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Signaling through receptors and scaffolds: independent interactions reduce combinatorial complexity
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Europe PubMed Central
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1366644
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15923229%20AND%20SRC:MED&resulttype=core&format=json
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12 January 2020
title
Signaling through receptors and scaffolds: independent interactions reduce combinatorial complexity
(English)
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12 January 2020
author
Boris Kholodenko
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4
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12 January 2020
Jan B. Hoek
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3
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12 January 2020
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Nikolay M Borisov
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1
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12 January 2020
Nick I Markevich
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2
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12 January 2020
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English
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publication date
27 May 2005
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12 January 2020
published in
Biophysical Journal
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1366644
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12 January 2020
volume
89
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12 January 2020
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2
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12 January 2020
page(s)
951-966
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1366644
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12 January 2020
cites work
Signal processing at the Ras circuit: what shapes Ras activation patterns?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1366644
retrieved
6 July 2018
Automatic generation of cellular reaction networks with Moleculizer 1.0.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1366644
retrieved
6 July 2018
BioNetGen: software for rule-based modeling of signal transduction based on the interactions of molecular domains
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1366644
retrieved
6 July 2018
Mathematical and computational models of immune-receptor signalling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1366644
retrieved
6 July 2018
Signaling switches and bistability arising from multisite phosphorylation in protein kinase cascades
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1366644
retrieved
6 July 2018
The complexity of complexes in signal transduction.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1366644
retrieved
6 July 2018
Next generation simulation tools: the Systems Biology Workbench and BioSPICE integration
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1366644
retrieved
6 July 2018
The role of Gab family scaffolding adapter proteins in the signal transduction of cytokine and growth factor receptors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1366644
retrieved
6 July 2018
Molecular Mechanism for a Role of SHP2 in Epidermal Growth Factor Receptor Signaling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1366644
retrieved
6 July 2018
Akt as a mediator of cell death
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1366644
retrieved
6 July 2018
Src phosphorylates Grb2-associated binder 1 upon hepatocyte growth factor stimulation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1366644
retrieved
6 July 2018
Growth factor receptor-binding protein 10 (Grb10) as a partner of phosphatidylinositol 3-kinase in metabolic insulin action
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1366644
retrieved
6 July 2018
A computational model on the modulation of mitogen-activated protein kinase (MAPK) and Akt pathways in heregulin-induced ErbB signalling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1366644
retrieved
6 July 2018
Control, exploitation and tolerance of intracellular noise
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1366644
retrieved
6 July 2018
Structural biology of insulin and IGF1 receptors: implications for drug design
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1366644
retrieved
6 July 2018
IRS proteins and the common path to diabetes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1366644
retrieved
6 July 2018
Receptor-specific regulation of phosphatidylinositol 3'-kinase activation by the protein tyrosine phosphatase Shp2.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1366644
retrieved
6 July 2018
Computational modeling of the dynamics of the MAP kinase cascade activated by surface and internalized EGF receptors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1366644
retrieved
6 July 2018
SHP-2 is involved in heterodimer specific loss of phosphorylation of Tyr771 in the PDGF beta-receptor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1366644
retrieved
6 July 2018
Insulin signaling pathways in time and space.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1366644
retrieved
6 July 2018
SH2 domains, interaction modules and cellular wiring
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1366644
retrieved
6 July 2018
STOCHSIM: modelling of stochastic biomolecular processes.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1366644
retrieved
6 July 2018
Activation of the insulin receptor's kinase domain changes the rate-determining step of substrate phosphorylation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1366644
retrieved
6 July 2018
Cell signaling by receptor tyrosine kinases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1366644
retrieved
6 July 2018
Molecular model of a lattice of signalling proteins involved in bacterial chemotaxis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1366644
