(Q34351021)

1 August 2017

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title

Triplex-forming molecules: from concepts to applications (English)

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1 August 2017

Faria M

1

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PubMed ID

11529659

1 August 2017

Giovannangeli C

series ordinal

2

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PubMed ID

11529659

1 August 2017

language of work or name

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1 July 2001

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1 August 2017

Journal of Gene Medicine

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1 August 2017

3

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1 August 2017

4

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1 August 2017

299-310

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Sequence-specific recognition, photocrosslinking and cleavage of the DNA double helix by an oligo-[alpha]-thymidylate covalently linked to an azidoproflavine derivative

1 August 2017

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Sequence-specific cleavage of double helical DNA by triple helix formation.

21 January 2018

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Disruption of IRS-2 causes type 2 diabetes in mice

21 January 2018

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Inhibition of RNA polymerase II transcription in human cells by synthetic DNA-binding ligands

21 January 2018

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Activation of gene expression by small molecule transcription factors

21 January 2018

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Comprehensive DNA recognition through concerted interactions from adjacent zinc fingers

21 January 2018

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Getting a handhold on DNA: design of poly-zinc finger proteins with femtomolar dissociation constants.

21 January 2018

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Toward controlling gene expression at will: specific regulation of the erbB-2/HER-2 promoter by using polydactyl zinc finger proteins constructed from modular building blocks

21 January 2018

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Positive and negative regulation of endogenous genes by designed transcription factors

21 January 2018

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Triple helix formation by (G,A)-containing oligonucleotides: asymmetric sequence effect

21 January 2018

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Stability of G,A triple helices

21 January 2018

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Energetics of strand-displacement reactions in triple helices: a spectroscopic study.

21 January 2018

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Competitive triplex/quadruplex equilibria involving guanine-rich oligonucleotides

21 January 2018

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A new approach to overcome potassium-mediated inhibition of triplex formation

21 January 2018

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Effect of competing self-structure on triplex formation with purine-rich oligodeoxynucleotides containing GA repeats

21 January 2018

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Potassium-resistant triple helix formation and improved intracellular gene targeting by oligodeoxyribonucleotides containing 7-deazaxanthine

21 January 2018

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Stable triple helices formed by oligonucleotide N3'-->P5' phosphoramidates inhibit transcription elongation

21 January 2018

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Positively charged oligonucleotides overcome potassium-mediated inhibition of triplex DNA formation.

21 January 2018

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Targeted inhibition of transcription elongation in cells mediated by triplex-forming oligonucleotides

21 January 2018

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Understanding oligonucleotide-mediated inhibition of gene expression in Xenopus laevis oocytes

21 January 2018

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Antileukemia effect of c-myc N3'-->P5' phosphoramidate antisense oligonucleotides in vivo

21 January 2018

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Peptide nucleic acid-targeted mutagenesis of a chromosomal gene in mouse cells

21 January 2018

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Peptide nucleic acid (PNA) binding-mediated induction of human gamma-globin gene expression

21 January 2018

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Cell penetrating PNA constructs regulate galanin receptor levels and modify pain transmission in vivo

21 January 2018

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Accessibility of nuclear DNA to triplex-forming oligonucleotides: the integrated HIV-1 provirus as a target

21 January 2018

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Inhibition of gene expression by triple helix-directed DNA cross-linking at specific sites.

21 January 2018

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Blocking transcription of the human rhodopsin gene by triplex-mediated DNA photocrosslinking

21 January 2018

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Unambiguous demonstration of triple-helix-directed gene modification

21 January 2018

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Psoralen adducts induced by triplex-forming oligonucleotides are refractory to repair in HeLa cells

21 January 2018

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Sequence-specific recognition and cleavage of duplex DNA via triple-helix formation by oligonucleotides covalently linked to a phenanthroline-copper chelate

21 January 2018

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Rational design of a triple helix-specific intercalating ligand.

21 January 2018

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The yeast CDP1 gene encodes a triple-helical DNA-binding protein

21 January 2018

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Investigation of the intracellular stability and formation of a triple helix formed with a short purine oligonucleotide targeted to the murine c-pim-1 proto-oncogene promotor

21 January 2018

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Triplex targeting of a native gene in permeabilized intact cells: covalent modification of the gene for the chemokine receptor CCR5.

21 January 2018

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Triple helix-forming oligonucleotides target psoralen adducts to specific chromosomal sequences in human cells

21 January 2018

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The stability of DNA triplexes inside cells as studied by iodine-125 radioprinting

21 January 2018

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Evidence that a triplex-forming oligodeoxyribonucleotide binds to the c-myc promoter in HeLa cells, thereby reducing c-myc mRNA levels

21 January 2018

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C-terminal extension of truncated recombinant proteins in Escherichia coli with a 10Sa RNA decapeptide.

