(Q34331434)

1 August 2017

title

Mechanistic links between COPD and lung cancer (English)

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chronic obstructive pulmonary disease

1 August 2017

main subject

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A McGarry Houghton

1

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1 August 2017

language of work or name

English

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publication date

7 March 2013

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1 August 2017

published in

Nature Reviews Cancer

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1 August 2017

volume

13

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1 August 2017

issue

4

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1 August 2017

page(s)

233-245

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Tobacco--the growing epidemic

1 August 2017

cites work

1 reference

The International Epidemiology of Lung Cancer: geographical distribution and secular trends.

31 March 2020

1 reference

Relationship between reduced forced expiratory volume in one second and the risk of lung cancer: a systematic review and meta-analysis

31 March 2020

1 reference

Higher risk of lung cancer in chronic obstructive pulmonary disease. A prospective, matched, controlled study

31 March 2020

1 reference

Airways obstruction and the risk for lung cancer

31 March 2020

1 reference

Ventilatory function and chronic mucus hypersecretion as predictors of death from lung cancer

31 March 2020

1 reference

Chronic obstructive pulmonary disease mortality in six U.S. cities

31 March 2020

1 reference

Mortality in COPD: Role of comorbidities.

31 March 2020

1 reference

COPD prevalence is increased in lung cancer, independent of age, sex and smoking history

31 March 2020

1 reference

Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease. NHLBI/WHO Global Initiative for Chronic Obstructive Lung Disease (GOLD) Workshop summary

31 March 2020

1 reference

The pathogenesis of chronic obstructive pulmonary disease: advances in the past 100 years

31 March 2020

1 reference

Epidemiology and global impact of chronic obstructive pulmonary disease

31 March 2020

1 reference

31 March 2020

Global cancer statistics

1 reference

International Association for the Study of Lung Cancer/American Thoracic Society/European Respiratory Society: international multidisciplinary classification of lung adenocarcinoma: executive summary.

31 March 2020

1 reference

Lung cancer in never smokers--a different disease

31 March 2020

1 reference

Lung cancer and chronic obstructive pulmonary disease: needs and opportunities for integrated research

31 March 2020

1 reference

Association of radiographic emphysema and airflow obstruction with lung cancer

31 March 2020

1 reference

Computed tomography-diagnosed emphysema, not airway obstruction, is associated with the prognostic outcome of early-stage lung cancer.

31 March 2020

1 reference

Assessing the relationship between lung cancer risk and emphysema detected on low-dose CT of the chest.

31 March 2020

1 reference

Effect of emphysema on lung cancer risk in smokers: a computed tomography-based assessment

31 March 2020

1 reference

Emphysema scores predict death from COPD and lung cancer.

31 March 2020

1 reference

Quantitative computed tomography analysis, airflow obstruction, and lung cancer in the pittsburgh lung screening study

31 March 2020

1 reference

Are airflow obstruction and radiographic evidence of emphysema risk factors for lung cancer? A nested case-control study using quantitative emphysema analysis

31 March 2020

1 reference

Molecular pathogenesis of emphysema

31 March 2020

1 reference

Chronic obstructive pulmonary disease

31 March 2020

1 reference

31 March 2020

1 reference

Molecular basis of alpha-1-antitrypsin deficiency

31 March 2020

1 reference

Marked longevity of human lung parenchymal elastic fibers deduced from prevalence of D-aspartate and nuclear weapons-related radiocarbon

31 March 2020

1 reference

EXPERIMENTAL EMPHYSEMA: ITS PRODUCTION WITH PAPAIN IN NORMAL AND SILICOTIC RATS

31 March 2020

1 reference

Alpha1-antitrypsin deficiency carriers, tobacco smoke, chronic obstructive pulmonary disease, and lung cancer risk

31 March 2020

1 reference

Alpha1-antitrypsin and neutrophil elastase imbalance and lung cancer risk

31 March 2020

1 reference

A novel antiapoptotic role for alpha1-antitrypsin in the prevention of pulmonary emphysema

