(Q34386221)

1 August 2017

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title

Adenosylcobalamin-dependent isomerases: new insights into structure and mechanism (English)

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1 August 2017

E N Marsh

1

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1 August 2017

C L Drennan

series ordinal

2

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1 August 2017

publication date

1 October 2001

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Current Opinion in Chemical Biology

1 August 2017

published in

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1 August 2017

volume

5

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1 August 2017

issue

5

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1 August 2017

page(s)

499-505

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A radical approach to enzyme catalysis

1 August 2017

cites work

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7 January 2021

Structure-based perspectives on B12-dependent enzymes

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7 January 2021

The Yin-Yang of cobalamin biochemistry

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7 January 2021

Coenzyme B12 (cobalamin)-dependent enzymes

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7 January 2021

Adenosylcobalamin-dependent enzymes

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Radical mechanisms in adenosylmethionine- and adenosylcobalamin-dependent enzymatic reactions

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7 January 2021

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7 January 2021

Review Article Coenzyme-B(12)-Dependent Glutamate Mutase

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7 January 2021

Mechanisms of coenzyme B12-dependent rearrangements

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7 January 2021

Cobalamin-dependent methionine synthase: the structure of a methylcobalamin-binding fragment and implications for other B12-dependent enzymes

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7 January 2021

How coenzyme B12 radicals are generated: the crystal structure of methylmalonyl-coenzyme A mutase at 2 A resolution

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7 January 2021

Glutamate mutase from Clostridium cochlearium: the structure of a coenzyme B12-dependent enzyme provides new mechanistic insights

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7 January 2021

A new mode of B12 binding and the direct participation of a potassium ion in enzyme catalysis: X-ray structure of diol dehydratase

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7 January 2021

Binding of Cob(II)alamin to the adenosylcobalamin-dependent ribonucleotide reductase from Lactobacillus leichmannii. Identification of dimethylbenzimidazole as the axial ligand

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7 January 2021

Evidence that cobalt-carbon bond homolysis is coupled to hydrogen atom abstraction from substrate in methylmalonyl-CoA mutase

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7 January 2021

Coupling of cobalt-carbon bond homolysis and hydrogen atom abstraction in adenosylcobalamin-dependent glutamate mutase

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7 January 2021

Studies on the catalysis of carbon-cobalt bond homolysis by ribonucleoside triphosphate reductase: evidence for concerted carbon-cobalt bond homolysis and thiyl radical formation

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7 January 2021

Isotope effects in the transient phases of the reaction catalyzed by ethanolamine ammonia-lyase: determination of the number of exchangeable hydrogens in the enzyme-cofactor complex.

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7 January 2021

Use of isotope effects to elucidate enzyme mechanisms

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7 January 2021

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Thermodynamic and kinetic characterization of Co-C bond homolysis catalyzed by coenzyme B(12)-dependent methylmalonyl-CoA mutase

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7 January 2021

Thermodynamic and kinetic studies on carbon-cobalt bond homolysis by ribonucleoside triphosphate reductase: the importance of entropy in catalysis

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7 January 2021

Conformational changes on substrate binding to methylmalonyl CoA mutase and new insights into the free radical mechanism

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7 January 2021

How a protein generates a catalytic radical from coenzyme B(12): X-ray structure of a diol-dehydratase-adeninylpentylcobalamin complex

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7 January 2021

Understanding the Mechanism of B12-Dependent Methylmalonyl-CoA Mutase: Partial Proton Transfer in Action

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7 January 2021

Interconversion of (S)-glutamate and (2S,3S)-3-methylaspartate: a distinctive B(12)-dependent carbon-skeleton rearrangement

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7 January 2021

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7 January 2021

Proton transfer from histidine 244 may facilitate the 1,2 rearrangement reaction in coenzyme B(12)-dependent methylmalonyl-CoA mutase

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7 January 2021

Protection of radical intermediates at the active site of adenosylcobalamin-dependent methylmalonyl-CoA mutase

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7 January 2021

Rearrangement of L-2-hydroxyglutarate to L-threo-3-methylmalate catalyzed by adenosylcobalamin-dependent glutamate mutase

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7 January 2021

Identification of cis-ethanesemidione as the organic radical derived from glycolaldehyde in the suicide inactivation of dioldehydrase and of ethanolamine ammonia-lyase.

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7 January 2021

10.1016/S1367-5931(00)00238-6

Identifiers

DOI

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1 August 2017

1 reference