020

Nitroxyl analogs as inhibitors of aldehyde dehydrogenase. C-nitroso compounds

1 reference

12 December 2020

Nitroxyl anion donor, Angeli's salt, does not develop tolerance in rat isolated aortae

1 reference

12 December 2020

Complexes of .NO with nucleophiles as agents for the controlled biological release of nitric oxide. Vasorelaxant effects

1 reference

12 December 2020

Identifiers

DOI

10.1021/JA106552P

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1 August 2017

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1 August 2017

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