(Q34347885)

1 August 2017

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title

Quinolone molecular structure-activity relationships: what we have learned about improving antimicrobial activity (English)

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1 August 2017

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Peterson LR

1

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PubMed ID

11524717

1 August 2017

language of work or name

English

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publication date

1 September 2001

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Clinical Infectious Diseases

1 August 2017

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1 August 2017

33 Suppl 3

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1 August 2017

S180-6

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The prospects of treatment failure in the chemotherapy of infectious diseases in the 1990s.

1 August 2017

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Trends in infectious diseases mortality in the United States

21 January 2018

1 reference

Risk factors for acquisition of levofloxacin-resistant Streptococcus pneumoniae: a case-control study

21 January 2018

1 reference

Fluoroquinolone toxicity profiles: a review focusing on newer agents

21 January 2018

1 reference

Quinolones: structure-activity relationships and future predictions

21 January 2018

1 reference

Bacterial topoisomerases, anti-topoisomerases, and anti-topoisomerase resistance.

21 January 2018

1 reference

Crystal structure of the breakage-reunion domain of DNA gyrase

21 January 2018

1 reference

Selective targeting of topoisomerase IV and DNA gyrase in Staphylococcus aureus: different patterns of quinolone-induced inhibition of DNA synthesis

21 January 2018

1 reference

Analysis of gyrA and grlA mutations in stepwise-selected ciprofloxacin-resistant mutants of Staphylococcus aureus

21 January 2018

1 reference

Cloning and characterization of the parC and parE genes of Streptococcus pneumoniae encoding DNA topoisomerase IV: role in fluoroquinolone resistance

21 January 2018

1 reference

Quinolone resistance by mutations in chromosomal gyrase genes. Just the tip of the iceberg?

21 January 2018

1 reference

Efflux-mediated fluoroquinolone resistance in Staphylococcus aureus

21 January 2018

1 reference

Fluoroquinolone resistance protein NorA of Staphylococcus aureus is a multidrug efflux transporter

21 January 2018

1 reference

Nucleotide sequence and characterization of the Staphylococcus aureus norA gene, which confers resistance to quinolones

21 January 2018

1 reference

Mechanism of action of sparfloxacin against and mechanism of resistance in gram-negative and gram-positive bacteria

21 January 2018

1 reference

The role of outer membrane and efflux pumps in the resistance of gram-negative bacteria. Can we improve drug access?

21 January 2018

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Mechanisms involved in the development of resistance to fluoroquinolones in Escherichia coli isolates.

21 January 2018

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Structure-activity and structure-side-effect relationships for the quinolone antibacterials

21 January 2018

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Studies on quinolone antibacterials. IV. Structure-activity relationships of antibacterial activity and side effects for 5- or 8-substituted and 5,8-disubstituted-7-(3-amino-1-pyrrolidinyl)-1-cyclopropyl-1, 4-dihydro-4-oxoquinoline-3-carboxylic acid

21 January 2018

1 reference

Novelties in the field of anti-infectives in 1998.

21 January 2018

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Intracellular targets of moxifloxacin: a comparison with other fluoroquinolones

21 January 2018

1 reference

A convenient assay for estimating the possible involvement of efflux of fluoroquinolones by Streptococcus pneumoniae and Staphylococcus aureus: evidence for diminished moxifloxacin, sparfloxacin, and trovafloxacin efflux.

21 January 2018

1 reference

Antipneumococcal activities of gemifloxacin compared to those of nine other agents

21 January 2018

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DNA topoisomerase targets of the fluoroquinolones: a strategy for avoiding bacterial resistance

21 January 2018

1 reference

Contributions of the 8-methoxy group of gatifloxacin to resistance selectivity, target preference, and antibacterial activity against Streptococcus pneumoniae

21 January 2018

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Structure, function and controls in microbial division

21 January 2018

1 reference

Chemometric Methodologies in a Quantitative Structure−Activity Relationship Study: The Antibacterial Activity of 6-Aminoquinolones

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1086/321846

1 reference

1 August 2017

1 reference

PubMed ID

11524717