(Q34325628)

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Computational predictions of volatile anesthetic interactions with the microtubule cytoskeleton: implications for side effects of general anesthesia

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7 February 2020

Computational predictions of volatile anesthetic interactions with the microtubule cytoskeleton: implications for side effects of general anesthesia (English)

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7 February 2020

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general anaesthesia

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based on heuristic

inferred from title

volatile anaesthetic

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based on heuristic

inferred from title

4

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7 February 2020

Jack Tuszyński

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7 February 2020

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Travis J A Craddock

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7 February 2020

Marc St George

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7 February 2020

Holly Freedman

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7 February 2020

Sambasivarao Damaraju

5

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7 February 2020

Stuart Hameroff

6

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7 February 2020

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25 June 2012

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7 February 2020

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7 February 2020

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7 February 2020

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7 February 2020

e37251

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7 February 2020

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Creative Commons Attribution 4.0 International

25 June 2012

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April 2022 Public Data File from Crossref

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0 references

The zinc dyshomeostasis hypothesis of Alzheimer's disease

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Cytoskeletal signaling: is memory encoded in microtubule lattices by CaMKII phosphorylation?

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Review of clinical evidence for persistent cognitive decline or incident dementia attributable to surgery or general anesthesia

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6 July 2018

"Memory bytes" - molecular match for CaMKII phosphorylation encoding of microtubule lattices

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6 July 2018

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6 July 2018

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6 July 2018

Drugs of anaesthesia and cancer

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6 July 2018

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6 July 2018

Roles of beta-tubulin residues Ala428 and Thr429 in microtubule formation in vivo

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6 July 2018

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6 July 2018

A unique mode of microtubule stabilization induced by peloruside A

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6 July 2018

Prediction of volatile anesthetic binding sites in proteins.

1 reference

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6 July 2018

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6 July 2018

Scalable molecular dynamics with NAMD

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6 July 2018

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6 July 2018

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6 July 2018

Inhalational anesthetic-binding proteins in rat neuronal membranes

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6 July 2018

Alteration in calcium channel properties is responsible for the neurotoxic action of a familial frontotemporal dementia tau mutation

1 reference

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6 July 2018

Mechanisms of actions of inhaled anesthetics

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6 July 2018

Repeat motifs of tau bind to the insides of microtubules in the absence of taxol

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6 July 2018

Efficient docking of peptides to proteins without prior knowledge of the binding site

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6 July 2018

Refined structure of alpha beta-tubulin at 3.5 A resolution

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6 July 2018

Vinca alkaloid-induced tubulin spiral formation correlates with cytotoxicity in the leukemic L1210 cell line

1 reference

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6 July 2018

Volatile anesthetics block actin-based motility in dendritic spines

1 reference

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6 July 2018

GABA(A)-receptor-associated protein links GABA(A) receptors and the cytoskeleton

1 reference

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6 July 2018

Structure of the alpha beta tubulin dimer by electron crystallography

1 reference

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6 July 2018

Sites of alcohol and volatile anaesthetic action on GABA(A) and glycine receptors.

1 reference

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6 July 2018

Cation selective promotion of tubulin polymerization by alkali metal chlorides

1 reference

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6 July 2018

Activation of endogenous protein kinase C by halothane in synaptosomes

1 reference

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6 July 2018

Central nervous system sodium channels are significantly suppressed at clinical concentrations of volatile anesthetics.

1 reference

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6 July 2018

Muscarinic signaling in the central nervous system. Recent developments and anesthetic implications

1 reference

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6 July 2018

Inhibition of dopamine transport in rat brain synaptosomes by volatile anesthetics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382613

6 July 2018

Inhibition of protein kinase C by alcohols and anaesthetics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382613

6 July 2018

Comparative protein modelling by satisfaction of spatial restraints

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382613

6 July 2018

Taxol: the chemistry and structure-activity relationships of a novel anticancer agent

1 reference

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6 July 2018

Anesthetics alter the physical and functional properties of the Ca-ATPase in cardiac sarcoplasmic reticulum

1 reference

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6 July 2018

Ca2+ channel Ca(2+)-dependent inactivation in a mammalian central neuron involves the cytoskeleton

1 reference

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6 July 2018

Molecular and cellular mechanisms of general anaesthesia

1 reference

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6 July 2018

Halothane Modifies Colchicine Binding to Tubulin

1 reference

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6 July 2018

Do general anaesthetics act by competitive binding to specific receptors?

1 reference

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6 July 2018

Involvement of the carboxyl-terminal domain of tubulin in the regulation of its assembly

1 reference

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6 July 2018

The Effect of Inhalational Anaesthetics on the Microtubular System in Actinosphaerium Nucleofilum

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6 July 2018

Effects of halothane and colchicine on microtubules and electrical activity of rabbit vagus nerves

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6 July 2018

Anesthetic-induced transformation of axonal microtubules

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6 July 2018

Effects of general anaesthetics on microtubules: a possible mechanism of anaesthesia

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6 July 2018

Tubulin subunit carboxyl termini determine polymerization efficiency.

1 reference

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6 July 2018

Tubulin, hybrid dimers, and tubulin S. Stepwise charge reduction and polymerization.

1 reference

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6 July 2018

Phosphorylation of tubulin by a calmodulin-dependent protein kinase

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6 July 2018

Microtubule-associated protein MAP2 shares a microtubule binding motif with tau protein

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6 July 2018

Effect of specific proteolytic cleavages on tubulin polymer formation

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6 July 2018

Dexmedetomidine diminishes halothane anesthetic requirements in rats through a postsynaptic alpha 2 adrenergic receptor

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6 July 2018

Disruption of muscarinic receptor-G protein coupling is a general property of liquid volatile anesthetics.