retrieved
6 July 2018
Mechanism of transmembrane signaling: insulin binding and the insulin receptor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1366644
retrieved
6 July 2018
Identification of major tyrosine phosphorylation sites in the human insulin receptor substrate Gab-1 by insulin receptor kinase in vitro
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1366644
retrieved
6 July 2018
Scaffold proteins may biphasically affect the levels of mitogen-activated protein kinase signaling and reduce its threshold properties
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1366644
retrieved
6 July 2018
A novel positive feedback loop mediated by the docking protein Gab1 and phosphatidylinositol 3-kinase in epidermal growth factor receptor signaling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1366644
retrieved
6 July 2018
Signaling--2000 and beyond
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1366644
retrieved
6 July 2018
Internalized epidermal growth factor receptors participate in the activation of p21(ras) in fibroblasts
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1366644
retrieved
6 July 2018
Effect of epidermal growth factor receptor internalization on regulation of the phospholipase C-gamma1 signaling pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1366644
retrieved
6 July 2018
The Gab1 protein is a docking site for multiple proteins involved in signaling by the B cell antigen receptor.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1366644
retrieved
6 July 2018
The IRS-signalling system: a network of docking proteins that mediate insulin action
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1366644
retrieved
6 July 2018
Control analysis of metabolic systems involving quasi-equilibrium reactions
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1366644
retrieved
6 July 2018
Mechanistic studies of the dual phosphorylation of mitogen-activated protein kinase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1366644
retrieved
6 July 2018
YMXM motifs and signaling by an insulin receptor substrate 1 molecule without tyrosine phosphorylation sites
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1366644
retrieved
6 July 2018
Interaction between the insulin receptor and its downstream effectors. Use of individually expressed receptor domains for structure/function analysis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1366644
retrieved
6 July 2018
Metabolic regulation and mathematical models
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1366644
retrieved
6 July 2018
Investigation of early events in Fc epsilon RI-mediated signaling using a detailed mathematical model
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1366644
retrieved
27 October 2018
The structural biology of growth factor receptor activation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1366644
retrieved
27 October 2018
Temperature dependence of the epidermal growth factor receptor signaling network can be accounted for by a kinetic model
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1366644
retrieved
27 October 2018
The mechanism of dephosphorylation of extracellular signal-regulated kinase 2 by mitogen-activated protein kinase phosphatase 3.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1366644
retrieved
27 October 2018
Phosphoinositide 3-kinase: the key switch mechanism in insulin signalling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1366644
retrieved
27 October 2018
Predicting temporal fluctuations in an intracellular signalling pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1366644
retrieved
27 October 2018
Control theory of metabolic channelling.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1366644
retrieved
27 October 2018
Localization of the insulin receptor binding sites for the SH2 domain proteins p85, Syp, and GAP.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1366644
retrieved
27 October 2018
Gab1 is required for EGF receptor signaling and the transformation by activated ErbB2
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1366644
retrieved
27 October 2018
Presence of Oxidized Cholesterol in Caveolae Uncouples Active Platelet-derived Growth Factor Receptors from Tyrosine Kinase Substrates
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1366644
retrieved
9 December 2018
The kinetics of bivalent ligand-bivalent receptor aggregation: ring formation and the breakdown of the equivalent site approximation
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/15923229
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
An evaluation of the cross-linking model for the interaction of insulin with its receptor
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/15923229
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Quantification of Short Term Signaling by the Epidermal Growth Factor Receptor
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/15923229
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Epidermal Growth Factor-induced DNA Synthesis
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/15923229
retrieved
12 December 2020
based on heuristic
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Identifiers
DOI
10.1529/BIOPHYSJ.105.060533
1 reference
stated in
Europe PubMed Central
PMC publication ID
1366644
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15923229%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 January 2020
PMC publication ID
1366644
1 reference
stated in
Europe PubMed Central
PMC publication ID
1366644
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15923229%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 January 2020
PubMed publication ID
15923229
1 reference
stated in
Europe PubMed Central
PMC publication ID
1366644
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15923229%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 January 2020
ResearchGate publication ID
7819125
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