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Role of 5 alpha-reductase in health and disease
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed publication ID
8092979
retrieved
1 August 2017
review article
1 reference
stated in
Europe PubMed Central
title
Role of 5 alpha-reductase in health and disease
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
8092979
retrieved
1 August 2017
author name string
Randall VA
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
8092979
retrieved
1 August 2017
publication date
1 April 1994
1 reference
stated in
Europe PubMed Central
PubMed publication ID
8092979
retrieved
1 August 2017
published in
Bailliere's clinical endocrinology and metabolism
1 reference
stated in
Europe PubMed Central
PubMed publication ID
8092979
retrieved
1 August 2017
volume
8
1 reference
stated in
Europe PubMed Central
PubMed publication ID
8092979
retrieved
1 August 2017
issue
2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
8092979
retrieved
1 August 2017
page(s)
405-431
1 reference
stated in
Europe PubMed Central
PubMed publication ID
8092979
retrieved
1 August 2017
cites work
Familial male pseudohermaphroditism due to 5-alpha-reductase deficiency in a Turkish village
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0950-351X%2805%2980259-9
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7 January 2021
based on heuristic
inferred from DOI database lookup
Deletion of steroid 5 alpha-reductase 2 gene in male pseudohermaphroditism
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0950-351X%2805%2980259-9
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7 January 2021
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A prostatic cytosol receptor
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Crossref
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https://api.crossref.org/works/10.1016%2FS0950-351X%2805%2980259-9
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7 January 2021
based on heuristic
inferred from DOI database lookup
The development of human benign prostatic hyperplasia with age
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0950-351X%2805%2980259-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of masculine differentiation in male offspring of rabbits actively immunised against testosterone before pregnancy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0950-351X%2805%2980259-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The metabolism of testosterone by human male scalp skin.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0950-351X%2805%2980259-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Kinetic parameters of 5 alpha-reductase activity in stroma and epithelium of normal, hyperplastic, and carcinomatous human prostates.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0950-351X%2805%2980259-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Variable expression of 5 alpha-reductase deficiency: presentation with male phenotype in a child of Greek origin
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0950-351X%2805%2980259-9
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7 January 2021
based on heuristic
inferred from DOI database lookup
Steroid receptor family: structure and functions
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0950-351X%2805%2980259-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Localization of androgen receptors in human skin by immunohistochemistry: implications for the hormonal regulation of hair growth, sebaceous glands and sweat glands
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0950-351X%2805%2980259-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Critical developmental periods for effects on male rat genitalia induced by finasteride, a 5 alpha-reductase inhibitor.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0950-351X%2805%2980259-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Biochemical investigations of separated epithelium and stroma from benign hyperplastic prostatic tissue
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0950-351X%2805%2980259-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hair growth effects of oral administration of finasteride, a steroid 5 alpha-reductase inhibitor, alone and in combination with topical minoxidil in the balding stumptail macaque
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0950-351X%2805%2980259-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Functional characteristics of nuclear 5 alpha-reductase from rat ventral prostate
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0950-351X%2805%2980259-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Finasteride: a slow-binding 5 alpha-reductase inhibitor.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0950-351X%2805%2980259-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Finasteride (MK-906) in the treatment of benign prostatic hyperplasia. The Finasteride Study Group
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0950-351X%2805%2980259-9
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7 January 2021
based on heuristic
inferred from DOI database lookup
Compared intracellular localization of the glucocorticosteroid and progesterone receptors: an immunocytochemical study
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0950-351X%2805%2980259-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Androgen receptors are similar in fetal and adult rabbits
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0950-351X%2805%2980259-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The effect of finasteride in men with benign prostatic hyperplasia. The Finasteride Study Group
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0950-351X%2805%2980259-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dihydrotestosterone binding by cultured human fibroblasts. Comparison of cells from control subjects and from patients with hereditary male pseudohermaphroditism due to androgen resistance
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0950-351X%2805%2980259-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Testosterone at high concentrations interacts with the human androgen receptor similarly to dihydrotestosterone
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0950-351X%2805%2980259-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The sambia ?turnim-man?: Sociocultural and clinical aspects of gender formation in male pseudohermaphrodites with 5-alpha-reductase deficiency in Papua New Guinea
