(Q34368600)

1 August 2017

title

Azidothymidine: crystal structure and possible functional role of the azido group (English)

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1 August 2017

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A Camerman

1

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1 August 2017

D Mastropaolo

series ordinal

2

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1 August 2017

N Camerman

series ordinal

3

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1 August 2017

language of work or name

English

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publication date

1 December 1987

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1 August 2017

number of pages

4

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Proceedings of the National Academy of Sciences of the United States of America

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published in

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1 August 2017

volume

84

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1 August 2017

issue

23

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1 August 2017

page(s)

8239-8242

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Both 2',3'-dideoxythymidine and its 2',3'-unsaturated derivative (2',3'-dideoxythymidinene) are potent and selective inhibitors of human immunodeficiency virus replication in vitro.

1 August 2017

cites work

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=299517

Administration of 3'-azido-3'-deoxythymidine, an inhibitor of HTLV-III/LAV replication, to patients with AIDS or AIDS-related complex

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=299517

Phosphorylation of 3'-azido-3'-deoxythymidine and selective interaction of the 5'-triphosphate with human immunodeficiency virus reverse transcriptase

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=299517

3'-Azido-3'-deoxythymidine (BW A509U): an antiviral agent that inhibits the infectivity and cytopathic effect of human T-lymphotropic virus type III/lymphadenopathy-associated virus in vitro

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=299517

Inhibition of reverse transcriptase activity by 2',3'-dideoxythymidine 5'-triphosphate and its derivatives modified on the 3' position

6 July 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/2446321

12 December 2020

inferred from PubMed ID database lookup

Imminent marketing of AZT raises problems

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/2446321

12 December 2020

inferred from PubMed ID database lookup

Molecular structure of a deoxyribose-dinucleotide, sodium thymidylyl-(5' yields to 3')-thymidylate-(5') hydrate (pTpT), and a possible structural model for polythymidylate

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/2446321

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1073/PNAS.84.23.8239

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1 August 2017

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1 August 2017

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