(Q34328588)

1 August 2017

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title

VEGF-VEGF receptor complexes as markers of tumor vascular endothelium (English)

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1 August 2017

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Brekken RA

1

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1 August 2017

Thorpe PE

series ordinal

2

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1 August 2017

language of work or name

English

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publication date

1 July 2001

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Journal of Controlled Release

1 August 2017

published in

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1 August 2017

volume

74

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1 August 2017

issue

1-3

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1 August 2017

page(s)

173-181

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Transport of fluid and macromolecules in tumors. III. Role of binding and metabolism

1 August 2017

cites work

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Distribution of vascular permeability factor (vascular endothelial growth factor) in tumors: concentration in tumor blood vessels

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VEGFs, receptors and angiogenesis

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Vascular endothelial growth factor (VEGF) and its receptors

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Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor

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VEGF receptor signaling in tumor angiogenesis

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Flt-1 lacking the tyrosine kinase domain is sufficient for normal development and angiogenesis in mice

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Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium

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Receptor chimeras indicate that the vascular endothelial growth factor receptor-1 (VEGFR-1) modulates mitogenic activity of VEGFR-2 in endothelial cells

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The pivotal role of VEGF in tumor angiogenesis: molecular facts and therapeutic opportunities

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Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo

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An anti-human VEGF monoclonal antibody, MV833, that exhibits potent anti-tumor activity in vivo

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Role of vascular endothelial growth factor in ovarian cancer: inhibition of ascites formation by immunoneutralization

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Impact of oncogenes in tumor angiogenesis: mutant K-ras up-regulation of vascular endothelial growth factor/vascular permeability factor is necessary, but not sufficient for tumorigenicity of human colorectal carcinoma cells

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Identification of vascular endothelial growth factor determinants for binding KDR and FLT-1 receptors. Generation of receptor-selective VEGF variants by site-directed mutagenesis

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VEGF and the Fab fragment of a humanized neutralizing antibody: crystal structure of the complex at 2.4 A resolution and mutational analysis of the interface

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7 January 2021

Crystal structure at 1.7 A resolution of VEGF in complex with domain 2 of the Flt-1 receptor

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7 January 2021

Ultrastructural localization of the vascular permeability factor/vascular endothelial growth factor (VPF/VEGF) receptor-2 (FLK-1, KDR) in normal mouse kidney and in the hyperpermeable vessels induced by VPF/VEGF-expressing tumors and adenoviral vect

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Time-dependent vascular regression and permeability changes in established human tumor xenografts induced by an anti-vascular endothelial growth factor/vascular permeability factor antibody

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Ultrastructural localization of vascular permeability factor/vascular endothelial growth factor (VPF/VEGF) to the abluminal plasma membrane and vesiculovacuolar organelles of tumor microvascular endothelium

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7 January 2021

Neutralizing anti-vascular endothelial growth factor antibody completely inhibits angiogenesis and growth of human prostate carcinoma micro tumors in vivo

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Selective ablation of immature blood vessels in established human tumors follows vascular endothelial growth factor withdrawal

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7 January 2021

Formation of endothelial cell networks

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7 January 2021

The Vascular Endothelial Growth Factor Receptor Flt-1 Mediates Biological Activities

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VEGF couples hypertrophic cartilage remodeling, ossification and angiogenesis during endochondral bone formation

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Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis

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Continuous low-dose therapy with vinblastine and VEGF receptor-2 antibody induces sustained tumor regression without overt toxicity

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Identifiers

DOI

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1 August 2017

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