(Q34325319)

1 August 2017

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title

Genetics of morphogen gradients (English)

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1 August 2017

Tabata T

1

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1 August 2017

1 August 2001

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1 August 2017

Nature Reviews Genetics

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1 August 2017

2

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1 August 2017

620-630

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1 August 2017

8

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https://scigraph.springernature.com/pub.10.1038/35084577

1 August 2017

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Genetic ablation reveals that the roof plate is essential for dorsal interneuron specification

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Sticking together and sorting things out: adhesion as a force in development

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Distinguishable functions for engrailed and invected in anterior-posterior patterning in the Drosophila wing.

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Hedgehog is a signaling protein with a key role in patterning Drosophila imaginal discs

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Compartment boundaries and the control of Drosophila limb pattern by hedgehog protein

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Two distinct mechanisms for long-range patterning by Decapentaplegic in the Drosophila wing.

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Direct and long-range action of a DPP morphogen gradient.

21 January 2018

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fringe, a Boundary-specific signaling molecule, mediates interactions between dorsal and ventral cells during Drosophila wing development.

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Interaction between dorsal and ventral cells in the imaginal disc directs wing development in Drosophila.

21 January 2018

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Cell recognition, signal induction, and symmetrical gene activation at the dorsal-ventral boundary of the developing Drosophila wing.

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Delta is a ventral to dorsal signal complementary to Serrate, another Notch ligand, in Drosophila wing formation

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Direct and long-range action of a wingless morphogen gradient.

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How cells read TGF-beta signals

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Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function

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A hedgehog-insensitive form of patched provides evidence for direct long-range morphogen activity of sonic hedgehog in the neural tube.

21 January 2018

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Cholesterol modification of sonic hedgehog is required for long-range signaling activity and effective modulation of signaling by Ptc1

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The zebrafish Nodal signal Squint functions as a morphogen

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Dpp gradient formation in the Drosophila wing imaginal disc.

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Gradient formation of the TGF-beta homolog Dpp.

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Requirement for dynamin during Notch signaling in Drosophila neurogenesis.

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Control of EGF receptor signaling by clathrin-mediated endocytosis.

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The range of spalt-activating Dpp signalling is reduced in endocytosis-defective Drosophila wing discs.

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Transducing Hedgehog: the story so far

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Hedgehog induces opposite changes in turnover and subcellular localization of patched and smoothened

21 January 2018

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Posttranscriptional regulation of smoothened is part of a self-correcting mechanism in the Hedgehog signaling system

21 January 2018

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The sterol-sensing domain of Patched protein seems to control Smoothened activity through Patched vesicular trafficking

21 January 2018

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Proteoglycans: structures and interactions

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The cell-surface proteoglycan Dally regulates Wingless signalling in Drosophila

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Dally cooperates with Drosophila Frizzled 2 to transduce Wingless signalling.

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The product of hedgehog autoproteolytic cleavage active in local and long-range signalling.

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Cholesterol modification of hedgehog signaling proteins in animal development

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Dispatched, a novel sterol-sensing domain protein dedicated to the release of cholesterol-modified hedgehog from signaling cells

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Hedgehog movement is regulated through tout velu-dependent synthesis of a heparan sulfate proteoglycan.

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The EXT1/EXT2 tumor suppressors: catalytic activities and role in heparan sulfate biosynthesis

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Cloning of the putative tumour suppressor gene for hereditary multiple exostoses (EXT1)

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The EXT2 multiple exostoses gene defines a family of putative tumour suppressor genes

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Regulation of rate of cartilage differentiation by Indian hedgehog and PTH-related protein

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Indian hedgehog signaling regulates proliferation and differentiation of chondrocytes and is essential for bone formation

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Hedgehog creates a gradient of DPP activity in Drosophila wing imaginal discs.

21 January 2018

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Daughters against dpp modulates dpp organizing activity in Drosophila wing development.

21 January 2018

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Dual roles for patched in sequestering and transducing Hedgehog

21 January 2018

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A new member of the frizzled family from Drosophila functions as a Wingless receptor

21 January 2018

1 reference

Wingless repression of Drosophila frizzled 2 expression shapes the Wingless morphogen gradient in the wing

21 January 2018

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Regulation of patched by sonic hedgehog in the developing neural tube

21 January 2018

1 reference

Transducing the Dpp morphogen gradient in the wing of Drosophila: regulation of Dpp targets by brinker

21 January 2018

1 reference

The Drosophila gene brinker reveals a novel mechanism of Dpp target gene regulation.

21 January 2018

1 reference

brinker is a target of Dpp in Drosophila that negatively regulates Dpp-dependent genes.

21 January 2018

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Direct transcriptional control of the Dpp target omb by the DNA binding protein Brinker

21 January 2018

1 reference

Transcriptional regulation of the Drosophila gene zen by competing Smad and Brinker inputs

21 January 2018

1 reference

Repression of dpp targets by binding of brinker to mad sites.

21 January 2018

1 reference

Proteolysis that is inhibited by hedgehog targets Cubitus interruptus protein to the nucleus and converts it to a repressor

21 January 2018

1 reference

Hedgehog controls limb development by regulating the activities of distinct transcriptional activator and repressor forms of Cubitus interruptus.

21 January 2018

1 reference

Nuclear trafficking of Cubitus interruptus in the transcriptional regulation of Hedgehog target gene expression

21 January 2018

1 reference

pangolin encodes a Lef-1 homologue that acts downstream of Armadillo to transduce the Wingless signal in Drosophila.

21 January 2018

1 reference

Armadillo coactivates transcription driven by the product of the Drosophila segment polarity gene dTCF

21 January 2018

1 reference

Drosophila Tcf and Groucho interact to repress Wingless signalling activity.

21 January 2018

1 reference

Mouse suppressor of fused is a negative regulator of sonic hedgehog signaling and alters the subcellular distribution of Gli1

21 January 2018

1 reference

Hedgehog-regulated processing of Gli3 produces an anterior/posterior repressor gradient in the developing vertebrate limb

21 January 2018

1 reference

Curbing the nuclear activities of beta-catenin. Control over Wnt target gene expression

21 January 2018

1 reference

The Xenopus Wnt effector XTcf-3 interacts with Groucho-related transcriptional repressors

21 January 2018

1 reference

A conserved system for dorsal-ventral patterning in insects and vertebrates involving sog and chordin.

21 January 2018

1 reference

Cytonemes: cellular processes that project to the principal signaling center in Drosophila imaginal discs

21 January 2018

1 reference

The FLP recombinase of yeast catalyzes site-specific recombination in the Drosophila genome.

21 January 2018

1 reference

Region-specific recombination and expression are directed by portions of the Drosophila engrailed promoter.

21 January 2018

1 reference

Wingless gradient formation in the Drosophila wing

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1038/35084577

1 reference

PubMed ID

11483986

Dimensions Publication ID

1 August 2017

0 references

1 reference

PubMed ID

11483986