(Q34370833)

1 August 2017

1 reference

title

Allosteric phenomena in cytochrome P450-catalyzed monooxygenations (English)

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1 August 2017

P Hlavica

1

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1 August 2017

D F Lewis

series ordinal

2

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1 August 2017

language of work or name

English

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publication date

1 September 2001

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1 August 2017

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1 August 2017

volume

268

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1 August 2017

issue

18

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1 August 2017

page(s)

4817-4832

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Structure of a cytochrome P450-redox partner electron-transfer complex

1 August 2017

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1 reference

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21 January 2018

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21 January 2018

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Sigmoidal kinetic model for two co-operative substrate-binding sites in a cytochrome P450 3A4 active site: an example of the metabolism of diazepam and its derivatives

21 January 2018

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Cooperativity in oxidations catalyzed by cytochrome P450 3A4.

21 January 2018

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Analysis of four residues within substrate recognition site 4 of human cytochrome P450 3A4: role in steroid hydroxylase activity and alpha-naphthoflavone stimulation.

21 January 2018

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Purification to homogeneity and enzymological characterization of a functional covalent complex composed of cytochromes P-450 isozyme 2 and b5 from rabbit liver

21 January 2018

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Evidence for lipid involvement in the high-affinity interaction between cimetidine and rat liver cytochrome P-450.

21 January 2018

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Substrates of human hepatic cytochrome P450 3A4.

21 January 2018

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The human CYP3A subfamily: practical considerations

21 January 2018

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Identification of three key residues in substrate recognition site 5 of human cytochrome P450 3A4 by cassette and site-directed mutagenesis.

21 January 2018

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Analysis of human cytochrome P450 3A4 cooperativity: construction and characterization of a site-directed mutant that displays hyperbolic steroid hydroxylation kinetics

21 January 2018

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Coexpression of genetically engineered fused enzyme between yeast NADPH-P450 reductase and human cytochrome P450 3A4 and human cytochrome b5 in yeast

21 January 2018

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In vitro assessment of human cytochrome P450.

21 January 2018

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Kinetic characterization and identification of the enzymes responsible for the hepatic biotransformation of adinazolam and N-desmethyladinazolam in man

21 January 2018

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Oxidation of aflatoxin B1 by bacterial recombinant human cytochrome P450 enzymes

21 January 2018

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Two catalytically distinct subforms of cytochrome P-450 3b as obtained from inbred rabbits.

21 January 2018

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An A245T mutation conveys on cytochrome P450eryF the ability to oxidize alternative substrates

21 January 2018

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Activation of CYP3A4: evidence for the simultaneous binding of two substrates in a cytochrome P450 active site.

21 January 2018

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Identification of the binding site on cytochrome P450 2B4 for cytochrome b5 and cytochrome P450 reductase.

21 January 2018

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Identification of key residues in rabbit liver microsomal cytochrome P450 2B4: importance in interactions with NADPH-cytochrome P450 reductase.

21 January 2018

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Residue 285 in cytochrome P450 2B4 lacking the NH(2)-terminal hydrophobic sequence has a role in the functional association of NADPH-cytochrome P450 reductase.

21 January 2018

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The kinetic and spectral characterization of the E. coli-expressed mammalian CYP4A7: cytochrome b5 effects vary with substrate

21 January 2018

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Conformational change and activation of cytochrome P450 2B1 induced by salt and phospholipid.

21 January 2018

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Rapid conformational changes of cytochrome P -450: Effect of dimyristoyl lecithin

21 January 2018

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Conformational change of cytochrome P-450 indicated by the measurement of fluorescence-energy transfer.

21 January 2018

1 reference

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Conformation between the substrate-binding site and heme of cytochrome P-450 studied by excitation energy transfer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2001.02412.X

The effect of dilauroyl-L-3-phosphatidylcholine on the interaction between cytochrome P-450 1A1 and benzo[a]pyrene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2001.02412.X

Effect of substrate on the spin state of cytochrome P-450 in hepatic microsomes

21 January 2018

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https://api.crossref.org/works/10.1046%2FJ.1432-1327.2001.02412.X

Coupling of spin, substrate, and redox equilibriums in cytochrome P450

21 January 2018

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CO binding kinetics of human cytochrome P450 3A4. Specific interaction of substrates with kinetically distinguishable conformers.

21 January 2018

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Circular dichroism studies on the binding of Type I substrates and reverse Type I compounds to rabbit liver microsomal cytochrome P-450

21 January 2018

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Temperature jump relaxation kinetics of the P-450cam spin equilibrium.

