(Q34339449)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25307742%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

title

Integrated control of hepatic lipogenesis versus glucose production requires FoxO transcription factors (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25307742%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25307742%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

Joshua R Cook

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25307742%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

author name string

Kirsten Hartil

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25307742%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

Bhavapriya Vaitheesvaran

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25307742%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

Isabel Arrieta-Cruz

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25307742%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

Colette M Knight

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25307742%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

Helene L Kammoun

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25307742%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

Mark A Febbraio

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25307742%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

Roger Gutierrez-Juarez

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25307742%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

Irwin J Kurland

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25307742%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

Domenico Accili

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25307742%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

language of work or name

English

0 references

publication date

13 October 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25307742%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

published in

Nature Communications

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25307742%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

volume

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25307742%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

page(s)

5190

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25307742%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/ncomms6190

21 February 2020

exact match

0 references

cites work

Antidiabetic effects of glucokinase regulatory protein small-molecule disruptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4197140

Deletion of hepatic FoxO1/3/4 genes in mice significantly impacts on glucose metabolism through downregulation of gluconeogenesis and upregulation of glycolysis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4197140

The design and synthesis of indazole and pyrazolopyridine based glucokinase activators for the treatment of type 2 diabetes mellitus

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4197140

Hepatic FoxO1 integrates glucose utilization and lipid synthesis through regulation of Chrebp O-glycosylation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4197140

Plasma lysophosphatidylcholine levels are reduced in obesity and type 2 diabetes.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4197140

Hepatic insulin signaling is required for obesity-dependent expression of SREBP-1c mRNA but not for feeding-dependent expression

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4197140

Hepatic Hdac3 promotes gluconeogenesis by repressing lipid synthesis and sequestration

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4197140

Calcium signaling through CaMKII regulates hepatic glucose production in fasting and obesity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4197140

Effects of a glucokinase activator on hepatic intermediary metabolism: study with 13C-isotopomer-based metabolomics

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4197140

Peripheral effects of FAAH deficiency on fuel and energy homeostasis: role of dysregulated lysine acetylation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4197140

Mechanisms for insulin resistance: common threads and missing links

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4197140

Insulin regulates liver metabolism in vivo in the absence of hepatic Akt and Foxo1

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4197140

Impaired generation of 12-hydroxylated bile acids links hepatic insulin signaling with dyslipidemia

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4197140

Hepatic suppression of Foxo1 and Foxo3 causes hypoglycemia and hyperlipidemia in mice

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4197140

Akt stimulates hepatic SREBP1c and lipogenesis through parallel mTORC1-dependent and independent pathways

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4197140

Hormonal regulation of hepatic glucose production in health and disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4197140

Hepatic FoxOs regulate lipid metabolism via modulation of expression of the nicotinamide phosphoribosyltransferase gene

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4197140

FoxOs function synergistically to promote glucose production

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4197140

Hepatic FoxO1 ablation exacerbates lipid abnormalities during hyperglycemia

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4197140

Uncoupling of acetylation from phosphorylation regulates FoxO1 function independent of its subcellular localization.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4197140

Bifurcation of insulin signaling pathway in rat liver: mTORC1 required for stimulation of lipogenesis, but not inhibition of gluconeogenesis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4197140

Fasting hyperglycemia is not associated with increased expression of PEPCK or G6Pc in patients with Type 2 Diabetes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4197140

Assessing the potential of glucokinase activators in diabetes therapy

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4197140

SREBP activity is regulated by mTORC1 and contributes to Akt-dependent cell growth

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4197140

Inactivation of hepatic Foxo1 by insulin signaling is required for adaptive nutrient homeostasis and endocrine growth regulation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4197140

Selective versus total insulin resistance: a pathogenic paradox

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4197140

FoxO1 protects against pancreatic beta cell failure through NeuroD and MafA induction

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4197140

Restoration of liver insulin signaling in Insr knockout mice fails to normalize hepatic insulin action

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4197140

Decreased IRS-2 and increased SREBP-1c lead to mixed insulin resistance and sensitivity in livers of lipodystrophic and ob/ob mice

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4197140

Dual roles for glucokinase in glucose homeostasis as determined by liver and pancreatic beta cell-specific gene knock-outs using Cre recombinase

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4197140

Impaired hepatic glycogen synthesis in glucokinase-deficient (MODY-2) subjects

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4197140

The development of hepatic glucokinase in the neonatal rat.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4197140

Molecular cloning of glucokinase cDNA. Developmental and dietary regulation of glucokinase mRNA in rat liver

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4197140

Impaired regulation of hepatic glucose production in mice lacking the forkhead transcription factor Foxo1 in liver.

6 July 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6190

High-resolution dynamics of the transcriptional response to nutrition in Drosophila: a key role for dFOXO.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6190

FoxO1 regulates multiple metabolic pathways in the liver: effects on gluconeogenic, glycolytic, and lipogenic gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6190

Metabolic impact of glucokinase overexpression in liver: lowering of blood glucose in fed rats is accompanied by hyperlipidemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6190

Allosteric activators of glucokinase: potential role in diabetes therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6190

A combination of HNF-4 and Foxo1 is required for reciprocal transcriptional regulation of glucokinase and glucose-6-phosphatase genes in response to fasting and feeding.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6190

Decreased hepatic futile cycling compensates for increased glucose disposal in the Pten heterodeficient mouse.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6190

Determination of a glucose-dependent futile recycling rate constant from an intraperitoneal glucose tolerance test

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6190

Long-term overexpression of glucokinase in the liver of transgenic mice leads to insulin resistance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6190

Insulin resistance in non-diabetic patients with non-alcoholic fatty liver disease: sites and mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6190

The loss of postprandial glycemic control precedes stepwise deterioration of fasting with worsening diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6190

Diabetes affects similarly the catalytic subunit and putative glucose-6-phosphate translocase of glucose-6-phosphatase

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25307742

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Glucose administration induces the premature expression of liver glucokinase gene in newborn rats. Relation with DNase-I-hypersensitive sites

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25307742

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Evidence from transgenic mice that glucokinase is rate limiting for glucose utilization in the liver

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25307742

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NCOMMS6190

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25307742%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

21 February 2020

ADS bibcode

2014NatCo...5.5190H

0 references

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25307742%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25307742%20AND%20SRC:MED&resulttype=core&format=json