31 March 2020

1 reference

The SERPINE2 gene is associated with chronic obstructive pulmonary disease

31 March 2020

1 reference

Variants in FAM13A are associated with chronic obstructive pulmonary disease

31 March 2020

1 reference

Loci identified by genome-wide association studies influence different disease-related phenotypes in chronic obstructive pulmonary disease

31 March 2020

1 reference

A variant associated with nicotine dependence, lung cancer and peripheral arterial disease

31 March 2020

1 reference

A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25

31 March 2020

1 reference

Genome-wide association scan of tag SNPs identifies a susceptibility locus for lung cancer at 15q25.1

31 March 2020

1 reference

Silencing of genes by promoter hypermethylation: key event in rodent and human lung cancer

31 March 2020

1 reference

Defective expression of transforming growth factor beta receptor type II is associated with CpG methylated promoter in primary non-small cell lung cancer

31 March 2020

1 reference

The CpG island of the novel tumor suppressor gene RASSF1A is intensely methylated in primary small cell lung carcinomas

31 March 2020

1 reference

Aberrant methylation of p16(INK4a) is an early event in lung cancer and a potential biomarker for early diagnosis

31 March 2020

1 reference

Variable DNA methylation is associated with chronic obstructive pulmonary disease and lung function

31 March 2020

1 reference

Inhibition of VEGF receptors causes lung cell apoptosis and emphysema

31 March 2020

1 reference

Alveolar wall apoptosis causes lung destruction and emphysematous changes

31 March 2020

1 reference

Vascular atrophy and VEGFR-2 signaling: old theories of pulmonary emphysema meet new data

31 March 2020

1 reference

Hallmarks of Cancer: The Next Generation

31 March 2020

1 reference

The field of tissue injury in the lung and airway

31 March 2020

1 reference

Field cancerization in oral stratified squamous epithelium; clinical implications of multicentric origin

31 March 2020

1 reference

Widely dispersed p53 mutation in respiratory epithelium. A novel mechanism for field carcinogenesis

31 March 2020

1 reference

Clonality and prognostic implications of p53 and epidermal growth factor receptor somatic aberrations in multiple primary lung cancers.

31 March 2020

1 reference

Molecular damage in the bronchial epithelium of current and former smokers

31 March 2020

1 reference

EGFR tyrosine kinase domain mutations are detected in histologically normal respiratory epithelium in lung cancer patients

31 March 2020

1 reference

K-ras activation generates an inflammatory response in lung tumors

31 March 2020

1 reference

Ras-induced interleukin-8 expression plays a critical role in tumor growth and angiogenesis

31 March 2020

1 reference

Airway epithelial gene expression in the diagnostic evaluation of smokers with suspect lung cancer

31 March 2020

1 reference

Airway PI3K pathway activation is an early and reversible event in lung cancer development

31 March 2020

1 reference

Analysis of lung tumor initiation and progression using conditional expression of oncogenic K-ras

31 March 2020

1 reference

Identification of bronchioalveolar stem cells in normal lung and lung cancer

31 March 2020

1 reference

Do all lung adenocarcinomas follow a stepwise progression?

31 March 2020

1 reference

Cell recovery in bronchoalveolar lavage fluid in smokers is dependent on cumulative smoking history

31 March 2020

1 reference

Bronchoalveolar lavage cellularity. The distribution in normal volunteers

31 March 2020

1 reference

The nature of small-airway obstruction in chronic obstructive pulmonary disease

31 March 2020

1 reference

31 March 2020

Inflammation and cancer

1 reference

An immune basis for lung parenchymal destruction in chronic obstructive pulmonary disease and emphysema

31 March 2020

1 reference

Smoking-dependent reprogramming of alveolar macrophage polarization: implication for pathogenesis of chronic obstructive pulmonary disease

31 March 2020

1 reference

Smoking status and anti-inflammatory macrophages in bronchoalveolar lavage and induced sputum in COPD.

31 March 2020

1 reference

CD8+ T Cells are required for inflammation and destruction in cigarette smoke-induced emphysema in mice.

31 March 2020

1 reference

Cigarette smoke induces interleukin-8 release from human bronchial epithelial cells

31 March 2020

1 reference

Lung myeloid dendritic cells coordinately induce TH1 and TH17 responses in human emphysema.