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0950-351X%2805%2980259-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Expression of 5 alpha-reductase in bacteria as a trp E fusion protein and its use in the production of antibodies for immunocytochemical localization of 5 alpha-reductase.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0950-351X%2805%2980259-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Comparison of nuclear 5 alpha-reductase activities in the stromal and epithelial fractions of human prostatic tissue
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0950-351X%2805%2980259-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Studies of the nuclear 5α-reductase of human prostatic tissue: comparison of enzyme activites in hyperplastic, malignant, and normal tissues
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0950-351X%2805%2980259-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Steroid 5alpha-reductase deficiency in man: an inherited form of male pseudohermaphroditism
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0950-351X%2805%2980259-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Male pseudohermaphroditism secondary to 5α-reductase deficiency—A model for the role of androgens in both the development of the male phenotype and the evolution of a male gender identity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0950-351X%2805%2980259-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Steroid 5 alpha-reductase deficiency in a 65-year-old male pseudohermaphrodite: the natural history, ultrastructure of the testes, and evidence for inherited enzyme heterogeneity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0950-351X%2805%2980259-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The development of a male pseudohermaphroditic rat using an inhibitor of the enzyme 5 alpha-reductase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0950-351X%2805%2980259-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Decreased urinary C19 and C21 steroid 5 alpha-metabolites in parents of male pseudohermaphrodites with 5 alpha-reductase deficiency: detection of carriers
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0950-351X%2805%2980259-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The coexistence of male pseudohermaphrodites with 17-ketosteroid reductase deficiency and 5 alpha-reductase deficiency within a Turkish kindred
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0950-351X%2805%2980259-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A cluster of male pseudohermaphrodites with 5α-reductase deficiency in Papua New Guinea
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0950-351X%2805%2980259-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
5 alpha-reductase activity in cultured human dermal papilla cells from beard compared with reticular dermal fibroblasts
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0950-351X%2805%2980259-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Characterization of 5 alpha-reductase in cultured human dermal papilla cells from beard and occipital scalp hair
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0950-351X%2805%2980259-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mechanism of Action of Androgen in Dermal Papilla Cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0950-351X%2805%2980259-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Genetic and pharmacological evidence for more than one human steroid 5 alpha-reductase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0950-351X%2805%2980259-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The metabolism of testosterone by human skin in disorders of hair growth.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0950-351X%2805%2980259-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nonsteroidal inhibitors of human type I steroid 5-alpha-reductase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0950-351X%2805%2980259-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Antimüllerian hormone: new perspectives for a sexist molecule
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0950-351X%2805%2980259-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Syndrome of androgen insensitivity in man: absence of 5 alpha-dihydrotestosterone binding protein in skin fibroblasts
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0950-351X%2805%2980259-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A mutation that causes lability of the androgen receptor under conditions that normally promote transformation to the DNA-binding state
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0950-351X%2805%2980259-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Androgen production and skin metabolism in hirsutism
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0950-351X%2805%2980259-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hereditary Male Pseudohermaphroditism Associated with an Unstable Form of 5α-Reductase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0950-351X%2805%2980259-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cloning of Human Androgen Receptor Complementary DNA and Localization to the X Chromosome
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0950-351X%2805%2980259-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Classification of the types of androgenetic alopecia (common baldness) occurring in the female sex.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0950-351X%2805%2980259-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Finasteride, an inhibitor of 5 alpha-reductase, suppresses prostatic dihydrotestosterone in men with benign prostatic hyperplasia
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0950-351X%2805%2980259-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular defects in the androgen receptor causing androgen resistance
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0950-351X%2805%2980259-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role of testosterone binding to the androgen receptor in male sexual differentiation of patients with 5α-reductase deficiency
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0950-351X%2805%2980259-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Variations in pattern of pubertal changes in girls
