(Q34383220)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11574931%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

review article

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title

A comparison of normal and leukemic stem cell biology in Chronic Myeloid Leukemia (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11574931%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

main subject

chronic myeloid leukemia

0 references

1 reference

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1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11574931%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

Tessa Holyoake

series ordinal

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11574931%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

author name string

Jørgensen HG

series ordinal

1

1 reference

1 August 2017

Holyoake TL

series ordinal

2

1 reference

1 August 2017

publication date

1 September 2001

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11574931%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

published in

Hematological Oncology

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11574931%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

volume

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11574931%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11574931%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

page(s)

89-106

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11574931%20AND%20SRC:MED&resulttype=core&format=json

Philadelphia chromosomal breakpoints are clustered within a limited region, bcr, on chromosome 22

11 November 2019

cites work

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21 January 2018

Chronic myeloid leukemia

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Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells

21 January 2018

1 reference

Telomere length dynamics in human lymphocyte subpopulations measured by flow cytometry.

21 January 2018

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Structure and function of telomeres

21 January 2018

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Asymmetric cell divisions sustain long-term hematopoiesis from single-sorted human fetal liver cells

21 January 2018

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Telomere shortening and tumor formation by mouse cells lacking telomerase RNA

21 January 2018

1 reference

Essential role of mouse telomerase in highly proliferative organs

21 January 2018

1 reference

Extension of life-span by introduction of telomerase into normal human cells

21 January 2018

1 reference

21 January 2018

1 reference

Telomere fluorescence measurements in granulocytes and T lymphocyte subsets point to a high turnover of hematopoietic stem cells and memory T cells in early childhood.

21 January 2018

1 reference

Accelerated telomere shortening in young recipients of allogeneic bone-marrow transplants.

21 January 2018

1 reference

In vivo telomere dynamics of human hematopoietic stem cells

21 January 2018

1 reference

Acute leukaemia in bcr/abl transgenic mice

21 January 2018

1 reference

The P190, P210, and P230 forms of the BCR/ABL oncogene induce a similar chronic myeloid leukemia-like syndrome in mice but have different lymphoid leukemogenic activity

21 January 2018

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Abl tyrosine protein kinase

21 January 2018

1 reference

Induction of apoptosis by a dominant negative H-RAS mutant (116Y) in K562 cells

21 January 2018

1 reference

Activation of hematopoietic growth factor signal transduction pathways by the human oncogene BCR/ABL.

21 January 2018

1 reference

BCR-ABL accelerates C2-ceramide-induced apoptosis

21 January 2018

1 reference

Autocrine production and action of IL-3 and granulocyte colony-stimulating factor in chronic myeloid leukemia.

21 January 2018

1 reference

High-resolution cell division tracking demonstrates the FLt3-ligand-dependence of human marrow CD34+CD38- cell production in vitro

21 January 2018

1 reference

Telomerase activity and cytogenetic changes in chronic myeloid leukemia with disease progression.

21 January 2018

1 reference

Tyrosine protein kinase inhibition and cancer.

21 January 2018

1 reference

Fused transcript of abl and bcr genes in chronic myelogenous leukaemia

21 January 2018

1 reference

Letter: A new consistent chromosomal abnormality in chronic myelogenous leukaemia identified by quinacrine fluorescence and Giemsa staining

21 January 2018

1 reference

7 January 2021

Long-term marrow culture reveals chromosomally normal hematopoietic progenitor cells in patients with Philadelphia chromosome-positive chronic myelogenous leukemia

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7 January 2021

Hematologic remission and cytogenetic improvement induced by recombinant human interferon alpha A in chronic myelogenous leukemia

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7 January 2021

Intensive combination chemotherapy (ROAP 10) and splenectomy in the management of chronic myelogenous leukemia

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7 January 2021

Intensive chemotherapy induction followed by interferon-alpha maintenance in patients with Philadelphia chromosome-positive chronic myelogenous leukemia

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7 January 2021

In vivo eradication of human BCR/ABL-positive leukemia cells with an ABL kinase inhibitor

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7 January 2021

Lessons learned from the development of an abl tyrosine kinase inhibitor for chronic myelogenous leukemia

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7 January 2021

A direct measurement of the radiation sensitivity of normal mouse bone marrow cells

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7 January 2021

Identification of resting cells by dual-parameter flow cytometry of statin expression and DNA content.