31 March 2020

1 reference

IL-17RA is required for CCL2 expression, macrophage recruitment, and emphysema in response to cigarette smoke

31 March 2020

1 reference

Paradoxical roles of the immune system during cancer development

31 March 2020

1 reference

Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes

31 March 2020

1 reference

Myeloid-derived suppressor cells as regulators of the immune system

31 March 2020

1 reference

Polarization of tumor-associated neutrophil phenotype by TGF-beta: "N1" versus "N2" TAN

31 March 2020

1 reference

Promotion of lung carcinogenesis by chronic obstructive pulmonary disease-like airway inflammation in a K-ras-induced mouse model

31 March 2020

1 reference

Tumors induce a subset of inflammatory monocytes with immunosuppressive activity on CD8+ T cells

31 March 2020

1 reference

Regulatory T cells suppress tumor-specific CD8 T cell cytotoxicity through TGF-beta signals in vivo

31 March 2020

1 reference

Immune suppression in cancer: effects on immune cells, mechanisms and future therapeutic intervention

31 March 2020

1 reference

IL-17 can promote tumor growth through an IL-6-Stat3 signaling pathway

31 March 2020

1 reference

T helper 17 cells promote cytotoxic T cell activation in tumor immunity

31 March 2020

1 reference

Expression of interleukin-8 promotes neutrophil infiltration and genetic instability in mutatect tumors

31 March 2020

1 reference

The paradox of pro-inflammatory cytokines in cancer

31 March 2020

1 reference

Tobacco smoke promotes lung tumorigenesis by triggering IKKbeta- and JNK1-dependent inflammation

31 March 2020

1 reference

Xenobiotic-metabolizing enzymes in human lung

31 March 2020

1 reference

Metabolism of Polycyclic Aromatic Hydrocarbon Derivatives to Ultimate Carcinogens During Lipid Peroxidation

31 March 2020

1 reference

The Nrf2-antioxidant response element signaling pathway and its activation by oxidative stress

31 March 2020

1 reference

Genetic ablation of Nrf2 enhances susceptibility to cigarette smoke-induced emphysema in mice

31 March 2020

1 reference

Nrf2-deficiency creates a responsive microenvironment for metastasis to the lung.

31 March 2020

1 reference

Modulation of the metabolism of airborne pollutants by glucoraphanin-rich and sulforaphane-rich broccoli sprout beverages in Qidong, China

31 March 2020

1 reference

Curcumin chemoprevention: the long road to clinical translation

31 March 2020

1 reference

Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis

31 March 2020

1 reference

NRF2 and cancer: the good, the bad and the importance of context.

31 March 2020

1 reference

Nrf2 and Keap1 abnormalities in non-small cell lung carcinoma and association with clinicopathologic features

31 March 2020

1 reference

The serpin alpha1-proteinase inhibitor is a critical substrate for gelatinase B/MMP-9 in vivo.

31 March 2020

1 reference

The role of matrix metalloproteinase-9 in cigarette smoke-induced emphysema.

31 March 2020

1 reference

Release and Activity of Matrix Metalloproteinase-9 and Tissue Inhibitor of Metalloproteinase-1 by Alveolar Macrophages from Patients with Chronic Obstructive Pulmonary Disease

31 March 2020

1 reference

Alveolar macrophage-mediated elastolysis: roles of matrix metalloproteinases, cysteine, and serine proteases

31 March 2020

1 reference

Sputum metalloproteinase-9/tissue inhibitor of metalloproteinase-1 ratio correlates with airflow obstruction in asthma and chronic bronchitis

31 March 2020

1 reference

Infiltrating neutrophils mediate the initial angiogenic switch in a mouse model of multistage carcinogenesis

31 March 2020

1 reference

Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis

31 March 2020

1 reference

MMP-9 supplied by bone marrow-derived cells contributes to skin carcinogenesis

31 March 2020

1 reference

Mediators of vascular remodelling co-opted for sequential steps in lung metastasis.

