(Q34381905)

1 August 2017

title

Structure of the IRS-1 PTB domain bound to the juxtamembrane region of the insulin receptor (English)

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1 August 2017

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M J Eck

1

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1 August 2017

S Dhe-Paganon

2

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1 August 2017

T Trüb

3

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1 August 2017

R T Nolte

4

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1 August 2017

S E Shoelson

5

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1 August 2017

language of work or name

English

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publication date

1 May 1996

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1 August 2017

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1 August 2017

volume

85

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1 August 2017

issue

5

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1 August 2017

page(s)

695-705

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Human Skeletal Muscle Insulin Receptor Substrate-1: Characterization of the cDNA, Gene, and Chromosomal Localization

1 August 2017

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A phosphotyrosine interaction domain

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Shc Binding to Nerve Growth Factor Receptor Is Mediated by the Phosphotyrosine Interaction Domain

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Recognition of a high-affinity phosphotyrosyl peptide by the Src homology-2 domain of p56lck

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Structure of the regulatory domains of the Src-family tyrosine kinase Lck

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Spatial constraints on the recognition of phosphoproteins by the tandem SH2 domains of the phosphatase SH-PTP2

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7 January 2021

Crystal structure at 2.2 A resolution of the pleckstrin homology domain from human dynamin

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7 January 2021

Structure of the high affinity complex of inositol trisphosphate with a phospholipase C pleckstrin homology domain

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7 January 2021

The regions of the Fe65 protein homologous to the phosphotyrosine interaction/phosphotyrosine binding domain of Shc bind the intracellular domain of the Alzheimer's amyloid precursor protein

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7 January 2021

Phosphotyrosine-dependent interaction of SHC and insulin receptor substrate 1 with the NPEY motif of the insulin receptor via a novel non-SH2 domain

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Molecular basis for interaction of the protein tyrosine kinase ZAP-70 with the T-cell receptor

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Distinct modes of interaction of SHC and insulin receptor substrate-1 with the insulin receptor NPEY region via non-SH2 domains

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7 January 2021

Interaction of insulin receptor substrate-2 (IRS-2) with the insulin and insulin-like growth factor I receptors. Evidence for two distinct phosphotyrosine-dependent interaction domains within IRS-2

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7 January 2021

Crystal structure of the tyrosine kinase domain of the human insulin receptor

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7 January 2021

Structure of the binding site for inositol phosphates in a PH domain

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7 January 2021

An alternative to SH2 domains for binding tyrosine-phosphorylated proteins

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7 January 2021

PTB domain binding to signaling proteins through a sequence motif containing phosphotyrosine

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7 January 2021

Crystal structures of peptide complexes of the amino-terminal SH2 domain of the Syp tyrosine phosphatase

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7 January 2021

The PH domain: a common piece in the structural patchwork of signalling proteins

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7 January 2021

The pleckstrin homology domain in insulin receptor substrate-1 sensitizes insulin signaling

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Protein folding and association: insights from the interfacial and thermodynamic properties of hydrocarbons

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Crystal structure of the PI 3-kinase p85 amino-terminal SH2 domain and its phosphopeptide complexes

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7 January 2021

Characterization of an interaction between insulin receptor substrate 1 and the insulin receptor by using the two-hybrid system

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7 January 2021

Phosphatidylinositol 3-kinase p85 SH2 domain specificity defined by direct phosphopeptide/SH2 domain binding

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7 January 2021

Insulin receptor substrate-2 binds to the insulin receptor through its phosphotyrosine-binding domain and through a newly identified domain comprising amino acids 591-786

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7 January 2021

Structure of the insulin receptor substrate IRS-1 defines a unique signal transduction protein

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7 January 2021

Pleiotropic insulin signals are engaged by multisite phosphorylation of IRS-1

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7 January 2021

Role of IRS-2 in insulin and cytokine signalling

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7 January 2021

Specificity of the PTB domain of Shc for beta turn-forming pentapeptide motifs amino-terminal to phosphotyrosine

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7 January 2021

A conserved amino-terminal Shc domain binds to phosphotyrosine motifs in activated receptors and phosphopeptides

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7 January 2021

Tyrosine phosphorylation of insulin receptor substrate-1 in vivo depends upon the presence of its pleckstrin homology region

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7 January 2021

Crystal structure of the phosphotyrosine recognition domain SH2 of v-src complexed with tyrosine-phosphorylated peptides

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7 January 2021

Binding of a high affinity phosphotyrosyl peptide to the Src SH2 domain: crystal structures of the complexed and peptide-free forms

1 reference

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7 January 2021

Mutation of the insulin receptor at tyrosine 960 inhibits signal transmission but does not affect its tyrosine kinase activity

1 reference

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7 January 2021

PTB domains of IRS-1 and Shc have distinct but overlapping binding specificities

1 reference

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7 January 2021

Structural basis for IL-4 receptor phosphopeptide recognition by the IRS-1 PTB domain

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7 January 2021

Evaluation of single-crystal X-ray diffraction data from a position-sensitive detector

1 reference

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7 January 2021

10.1016/S0092-8674(00)81236-2

Identifiers

DOI

1 reference

1 August 2017

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