1 reference

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6 July 2018

A model for microtubule-associated protein 4 structure. Domains defined by comparisons of human, mouse, and bovine sequences

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6 July 2018

The conversion of tubulin carboxyl groups to amides has a stabilizing effect on microtubules

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6 July 2018

Anaesthetics depress the sensitivity of cortical neurones to L-glutamate

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6 July 2018

The inhibition of flagellar regeneration in Chlamydomonas reinhardii by inhalational anesthetic halothane

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6 July 2018

Macrotubules induced by halothane: in vitro assembly.

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6 July 2018

Effects of halothane on microtubules in the sciatic nerve of the rat

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6 July 2018

Effect of halothane on microtubule numbers in unmyelinated axons from rat sciatic nerve [proceedings]

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6 July 2018

Microtubule—macrotubule transformations induced by volatile anesthetics. Mechanism of macrotubule assembly

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6 July 2018

Halogenated general anesthetics in visual photoreceptor membranes as examined by static and dynamic properties of rhodopsin.

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21 January 2018

Alcohols inhibit a cloned potassium channel at a discrete saturable site. Insights into the molecular basis of general anesthesia.

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21 January 2018

Anesthetic and nonanesthetic halogenated volatile compounds have dissimilar activities on nicotinic acetylcholine receptor desensitization kinetics.

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21 January 2018

Sites of volatile anesthetic action on kainate (Glutamate receptor 6) receptors.

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21 January 2018

Multiple specific binding targets for inhaled anesthetics in the mammalian brain

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21 January 2018

Halothane binding proteome in human brain cortex

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21 January 2018

Cytoskeleton mediates inhibition of the fast Na+ current in respiratory brainstem neurons during hypoxia

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21 January 2018

A cytoskeletal mechanism for Ca2+ channel metabolic dependence and inactivation by intracellular Ca2+.

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21 January 2018

Anesthesia-Alzheimer disease link probed.

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21 January 2018

Alterations in rat brain proteins after desflurane anesthesia

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21 January 2018

The effects of sevoflurane anesthesia on rat brain proteins: a proteomic time-course analysis

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21 January 2018

Inhaled anesthetics elicit region-specific changes in protein expression in mammalian brain

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21 January 2018

Tau phosphorylation and sevoflurane anesthesia: an association to postoperative cognitive impairment.

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21 January 2018

Postoperative cognitive decline: where art tau?

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21 January 2018

A guest molecule-host cavity fitting algorithm to mine PDB for small molecule targets.

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21 January 2018

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21 January 2018

Insight into tubulin regulation from a complex with colchicine and a stathmin-like domain.

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21 January 2018

Structural basis for the regulation of tubulin by vinblastine

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21 January 2018

Different effects of vinblastine on the polymerization of isotypically purified tubulins from bovine brain

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21 January 2018

Microtubule-macrotubule transitions: intermediates after exposure to the mitotic inhibitor vinblastine.

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21 January 2018

Volatile anesthetics modulate the binding of guanine nucleotides to the alpha subunits of heterotrimeric GTP binding proteins.

1 reference

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21 January 2018

Prediction of zinc-binding sites in proteins from sequence.

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21 January 2018

Conduction pathways in microtubules, biological quantum computation, and consciousness.

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21 January 2018

Photolabeling of Prostaglandin Endoperoxide H Synthase-1 with 3-Trifluoro-3-(m-Iiodophenyl)diazirine as a Probe of Membrane Association and the Cyclooxygenase Active Site

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21 January 2018

Homology modeling of tubulin: influence predictions for microtubule's biophysical properties.

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21 January 2018

Comparative modelling of human β tubulin isotypes and implications for drug binding.

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21 January 2018

GROMACS: A message-passing parallel molecular dynamics implementation

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21 January 2018

Numerical integration of the cartesian equations of motion of a system with constraints: molecular dynamics of n-alkanes

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21 January 2018

The Tubulin Binding Mode of MT Stabilizing and Destabilizing Agents Studied by NMR.

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28 October 2018

Anesthetics and Alzheimer's disease: background and research. Preface

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28 October 2018

Quantitative autoradiography of halothane binding in rat brain.

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28 October 2018

Mechanism of action cryptophycin. Interaction with the Vinca alkaloid domain of tubulin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382613

28 October 2018

GROMACS 3.0: a package for molecular simulation and trajectory analysis

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0037251

21 January 2018

Microtubule structure at 8 A resolution

1 reference

https://pubmed.ncbi.nlm.nih.gov/22761654

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of somatodendritic GABAA receptor channels in rat hippocampal neurons: evidence for a role of the small GTPase Rac1

1 reference

https://pubmed.ncbi.nlm.nih.gov/22761654

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular dynamics modeling of tubulin C-terminal tail interactions with the microtubule surface

1 reference

https://pubmed.ncbi.nlm.nih.gov/22761654

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vinblastine-induced paracrystals and unusually large microtubules (macrotubules) in rat renal cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22761654

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Zinc ion-induced assembly of tubulin

1 reference

https://pubmed.ncbi.nlm.nih.gov/22761654

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Taxol stabilizes [Ca2+]i and protects hippocampal neurons against excitotoxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/22761654

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutations of tau protein in frontotemporal dementia promote aggregation of paired helical filaments by enhancing local beta-structure

1 reference

https://pubmed.ncbi.nlm.nih.gov/22761654

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of the interaction of cryptophycin 1 with tubulin: binding in the Vinca domain, competitive inhibition of dolastatin 10 binding, and an unusual aggregation reaction

1 reference

https://pubmed.ncbi.nlm.nih.gov/22761654

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0037251

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22761654%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

2012PLoSO...737251C

0 references

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22761654%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22761654%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

ResearchGate publication ID

0 references

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