1 reference

7 January 2021

Short telomeres on human chromosome 17p

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7 January 2021

Functional Failures of Cultured Human Diploid Fibroblasts After Continued Population Doublings

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7 January 2021

Human Cells and Aging

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7 January 2021

Evidence for a mitotic clock in human hematopoietic stem cells: loss of telomeric DNA with age.

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7 January 2021

Telomerase activity in normal and malignant hematopoietic cells

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7 January 2021

Differential expression of telomerase activity in hematopoietic progenitors from adult human bone marrow

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7 January 2021

Regulation of telomere length and telomerase in T and B cells: a mechanism for maintaining replicative potential

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7 January 2021

Telomerase activity in human cancer.

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7 January 2021

Reconstitution of telomerase activity in normal human cells leads to elongation of telomeres and extended replicative life span

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7 January 2021

Correlating telomerase activity levels with human neuroblastoma outcomes

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7 January 2021

Telomere shortening in leucocyte subsets of long-term survivors of allogeneic bone marrow transplantation

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7 January 2021

Telomere length changes in patients undergoing hematopoietic stem cell transplantation

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7 January 2021

Changes of telomere length in children after hematopoietic stem cell transplantation

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7 January 2021

bcr-abl, the hallmark of chronic myeloid leukaemia in man, induces multiple haemopoietic neoplasms in mice.

1 reference

7 January 2021

Induction of chronic myelogenous leukemia in mice by the P210bcr/abl gene of the Philadelphia chromosome

1 reference

7 January 2021

Interferon response in chronic myeloid leukaemia correlates with ABL/BCR expression: a preliminary study

1 reference

7 January 2021

Lack of correlation between ABL-BCR expression and response to interferon-alpha in chronic myeloid leukaemia

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7 January 2021

Mutant forms of growth factor-binding protein-2 reverse BCR-ABL-induced transformation

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7 January 2021

CRKL links p210BCR/ABL with paxillin in chronic myelogenous leukemia cells

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7 January 2021

Differences between normal and CML stem cells: potential targets for clinical exploitation

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7 January 2021

Retrovirus-mediated transfer and expression of the interleukin-3 gene in mouse hematopoietic cells result in a myeloproliferative disorder

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7 January 2021

Targeted in vivo infection with a retroviral vector carrying the interleukin-3 (multi-CSF) gene leads to immortalization and leukemic transformation of primitive hematopoietic progenitor cells

1 reference

7 January 2021

Flow cytometric estimation of DNA and RNA content in intact cells stained with hoechst 33342 and pyronin Y

1 reference

7 January 2021

Telomere length shortening is associated with disease evolution in chronic myelogenous leukemia.

1 reference

7 January 2021

The relationship between telomere length and therapy-associated cytogenetic responses in patients with chronic myeloid leukemia

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7 January 2021

Transformation of an interleukin 3-dependent hematopoietic cell line by the chronic myelogenous leukemia-specific P210bcr/abl protein

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7 January 2021

Apoptosis in chronic myeloid leukaemia: normal responses by progenitor cells to growth factor deprivation, X-irradiation and glucocorticoids

1 reference

7 January 2021

Mechanisms underlying abnormal trafficking of malignant progenitors in chronic myelogenous leukemia. Decreased adhesion to stroma and fibronectin but increased adhesion to the basement membrane components laminin and collagen type IV

1 reference

7 January 2021

Activation of beta1 integrins on CML progenitors reveals cooperation between beta1 integrins and CD44 in the regulation of adhesion and proliferation

1 reference

7 January 2021

BCR/ABL induces multiple abnormalities of cytoskeletal function

1 reference

7 January 2021

Interferon-alpha restores the deficient expression of the cytoadhesion molecule lymphocyte function antigen-3 by chronic myelogenous leukemia progenitor cells

1 reference

7 January 2021

Interferon-alpha restores normal adhesion of chronic myelogenous leukemia hematopoietic progenitors to bone marrow stroma by correcting impaired beta 1 integrin receptor function

1 reference

7 January 2021

Protein kinase inhibitors: probes for the functions of protein phosphorylation

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7 January 2021

Blocking of EGF-dependent cell proliferation by EGF receptor kinase inhibitors

1 reference

7 January 2021

Identifiers

DOI

10.1002/HON.667

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11574931%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

1 reference