21 January 2018

1 reference

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Rabbit liver cytochrome P-450 2B5: high-level expression of the full-length protein in Escherichia coli, purification, and catalytic activity

21 January 2018

1 reference

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Steady-state and picosecond-time-resolved fluorescence studies on the recombinant heme domain of Bacillus megaterium cytochrome P-450.

21 January 2018

1 reference

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Kinetics of cytochrome P-450 reduction: evidence for faster reduction of the high-spin ferric state

21 January 2018

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Reduction kinetics of purified rat liver cytochrome P-450. Evidence for a sequential reaction mechanism dependent on the hemoprotein spin state.

21 January 2018

1 reference

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Spin state control of cytochrome P-450 reduction and catalytic activity in a reconstituted P-450 LM2 system as induced by a series of benzphetamine analogues.

21 January 2018

1 reference

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Differences in the spectral interactions between NADPH-cytochrome P-450 reductase and a series of cytochrome P-450 enzymes.

21 January 2018

1 reference

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Relationship between the rate of reductase-cytochrome P450 complex formation and the rate of first electron transfer

21 January 2018

1 reference

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Modification of cytochrome P-450 with fluorescein isothiocyanate.

21 January 2018

1 reference

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Influence of mutation of the amino-terminal signal anchor sequence of cytochrome P450 2B4 on the enzyme structure and electron transfer processes

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2001.02412.X

Quantitation of interaction between cytochrome P-450scc and adrenodoxin--analysis in the median UV-region by second derivative spectroscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2001.02412.X

A thermodynamic model of regulation: modulation of redox equilibria in camphor monoxygenase

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2001.02412.X

Spin state control of the hepatic cytochrome P450 redox potential

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2001.02412.X

High-pressure-induced transitions in microsomal cytochrome P450 2B4 in solution: evidence for conformational inhomogeneity in the oligomers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2001.02412.X

Stabilization of P450 2B4 by its association with P450 1A2 revealed by high-pressure spectroscopy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2001.02412.X

Interactions among P450 enzymes when combined in reconstituted systems: formation of a 2B4-1A2 complex with a high affinity for NADPH-cytochrome P450 reductase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2001.02412.X

Reconstitution of recombinant cytochrome P450 2C10(2C9) and comparison with cytochrome P450 3A4 and other forms: effects of cytochrome P450-P450 and cytochrome P450-b5 interactions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2001.02412.X

Roles of divalent metal ions in oxidations catalyzed by recombinant cytochrome P450 3A4 and replacement of NADPH--cytochrome P450 reductase with other flavoproteins, ferredoxin, and oxygen surrogates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2001.02412.X

Lack of electron transfer from cytochrome b5 in stimulation of catalytic activities of cytochrome P450 3A4. Characterization of a reconstituted cytochrome P450 3A4/NADPH-cytochrome P450 reductase system and studies with apo-cytochrome b5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2001.02412.X

Interactions between redox partners in various cytochrome P450 systems: functional and structural aspects

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2001.02412.X

Cytochrome b5 augments the 17,20-lyase activity of human P450c17 without direct electron transfer

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2001.02412.X

Hydrodynamic characterization of highly purified and functionally active liver microsomal cytochrome P-450

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2001.02412.X

Lipid binding to the amphipathic membrane protein cytochrome b5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2001.02412.X

Cytochrome P-450 spin state and leakiness of the monooxygenase pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2001.02412.X

Spectral intermediates in the reaction of oxygen with purified liver microsomal cytochrome P-450

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2001.02412.X

P450cam: oxygenated complexes stabilized at low temperature

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2001.02412.X

Substrate analogue induced changes of the CO-stretching mode in the cytochrome P450cam-carbon monoxide complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2001.02412.X

Control of androgen biosynthesis in the human through the interaction of Arg347 and Arg358 of CYP17 with cytochrome b5

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2001.02412.X

CO binding studies of engineered cytochrome P-450ds: effects of mutations at putative distal sites in the presence of polycyclic hydrocarbons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2001.02412.X

Crystal structures of metyrapone- and phenylimidazole-inhibited complexes of cytochrome P-450cam

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2001.02412.X

P450 superfamily: update on new sequences, gene mapping, accession numbers and nomenclature.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2001.02412.X

1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine as a Substrate of Cytochrome P450 2D6: Allosteric Effects of NADPH−Cytochrome P450 Reductase†

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2001.02412.X

Roles of Cytochrome b5in the Oxidation of Testosterone and Nifedipine by Recombinant Cytochrome P450 3A4 and by Human Liver Microsomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2001.02412.X

10.1046/J.1432-1327.2001.02412.X

21 January 2018

Identifiers

DOI

1 reference

1 August 2017

1 reference