31 March 2020

1 reference

ADAMTS1 and MMP1 proteolytically engage EGF-like ligands in an osteolytic signaling cascade for bone metastasis

31 March 2020

1 reference

Genes that mediate breast cancer metastasis to lung

31 March 2020

1 reference

Collagenase expression in the lungs of transgenic mice causes pulmonary emphysema.

31 March 2020

1 reference

The role of matrix metalloproteinase polymorphisms in the rate of decline in lung function

31 March 2020

1 reference

Requirement for macrophage elastase for cigarette smoke-induced emphysema in mice

31 March 2020

1 reference

MMP12, lung function, and COPD in high-risk populations

31 March 2020

1 reference

Analysis of host- and tumor-derived proteinases using a custom dual species microarray reveals a protective role for stromal matrix metalloproteinase-12 in non-small cell lung cancer

31 March 2020

1 reference

Macrophage elastase (matrix metalloproteinase-12) suppresses growth of lung metastases

31 March 2020

1 reference

Neutrophil elastase contributes to cigarette smoke-induced emphysema in mice

31 March 2020

1 reference

Neutrophil elastase-mediated degradation of IRS-1 accelerates lung tumor growth

31 March 2020

1 reference

Prognostic significance of immunoreactive neutrophil elastase in human breast cancer: long-term follow-up results in 313 patients

31 March 2020

1 reference

Elastin fragments drive disease progression in a murine model of emphysema

31 March 2020

1 reference

Neutrophil elastase cleaves laminin-332 (laminin-5) generating peptides that are chemotactic for neutrophils

31 March 2020

1 reference

A novel peptide CXCR ligand derived from extracellular matrix degradation during airway inflammation

31 March 2020

1 reference

Reduced lung-cancer mortality with low-dose computed tomographic screening

31 March 2020

1 reference

Lung cancer risk prediction: Prostate, Lung, Colorectal And Ovarian Cancer Screening Trial models and validation.

31 March 2020

1 reference

Inhaled corticosteroids and risk of lung cancer among patients with chronic obstructive pulmonary disease

31 March 2020

1 reference

Salmeterol and fluticasone propionate and survival in chronic obstructive pulmonary disease

31 March 2020

1 reference

Specific inhibition of cyclooxygenase 2 restores antitumor reactivity by altering the balance of IL-10 and IL-12 synthesis

31 March 2020

1 reference

The COX-2/PGE2 pathway: key roles in the hallmarks of cancer and adaptation to the tumour microenvironment

31 March 2020

1 reference

Lung cancer chemoprevention with celecoxib in former smokers

31 March 2020

1 reference

Cardiovascular risk associated with celecoxib in a clinical trial for colorectal adenoma prevention

31 March 2020

1 reference

Induction of cytosolic phospholipase A2 by oncogenic Ras in human non-small cell lung cancer

31 March 2020

1 reference

Pulmonary prostacyclin synthase overexpression chemoprevents tobacco smoke lung carcinogenesis in mice

31 March 2020

1 reference

Oral iloprost improves endobronchial dysplasia in former smokers

31 March 2020

1 reference

Continuous or nocturnal oxygen therapy in hypoxemic chronic obstructive lung disease: a clinical trial. Nocturnal Oxygen Therapy Trial Group

31 March 2020

1 reference

Decreased histone deacetylase activity in chronic obstructive pulmonary disease.

31 March 2020

1 reference

Kinase inhibitors and airway inflammation.

31 March 2020

1 reference

Erlotinib in previously treated non-small-cell lung cancer

31 March 2020

1 reference

Identification of the transforming EML4-ALK fusion gene in non-small-cell lung cancer

31 March 2020

1 reference

Safety and efficacy of an inhaled epidermal growth factor receptor inhibitor (BIBW 2948 BS) in chronic obstructive pulmonary disease

31 March 2020

1 reference

Comprehensive genomic characterization of squamous cell lung cancers

31 March 2020

1 reference

Mapping the hallmarks of lung adenocarcinoma with massively parallel sequencing

31 March 2020

1 reference

The carcinogenicity of environmental tobacco smoke

31 March 2020

1 reference

Lung cancer and cryptogenic fibrosing alveolitis. A population-based cohort study

31 March 2020

1 reference

Z and S mutations of the alpha1-antitrypsin gene and the risk of chronic obstructive pulmonary disease.

