(Q34360861)

1 August 2017

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N-substituted piperazines abused by humans mimic the molecular mechanism of 3,4-methylenedioxymethamphetamine (MDMA, or 'Ecstasy'). (English)

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1 August 2017

Michael H Baumann

1

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1 August 2017

Robert D Clark

2

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1 August 2017

Allison G Budzynski

3

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1 August 2017

John S Partilla

4

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1 August 2017

Bruce E Blough

5

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1 August 2017

Richard B Rothman

6

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1 August 2017

language of work or name

English

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publication date

1 March 2005

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1 August 2017

published in

Neuropsychopharmacology

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1 August 2017

volume

30

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1 August 2017

issue

3

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1 August 2017

page(s)

550-560

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https://scigraph.springernature.com/pub.10.1038/sj.npp.1300585

1 August 2017

exact match

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cites work

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Substituted piperazine and indole compounds increase extracellular serotonin in rat diencephalon as determined by in vivo microdialysis

21 January 2018

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Pharmacological studies of the acute effects of (+)-3,4-methylenedioxymethamphetamine on locomotor activity: role of 5-HT(1B/1D) and 5-HT(2) receptors

21 January 2018

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1-(m-chlorophenyl)piperazine (mCPP) dissociates in vivo serotonin release from long-term serotonin depletion in rat brain

21 January 2018

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Persistent antagonism of methamphetamine-induced dopamine release in rats pretreated with GBR12909 decanoate

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Facilitation of dopamine release in vivo by serotonin agonists: studies with microdialysis.

21 January 2018

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The substituted amphetamines 3,4-methylenedioxymethamphetamine, methamphetamine, p-chloroamphetamine and fenfluramine induce 5-hydroxytryptamine release via a common mechanism blocked by fluoxetine and cocaine

21 January 2018

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A comparison of the effects of 1-benzylpiperazine and dexamphetamine on human performance tests.

21 January 2018

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Piperazine-like compounds: a new group of designer drugs-of-abuse on the European market

21 January 2018

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Biochemical and electrophysiological evidence that RO 60-0175 inhibits mesolimbic dopaminergic function through serotonin(2C) receptors

21 January 2018

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Effects of mCPP on the extracellular concentrations of serotonin and dopamine in rat brain.

21 January 2018

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Hyperlocomotive and discriminative stimulus effects of cocaine are under the control of serotonin(2C) (5-HT(2C)) receptors in rat prefrontal cortex

21 January 2018

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Multiple 5-HT receptors are involved in the effects of acute MDMA treatment: studies on locomotor activity and responding for conditioned reinforcement

21 January 2018

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Acute effects of 3,4-methylenedioxymethamphetamine (MDMA) on monoamines in rat caudate

21 January 2018

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The pharmacology and clinical pharmacology of 3,4-methylenedioxymethamphetamine (MDMA, "ecstasy").

21 January 2018

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Functional correlates of serotonin 5-HT1 recognition sites

21 January 2018

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Effects of the enantiomers of MDA, MDMA and related analogues on [3H]serotonin and [3H]dopamine release from superfused rat brain slices

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Stimulus properties of antidepressants in the rat.

21 January 2018

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Effects of the selective 5-HT2A receptor antagonist MDL 100,907 on MDMA-induced locomotor stimulation in rats

21 January 2018

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Selective 6OHDA-induced destruction of mesolimbic dopamine neurons: abolition of psychostimulant-induced locomotor activity in rats

21 January 2018

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5-HT2A receptor stimulation by DOI, a 5-HT2A/2C receptor agonist, potentiates amphetamine-induced dopamine release in rat medial prefrontal cortex and nucleus accumbens

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MDMA: A Review of Epidemiological Data

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Which neuroreceptors mediate the subjective effects of MDMA in humans? A summary of mechanistic studies.

21 January 2018

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Chemistry, Pharmacology, Toxicology, and Hepatic Metabolism of Designer Drugs of the Amphetamine (Ecstasy), Piperazine, and Pyrrolidinophenone Types

21 January 2018

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3,4-Methylenedioxyamphetamine (MDA) analogues exhibit differential effects on synaptosomal release of 3H-dopamine and 3H-5-hydroxytryptamine

21 January 2018

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The pharmacology of the acute hyperthermic response that follows administration of 3,4-methylenedioxymethamphetamine (MDMA, 'ecstasy') to rats

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Ecstasy (MDMA): a review of its possible persistent psychological effects

21 January 2018

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Reversal of amphetamine-induced behaviours by MDL 100,907, a selective 5-HT2A antagonist.

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Effects of certain hallucinogenic amphetamine analogues on the release of [3H]serotonin from rat brain synaptosomes.

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5-HT2 receptor antagonism reduces hyperactivity induced by amphetamine, cocaine, and MK-801 but not D1 agonist C-APB

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Recreational Ecstasy/MDMA, the serotonin syndrome, and serotonergic neurotoxicity

21 January 2018

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Perfusate serotonin increases extracellular dopamine in the nucleus accumbens as measured by in vivo microdialysis.

21 January 2018

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Serotonin-releasing effects of substituted piperazines in vitro

21 January 2018

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5-HT2A and 5-HT2C/2B receptor subtypes modulate dopamine release induced in vivo by amphetamine and morphine in both the rat nucleus accumbens and striatum.

21 January 2018

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Reinforcing effects of MDMA ("ecstasy") in drug-naive and cocaine-trained rats

21 January 2018

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Therapeutic and adverse actions of serotonin transporter substrates

21 January 2018

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Amphetamine-type central nervous system stimulants release norepinephrine more potently than they release dopamine and serotonin

21 January 2018

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Development, maintenance and temporal pattern of self-administration maintained by ecstasy (MDMA) in rats

21 January 2018

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Mazindol attenuates the 3,4-methylenedioxymethamphetamine-induced formation of hydroxyl radicals and long-term depletion of serotonin in the striatum.

21 January 2018

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Interaction of arylpiperazines with 5-HT1A, 5-HT1B, 5-HT1C and 5-HT1D receptors: do discriminatory 5-HT1B receptor ligands exist?

21 January 2018

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Psychological and Cardiovascular Effects and Short-Term Sequelae of MDMA (“Ecstasy”) in MDMA-Naïve Healthy Volunteers

21 January 2018

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A2 (N-benzylpiperazine) a new drug of abuse in Sweden

21 January 2018

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The acute effects of methylenedioxymethamphetamine on dopamine release in the awake-behaving rat.

21 January 2018

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Intravenous administration of the serotonin agonist m-chlorophenylpiperazine (mCPP) increases extracellular serotonin in the diencephalon of awake rats

21 January 2018

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7 January 2021

Effector pathway-dependent relative efficacy at serotonin type 2A and 2C receptors: evidence for agonist-directed trafficking of receptor stimulus

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7 January 2021

Carrier-mediated release of serotonin by 3,4-methylenedioxymethamphetamine: implications for serotonin-dopamine interactions.

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7 January 2021

Methylenedioxymethamphetamine (MDMA, Ecstasy) neurotoxicity: cellular and molecular mechanisms

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7 January 2021

In vitro and in vivo neurochemical effects of methylenedioxymethamphetamine on striatal monoaminergic systems in the rat brain

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7 January 2021

Acute and subchronic effects of methylenedioxymethamphetamine [(+/-)MDMA] on locomotion and serotonin syndrome behavior in the rat

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7 January 2021

Identifiers

DOI

10.1038/SJ.NPP.1300585

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Dimensions Publication ID

1 August 2017

1018441766

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1 reference