(Q34378928)

1 August 2017

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title

Implications and consequences of enzyme induction on preclinical and clinical drug development (English)

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1 August 2017

Worboys PD

1

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1 August 2017

Carlile DJ

series ordinal

2

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1 August 2017

language of work or name

English

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publication date

1 August 2001

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1 August 2017

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1 August 2017

volume

31

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1 August 2017

issue

8-9

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1 August 2017

page(s)

539-556

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The relationship among microsomal enzyme induction, liver weight and histological change in rat toxicology studies

1 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1080%2F00498250110054623

Effect of omeprazole treatment on diazepam plasma levels in slow versus normal rapid metabolizers of omeprazole.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250110054623

Induction of cytochrome P-450 in cultured rat hepatocytes. The heterogeneous localization of specific isoenzymes using immunocytochemistry

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250110054623

Pharmacokinetic interactions with felbamate. In vitro-in vivo correlation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250110054623

Analysis of Human Cytochrome P450 Catalytic Activities and Expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250110054623

Integration of in vitro data into allometric scaling to predict hepatic metabolic clearance in man: application to 10 extensively metabolized drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250110054623

Present status of the application of cryopreserved hepatocytes in the evaluation of xenobiotics: consensus of an international expert panel

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250110054623

Expression and induction of CYP1A1/1A2, CYP2A6 and CYP3A4 in primary cultures of human hepatocytes: a 10-year follow-up

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250110054623

Enzyme induction in the cytochrome P-450 system

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250110054623

The maintenance of cytochrome P-450 in rat hepatocyte culture: some applications of liver cell cultures to the study of drug metabolism, toxicity and the induction of the P-450 system

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250110054623

Hepatic clearance of drugs. I. Theoretical considerations of a "well-stirred" model and a "parallel tube" model. Influence of hepatic blood flow, plasma and blood cell binding, and the hepatocellular enzymatic activity on hepatic drug clearance

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250110054623

Relevance of induction of human drug-metabolizing enzymes: pharmacological and toxicological implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250110054623

Antiepileptic drugs. A review of clinically significant drug interactions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250110054623

Use of precision-cut rat liver slices for studies of xenobiotic metabolism and toxicity: comparison of the Krumdieck and Brendel tissue slicers

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250110054623

Rifampin and Warfarin: A Drug Interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250110054623

Selective expression of cytochrome P450 CYP3A mRNAs in embryonic and adult human liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250110054623

Induction and drug development

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250110054623

The application of DNA microarrays in gene expression analysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250110054623

Hepatocyte isolation stimulates formation of interferon stimulatory response element DNA-protein complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250110054623

The effect of dexamethasone on the pharmacokinetics of triazolam.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250110054623

Biomedical discovery with DNA arrays

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250110054623

Prediction of hepatic clearance from microsomes, hepatocytes, and liver slices

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250110054623

Effects of lansoprazole on pharmacokinetics and metabolism of theophylline

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250110054623

Effect of troglitazone on the pharmacokinetics of an oral contraceptive agent

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250110054623

A pharmacokinetic interaction between carbamazepine and olanzapine: observations on possible mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250110054623

Alteration of transcription factor mRNAs during the isolation and culture of rat hepatocytes suggests the activation of a proliferative mode underlies their de-differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250110054623

Influence of phenobarbital treatment on cimetidine kinetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250110054623

Use of human hepatocytes to study P450 gene induction

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250110054623

Induction of rat hepatic glucocorticoid-inducible cytochrome P450 3A by metyrapone

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250110054623

In vitro permeability across Caco-2 cells (colonic) can predict in vivo (small intestinal) absorption in man--fact or myth

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250110054623

10.1080/00498250110054623

21 January 2018

Identifiers

DOI

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1 August 2017

1 reference