21 January 2018

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Triple helix-forming oligonucleotide corresponding to the polypyrimidine sequence in the rat alpha 1(I) collagen promoter specifically inhibits factor binding and transcription

21 January 2018

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Antiparallel polypurine phosphorothioate oligonucleotides form stable triplexes with the rat alpha1(I) collagen gene promoter and inhibit transcription in cultured rat fibroblasts

21 January 2018

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DNA triplex formation selectively inhibits granulocyte-macrophage colony-stimulating factor gene expression in human T cells

21 January 2018

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In vivo transcription of a progesterone-responsive gene is specifically inhibited by a triplex-forming oligonucleotide

21 January 2018

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Transcription of the human c-Src promoter is dependent on Sp1, a novel pyrimidine binding factor SPy, and can be inhibited by triplex-forming oligonucleotides

21 January 2018

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Inhibition of gene expression and cell proliferation by triple helix-forming oligonucleotides directed to the c-myc gene

21 January 2018

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In vivo persistence of DNA triple helices containing psoralen-conjugated oligodeoxyribonucleotides

21 January 2018

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Pax5 (BSAP) regulates the murine immunoglobulin 3' alpha enhancer by suppressing binding of NF-alpha P, a protein that controls heavy chain transcription

21 January 2018

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Gene activation by triplex-forming oligonucleotide coupled to the activating domain of protein VP16

21 January 2018

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Peptide nucleic acid.DNA strand displacement loops as artificial transcription promoters

21 January 2018

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Triple helix DNA alters nucleosomal histone-DNA interactions and acts as a nucleosome barrier

21 January 2018

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Suppression of insulin-like growth factor type I receptor by a triple-helix strategy inhibits IGF-I transcription and tumorigenic potential of rat C6 glioblastoma cells

21 January 2018

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In vivostability and kinetics of absorption and disposition of 3' phosphopropyl amine oligonucleotides

21 January 2018

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Mutagenesis in mammalian cells induced by triple helix formation and transcription-coupled repair

21 January 2018

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Chromosomal mutations induced by triplex-forming oligonucleotides in mammalian cells

21 January 2018

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Targeted mutagenesis in mammalian cells mediated by intracellular triple helix formation

21 January 2018

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Covalent crosslinks introduced via a triple helix-forming oligonucleotide coupled to psoralen are inefficiently repaired

21 January 2018

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Triple-helix formation induces recombination in mammalian cells via a nucleotide excision repair-dependent pathway

21 January 2018

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High-frequency intrachromosomal gene conversion induced by triplex-forming oligonucleotides microinjected into mouse cells

21 January 2018

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Targeted correction of an episomal gene in mammalian cells by a short DNA fragment tethered to a triplex-forming oligonucleotide

21 January 2018

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Correction of chromosomal point mutations in human cells with bifunctional oligonucleotides

21 January 2018

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Identification, purification and partial characterisation of an oligonucleotide receptor in membranes of HepG2 cells

21 January 2018

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Nucleocytoplasmic shuttling: a novel in vivo property of antisense phosphorothioate oligodeoxynucleotides.

21 January 2018

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Characterisation of membrane oligonucleotide-binding proteins and oligonucleotide uptake in keratinocytes

21 January 2018

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Polyethylenimine but not cationic lipid improves antisense activity of 3'-capped phosphodiester oligonucleotides

21 January 2018

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DNA damage-dependent transcriptional arrest and termination of RNA polymerase II elongation complexes in DNA template containing HIV-1 promoter

21 January 2018

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Measuring motion on DNA by the type I restriction endonuclease EcoR124I using triplex displacement

21 January 2018

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Design of artificial sequence-specific DNA bending ligands

21 January 2018

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Efficient purification of plasmid DNA for gene transfer using triple-helix affinity chromatography

21 January 2018

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Triple helix formation on plasmid DNA determined by a size-exclusion chromatographic method

21 January 2018

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Gene chemistry: functionally and conformationally intact fluorescent plasmid DNA.

21 January 2018

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Novel method for covalent fluorescent labeling of plasmid DNA that maintains structural integrity of the plasmid.

21 January 2018

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A peptide nucleic acid-nuclear localization signal fusion that mediates nuclear transport of DNA.

21 January 2018

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Coupling of a targeting peptide to plasmid DNA by covalent triple helix formation

21 January 2018

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Gene delivery: a single nuclear localization signal peptide is sufficient to carry DNA to the cell nucleus

21 January 2018

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Padlock oligonucleotides for duplex DNA based on sequence-specific triple helix formation.

21 January 2018

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Alternate strand recognition of double-helical DNA by (T,G)-containing oligonucleotides in the presence of a triple helix-specific ligand

21 January 2018

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21 January 2018

Reading the minor groove

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Effects in live cells of a c-myc anti-gene PNA linked to a nuclear localization signal

21 January 2018

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Targeting topoisomerase I cleavage to specific sequences of DNA by triple helix-forming oligonucleotide conjugates. A comparison between a rebeccamycin derivative and camptothecin

21 January 2018

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The yeast STM1 gene encodes a purine motif triple helical DNA-binding protein

21 January 2018

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Cellular nucleic acid binding protein regulates the CT element of the human c-myc protooncogene

21 January 2018

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Triple-helix formation at different positions on nucleosomal DNA

21 January 2018

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Specific mutations induced by triplex-forming oligonucleotides in mice

21 January 2018

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Targeted gene knockout mediated by triple helix forming oligonucleotides

21 January 2018

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Asymmetric recognition of psoralen interstrand crosslinks by the nucleotide excision repair and the error-prone repair pathways

21 January 2018

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Triplex technology takes off

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/JGM.192

1 reference

1 August 2017

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PubMed ID

11529659