(Q34361675)

1 August 2017

title

Nck-mediated recruitment of BCAP to the BCR regulates the PI(3)K-Akt pathway in B cells (English)

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1 August 2017

Angelo Castello

1

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1 August 2017

Mauro Gaya

2

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1 August 2017

Johannes Tucholski

3

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1 August 2017

Thomas Oellerich

4

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1 August 2017

Kun-Hui Lu

5

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1 August 2017

Anna Tafuri

6

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1 August 2017

Tony Pawson

7

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1 August 2017

Jürgen Wienands

8

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1 August 2017

Michael Engelke

9

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1 August 2017

Facundo D Batista

10

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1 August 2017

language of work or name

English

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publication date

4 August 2013

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1 August 2017

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1 August 2017

volume

14

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1 August 2017

issue

9

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1 August 2017

page(s)

966-975

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Anti-immunoglobulin stimulation of B lymphocytes activates src-related protein-tyrosine kinases

1 August 2017

cites work

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Identification of Nck family genes, chromosomal localization, expression, and signaling specificity

21 January 2018

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The Wiskott-Aldrich syndrome protein-interacting protein (WIP) binds to the adaptor protein Nck

21 January 2018

1 reference

Wiskott-Aldrich syndrome protein physically associates with Nck through Src homology 3 domains

21 January 2018

1 reference

Dynamic molecular interactions linking the T cell antigen receptor to the actin cytoskeleton.

21 January 2018

1 reference

Recruitment of Nck by CD3 epsilon reveals a ligand-induced conformational change essential for T cell receptor signaling and synapse formation

21 January 2018

1 reference

Fine tuning of the threshold of T cell selection by the Nck adapters.

21 January 2018

1 reference

Nck adaptors are positive regulators of the size and sensitivity of the T-cell repertoire

21 January 2018

1 reference

BLNK: a central linker protein in B cell activation

21 January 2018

1 reference

The B-cell antigen receptor signals through a preformed transducer module of SLP65 and CIN85

21 January 2018

1 reference

Drosophila photoreceptor axon guidance and targeting requires the dreadlocks SH2/SH3 adapter protein.

21 January 2018

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Phospholipase C-gamma2 and Vav cooperate within signaling microclusters to propagate B cell spreading in response to membrane-bound antigen

21 January 2018

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B cell ligand discrimination through a spreading and contraction response.

21 January 2018

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BLNK required for coupling Syk to PLC gamma 2 and Rac1-JNK in B cells

21 January 2018

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BLNK: molecular scaffolding through 'cis'-mediated organization of signaling proteins

21 January 2018

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Signal transduction by the B cell antigen receptor and its coreceptors

21 January 2018

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Association of SLP-65/BLNK with the B cell antigen receptor through a non-ITAM tyrosine of Ig-alpha

21 January 2018

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The direct recruitment of BLNK to immunoglobulin alpha couples the B-cell antigen receptor to distal signaling pathways

21 January 2018

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Receptor-facilitated antigen presentation requires the recruitment of B cell linker protein to Igalpha

21 January 2018

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The murine Nck SH2/SH3 adaptors are important for the development of mesoderm-derived embryonic structures and for regulating the cellular actin network

21 January 2018

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Nck adaptor proteins link nephrin to the actin cytoskeleton of kidney podocytes

21 January 2018

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Testing gene function early in the B cell lineage in mb1-cre mice

21 January 2018

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Resolution and characterization of pro-B and pre-pro-B cell stages in normal mouse bone marrow

21 January 2018

1 reference

21 January 2018

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Essential immunoregulatory role for BCAP in B cell development and function

21 January 2018

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Regulation of B-cell development by BCAP and CD19 through their binding to phosphoinositide 3-kinase

21 January 2018

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The phosphotyrosine peptide binding specificity of Nck1 and Nck2 Src homology 2 domains.

21 January 2018

1 reference

The B cell receptor promotes B cell activation and proliferation through a non-ITAM tyrosine in the Igalpha cytoplasmic domain

21 January 2018

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Regulation of class-switch recombination and plasma cell differentiation by phosphatidylinositol 3-kinase signaling

21 January 2018

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PI3 kinase signals BCR-dependent mature B cell survival

21 January 2018

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Optimal B-cell proliferation requires phosphoinositide 3-kinase-dependent inactivation of FOXO transcription factors

21 January 2018

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B cell receptor signaling down-regulates forkhead box transcription factor class O 1 mRNA expression via phosphatidylinositol 3-kinase and Bruton's tyrosine kinase.

21 January 2018

1 reference

Distinct functions for the transcription factor Foxo1 at various stages of B cell differentiation

21 January 2018

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Critical roles of Pten in B cell homeostasis and immunoglobulin class switch recombination.

21 January 2018

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LFA-1/ICAM-1 interaction lowers the threshold of B cell activation by facilitating B cell adhesion and synapse formation

21 January 2018

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Grb2 and the non-T cell activation linker NTAL constitute a Ca(2+)-regulating signal circuit in B lymphocytes

21 January 2018

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Subcellular localization of Grb2 by the adaptor protein Dok-3 restricts the intensity of Ca2+ signaling in B cells

21 January 2018

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Grb2 and Nck act cooperatively to promote actin-based motility of vaccinia virus

21 January 2018

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WIP provides an essential link between Nck and N-WASP during Arp2/3-dependent actin polymerization

21 January 2018

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CD169(+) macrophages present lipid antigens to mediate early activation of iNKT cells in lymph nodes

21 January 2018

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Dual phosphoproteomics and chemical proteomics analysis of erlotinib and gefitinib interference in acute myeloid leukemia cells

21 January 2018

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Defective TCR expression in transgenic mice constructed using cDNA-based α- and β-chain genes under the control of heterologous regulatory elements

21 January 2018

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B cell receptor-mediated uptake of CD1d-restricted antigen augments antibody responses by recruiting invariant NKT cell help in vivo

21 January 2018

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B cells acquire particulate antigen in a macrophage-rich area at the boundary between the follicle and the subcapsular sinus of the lymph node

21 January 2018

1 reference

12 December 2020

BCR-mediated uptake of antigen linked to TLR9 ligand stimulates B-cell proliferation and antigen-specific plasma cell formation

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12 December 2020

Association of the 72-kDa protein-tyrosine kinase PTK72 with the B cell antigen receptor

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12 December 2020

BCAP: the tyrosine kinase substrate that connects B cell receptor to phosphoinositide 3-kinase activation

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12 December 2020

B lymphocyte activation is accompanied by phosphorylation of a 72-kDa protein-tyrosine kinase

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12 December 2020

Tyrosine kinases Lyn and Syk regulate B cell receptor-coupled Ca2+ mobilization through distinct pathways

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12 December 2020

Identifiers

DOI

10.1038/NI.2685

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1 August 2017

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