31 March 2020

1 reference

Genetic polymorphisms of cytochrome p450 and matrix metalloproteinase in chronic obstructive pulmonary disease.

31 March 2020

1 reference

Proteinase 3. A distinct human polymorphonuclear leukocyte proteinase that produces emphysema in hamsters

31 March 2020

1 reference

Role of cathepsin S-dependent epithelial cell apoptosis in IFN-gamma-induced alveolar remodeling and pulmonary emphysema

31 March 2020

1 reference

Cathepsin S Mediates Gastric Cancer Cell Migration and Invasion via a Putative Network of Metastasis-Associated Proteins

31 March 2020

1 reference

Cathepsin L increases invasion and migration of B16 melanoma

31 March 2020

1 reference

Role for cathepsin K in emphysema in smoke-exposed guinea pigs

31 March 2020

1 reference

Localization of matrix metalloproteinase MMP-2 to the surface of invasive cells by interaction with integrin alpha v beta 3.

31 March 2020

1 reference

Rac1b and reactive oxygen species mediate MMP-3-induced EMT and genomic instability

31 March 2020

1 reference

Loss of collagenase-2 confers increased skin tumor susceptibility to male mice.

31 March 2020

1 reference

Matrix metalloproteinase-13 (MMP-13) directly and indirectly promotes tumor angiogenesis

31 March 2020

1 reference

Matrix metalloproteinase-14 mediates a phenotypic shift in the airways to increase mucin production.

31 March 2020

1 reference

A cancer cell metalloprotease triad regulates the basement membrane transmigration program

31 March 2020

1 reference

Genetic polymorphisms of CYP1A1, GSTM1 and GSTT1 genes and lung cancer risk.

31 March 2020

1 reference

12 December 2020

The induction of emphysema with elastase. II. Changes in connective tissue

1 reference

12 December 2020

A single nucleotide polymorphism in the matrix metalloproteinase-1 promoter enhances lung cancer susceptibility

1 reference

12 December 2020

The prognostic value of polymorphonuclear leukocyte elastase in patients with primary breast cancer.

1 reference

12 December 2020

Natural History and Life Expectancy in Severe Alpha1-Antitrypsin Deficiency, Pi Z

1 reference

12 December 2020

Polymorphisms for microsomal epoxide hydrolase and genetic susceptibility to COPD.

1 reference

12 December 2020

Cyclooxygenase-2 overexpression is a marker of poor prognosis in stage I non-small cell lung cancer

1 reference

12 December 2020

Association between lung cancer and microsomal epoxide hydrolase genotypes.

1 reference

12 December 2020

Alpha1-antitrypsin deficiency allele carriers among lung cancer patients

1 reference

12 December 2020

Reduced angiogenesis and tumor progression in gelatinase A-deficient mice

1 reference

12 December 2020

The pathogenesis of emphysema: the elastase:antielastase hypothesis 30 years later.

1 reference

12 December 2020

Point: myeloperoxidase -463G --> a polymorphism and lung cancer risk.

1 reference

12 December 2020

Alpha-1-antitrypsin deficiency: a review; 1963-1975

1 reference

12 December 2020

CpG methylation inactivates the promoter activity of the human retinoblastoma tumor-suppressor gene.

1 reference

12 December 2020

Matrix metalloproteinases generate angiostatin: effects on neovascularization

1 reference

12 December 2020

Aberrant promoter methylation in bronchial epithelium and sputum from current and former smokers.

1 reference

12 December 2020

Relationship between polymorphisms of genes encoding microsomal epoxide hydrolase and glutathione S-transferase P1 and chronic obstructive pulmonary disease.

1 reference

12 December 2020

Aberrant promoter methylation of multiple genes in non-small cell lung cancers.

1 reference

12 December 2020

Identifiers

DOI

10.1038/NRC3477

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Dimensions Publication ID

1 August 2017

1001489764

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