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0950-351X%2805%2980259-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Studies on the possible existence of two 5 alpha-reductases in the rat prostate
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0950-351X%2805%2980259-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The culture of dermal papilla cells from human hair follicles
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0950-351X%2805%2980259-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Biological Actions of Androgens
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0950-351X%2805%2980259-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of testosterone-induced sexual behavior in the castrated male rat by aromatase blockers
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0950-351X%2805%2980259-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Male pseudohermaphroditism due to steroid 5-alpha-reductase deficiency
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0950-351X%2805%2980259-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Androgens and human hair growth
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0950-351X%2805%2980259-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Is the metabolism of testosterone to 5 alpha-dihydrotestosterone required for androgen action in the skin?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0950-351X%2805%2980259-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
In-vivo uptake and metabolism of testosterone by the skin and other tissues of the rat
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0950-351X%2805%2980259-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mechanism of androgen action in cultured dermal papilla cells derived from human hair follicles with varying responses to androgens in vivo
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0950-351X%2805%2980259-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cultured dermal papilla cells from androgen-dependent human hair follicles (e.g. beard) contain more androgen receptors than those from non-balding areas of scalp
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0950-351X%2805%2980259-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hormones and hair growth: variations in androgen receptor content of dermal papilla cells cultured from human and red deer (Cervus elaphus) hair follicles.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0950-351X%2805%2980259-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Comparison of finasteride (Proscar), a 5 alpha reductase inhibitor, and various commercial plant extracts in in vitro and in vivo 5 alpha reductase inhibition
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0950-351X%2805%2980259-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The effects of N,N-diethyl-4-methyl-3-oxo-4-aza-5 alpha-androstane-17 beta-carboxamide, a 5 alpha-reductase inhibitor and antiandrogen, on the development of baldness in the stumptail macaque
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0950-351X%2805%2980259-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Prepubertal diagnosis of steroid 5 alpha-reductase deficiency
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0950-351X%2805%2980259-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differential rates of conversion of testosterone to dihydrotestosterone in acne and in normal human skin--a possible pathogenic factor in acne
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0950-351X%2805%2980259-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
5 alpha-Reductase activity in the genital skin of hirsute women
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0950-351X%2805%2980259-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Testosterone formation and metabolism during male sexual differentiation in the human embryo
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0950-351X%2805%2980259-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activity of testosterone 5 alpha-reductase in various tissues of human skin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0950-351X%2805%2980259-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The influence of finasteride on the volume of the peripheral and periurethral zones of the prostate in men with benign prostatic hyperplasia
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0950-351X%2805%2980259-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular genetics of steroid 5 alpha-reductase 2 deficiency
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0950-351X%2805%2980259-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Brief report: the molecular basis of steroid 5 alpha-reductase deficiency in a large Dominican kindred
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0950-351X%2805%2980259-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tissue distribution and ontogeny of steroid 5 alpha-reductase isozyme expression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0950-351X%2805%2980259-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differences in testosterone metabolism by beard and scalp hair follicle dermal papilla cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0950-351X%2805%2980259-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cloning, structure and expression of a cDNA encoding the human androgen receptor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0950-351X%2805%2980259-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Familial incomplete male pseudohermaphroditism, type 2. Decreased dihydrotestosterone formation in pseudovaginal perineoscrotal hypospadias.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0950-351X%2805%2980259-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dihydrotestosterone Formation in Fetal Tissues of the Rabbit and Rat
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0950-351X%2805%2980259-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0950-351X(05)80259-9
1 reference
stated in
Europe PubMed Central
PubMed publication ID
8092979
retrieved
1 August 2017
PubMed publication ID
8092979
1 reference
stated in
Europe PubMed Central
PubMed publication ID
8092979
retrieved
1 August 2017
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