(Q34345195)

1 August 2017

title

Blocking LINGO-1 as a therapy to promote CNS repair: from concept to the clinic (English)

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1 August 2017

Sha Mi

1

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1 August 2017

R Blake Pepinsky

series ordinal

2

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1 August 2017

Diego Cadavid

series ordinal

3

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1 August 2017

publication date

1 July 2013

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1 August 2017

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1 August 2017

volume

27

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1 August 2017

issue

7

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1 August 2017

page(s)

493-503

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Priorities in Parkinson's disease research

1 August 2017

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AMIGO, a transmembrane protein implicated in axon tract development, defines a novel protein family with leucine-rich repeats

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Multiple roles for slits in the control of cell migration in the rostral migratory stream

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Identification of a receptor mediating Nogo-66 inhibition of axonal regeneration

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The Nogo-66 receptor: focusing myelin inhibition of axon regeneration

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LINGO-1 is a component of the Nogo-66 receptor/p75 signaling complex

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LINGO-1 negatively regulates myelination by oligodendrocytes

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Promotion of central nervous system remyelination by induced differentiation of oligodendrocyte precursor cells

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Inhibition of the leucine-rich repeat protein LINGO-1 enhances survival, structure, and function of dopaminergic neurons in Parkinson's disease models

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Blocking LINGO-1 function promotes retinal ganglion cell survival following ocular hypertension and optic nerve transection.

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LINGO-1 negatively regulates TrkB phosphorylation after ocular hypertension.

21 January 2018

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Combined effect of brain-derived neurotrophic factor and LINGO-1 fusion protein on long-term survival of retinal ganglion cells in chronic glaucoma.

21 January 2018

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LINGO-1 and its role in CNS repair

21 January 2018

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Expression profile of receptors for myelin-associated inhibitors of axonal regeneration in the intact and injured mouse central nervous system

21 January 2018

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LRRN6A/LERN1 (leucine-rich repeat neuronal protein 1), a novel gene with enriched expression in limbic system and neocortex.

21 January 2018

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Expression pattern of LINGO-1 in the developing nervous system of the chick embryo

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The neurobiology of multiple sclerosis: genes, inflammation, and neurodegeneration

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Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis

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Remyelination of the demyelinated CNS: the case for and against transplantation of central, peripheral and olfactory glia

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Premyelinating oligodendrocytes in chronic lesions of multiple sclerosis

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Chondroitin sulfate proteoglycans in demyelinated lesions impair remyelination.

21 January 2018

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Myelin impairs CNS remyelination by inhibiting oligodendrocyte precursor cell differentiation

21 January 2018

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Dysregulation of the Wnt pathway inhibits timely myelination and remyelination in the mammalian CNS

21 January 2018

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Notch1 signaling plays a role in regulating precursor differentiation during CNS remyelination.

21 January 2018

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NGF controls axonal receptivity to myelination by Schwann cells or oligodendrocytes

21 January 2018

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Axon loss is responsible for chronic neurological deficit following inflammatory demyelination in the rat.

21 January 2018

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Exposure levels of anti-LINGO-1 Li81 antibody in the central nervous system and dose-efficacy relationships in rat spinal cord remyelination models after systemic administration.

21 January 2018

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Anatomy of "regenerating axons".

21 January 2018

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A TNF receptor family member, TROY, is a coreceptor with Nogo receptor in mediating the inhibitory activity of myelin inhibitors

21 January 2018

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TAJ/TROY, an orphan TNF receptor family member, binds Nogo-66 receptor 1 and regulates axonal regeneration

21 January 2018

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Ex vivo gene delivery of GDNF using primary astrocytes transduced with a lentiviral vector provides neuroprotection in a rat model of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40263-013-0068-8

Heparin-binding epidermal growth factor-like growth factor: a component in chromaffin granules which promotes the survival of nigrostriatal dopaminergic neurones in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40263-013-0068-8

Influences of dopaminergic lesion on epidermal growth factor-ErbB signals in Parkinson's disease and its model: neurotrophic implication in nigrostriatal neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40263-013-0068-8

Survival factors for treatment of retinal degenerative disorders: preclinical gains and issues for translation into clinical studies

21 January 2018

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Neurotrophins and peripheral neuropathies

21 January 2018

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Nerve growth factor and chronic daily headache: a potential implication for therapy

21 January 2018

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Crossroads in GDNF therapy for Parkinson's disease

21 January 2018

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Nerve growth factor gene therapy in Alzheimer disease

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21 January 2018

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Platelet-derived growth factor regulates oligodendrocyte progenitor numbers in adult CNS and their response following CNS demyelination.

21 January 2018

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Ciliary neurotrophic factor for acceleration of peripheral nerve regeneration: an experimental study

21 January 2018

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LINGO-1 antagonist promotes spinal cord remyelination and axonal integrity in MOG-induced experimental autoimmune encephalomyelitis

21 January 2018

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[Neurotrophins. II: therapeutic potential]

21 January 2018

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12 December 2020

NGF regulates the expression of axonal LINGO-1 to inhibit oligodendrocyte differentiation and myelination

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12 December 2020

LINGO-1 antagonists as therapy for multiple sclerosis: in vitro and in vivo evidence

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12 December 2020

Ciliary neurotrophic factor (CNTF) for amyotrophic lateral sclerosis or motor neuron disease

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12 December 2020

LINGO-1 antagonist promotes functional recovery and axonal sprouting after spinal cord injury

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12 December 2020

Hyaluronan accumulates in demyelinated lesions and inhibits oligodendrocyte progenitor maturation.

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12 December 2020

Riluzole for amyotrophic lateral sclerosis (ALS)/motor neuron disease (MND)

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12 December 2020

Epidermal growth factor receptor-dependent Akt activation by oxidative stress enhances cell survival

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12 December 2020

Passive immunization with LINGO-1 polyclonal antiserum afforded neuroprotection and promoted functional recovery in a rat model of spinal cord injury

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12 December 2020

Understanding CNS remyelination: clues from developmental and regeneration biology

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12 December 2020

Retinal ganglion cell death in experimental glaucoma and after axotomy occurs by apoptosis

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12 December 2020

Expression of EGF receptor mRNA in rat nigrostriatal system

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12 December 2020

10.1007/S40263-013-0068-8

Identifiers

DOI

1 reference

1 August 2017

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