(Q34386843)

1 August 2017

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title

Peptide hormone binding to G-protein-coupled receptors: structural characterization via NMR techniques (English)

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G protein-coupled receptor

1 August 2017

main subject

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author name string

Mierke DF

series ordinal

1

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1 August 2017

Giragossian C

series ordinal

2

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1 August 2017

publication date

1 September 2001

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Medicinal Research Reviews

1 August 2017

published in

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1 August 2017

volume

21

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1 August 2017

issue

5

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1 August 2017

page(s)

450-471

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Expanding horizons for receptors coupled to G proteins: diversity and disease

1 August 2017

cites work

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GPCRDB: an information system for G protein-coupled receptors

21 January 2018

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The impact of genomics on drug discovery

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Structure-activity relationships of G protein-coupled receptors

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Analysis of membrane and surface protein sequences with the hydrophobic moment plot

21 January 2018

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A simple method for displaying the hydropathic character of a protein

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Model for the structure of bacteriorhodopsin based on high-resolution electron cryo-microscopy

21 January 2018

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X-ray structure of bacteriorhodopsin at 2.5 angstroms from microcrystals grown in lipidic cubic phases

21 January 2018

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Projection structure of frog rhodopsin in two crystal forms

21 January 2018

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An alpha-carbon template for the transmembrane helices in the rhodopsin family of G-protein-coupled receptors

21 January 2018

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Crystal structure of rhodopsin: A G protein-coupled receptor

21 January 2018

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WHAT IF: a molecular modeling and drug design program

21 January 2018

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The prediction and orientation of α-helices from sequence alignments: the combined use of environment-dependent substitution tables, Fourier transform methods and helix capping rules

21 January 2018

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Structure and function of G protein-coupled receptors

21 January 2018

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Conversion of antagonist-binding site to metal-ion site in the tachykinin NK-1 receptor.

21 January 2018

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Engineering of metal-ion sites as distance constraints in structural and functional analysis of 7TM receptors

21 January 2018

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Modeling of G-protein-coupled receptors: application to dopamine, adrenaline, serotonin, acetylcholine, and mammalian opsin receptors

21 January 2018

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Arrangement of transmembrane domains in adrenergic receptors. Similarity to bacteriorhodopsin

21 January 2018

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21 January 2018

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Structural features and light-dependent changes in the sequence 306-322 extending from helix VII to the palmitoylation sites in rhodopsin: a site-directed spin-labeling study

21 January 2018

1 reference

Agonist-induced conformational changes at the cytoplasmic side of transmembrane segment 6 in the beta 2 adrenergic receptor mapped by site-selective fluorescent labeling.

21 January 2018

1 reference

Mapping light-dependent structural changes in the cytoplasmic loop connecting helices C and D in rhodopsin: a site-directed spin labeling study.

21 January 2018

1 reference

Conformational characterization of a peptide mimetic of the third cytoplasmic loop of the G-protein coupled parathyroid hormone/parathyroid hormone related protein receptor

21 January 2018

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Binding domain of human parathyroid hormone receptor: from conformation to function

21 January 2018

1 reference

Molecular complex of cholecystokinin-8 and N-terminus of the cholecystokinin A receptor by NMR spectroscopy

21 January 2018

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Intermolecular interactions between cholecystokinin-8 and the third extracellular loop of the cholecystokinin A receptor

21 January 2018

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Molecular basis of muscarinic acetylcholine receptor function

21 January 2018

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How receptors talk to trimeric G proteins

21 January 2018

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G protein-coupled receptors in silico

21 January 2018

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Role of extracellular disulfide-bonded cysteines in the ligand binding function of the beta 2-adrenergic receptor

21 January 2018

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The peptide binding site of the substance P (NK-1) receptor localized by a photoreactive analogue of substance P: presence of a disulfide bond

21 January 2018

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Disulfide bridges in interleukin-8 probed using non-natural disulfide analogues: dissociation of roles in structure from function

21 January 2018

1 reference

Role of the extracellular regions of the parathyroid hormone (PTH)/PTH-related peptide receptor in hormone binding

21 January 2018

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Parathyroid hormone-receptor interactions identified directly by photocross-linking and molecular modeling studies

21 January 2018

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Motif mutation of bradykinin B2 receptor second intracellular loop and proximal C terminus is critical for signal transduction, internalization, and resensitization.

21 January 2018

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Molecular characterization of the receptor-ligand complex for parathyroid hormone.

21 January 2018

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Basic local alignment search tool

21 January 2018

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Gapped BLAST and PSI-BLAST: a new generation of protein database search programs

21 January 2018

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Molecular simulation of dynorphin A-(1-10) binding to extracellular loop 2 of the kappa-opioid receptor. A model for receptor activation

21 January 2018

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GROMACS: A message-passing parallel molecular dynamics implementation

21 January 2018

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Photoaffinity labeling of mutant neurokinin-1 receptors reveals additional structural features of the substance P/NK-1 receptor complex

21 January 2018

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Towards 3D structures of G protein-coupled receptors: a multidisciplinary approach

21 January 2018

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Structural basis of glutamate recognition by a dimeric metabotropic glutamate receptor

21 January 2018

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Crystal structure of the ectodomain of Methuselah, a Drosophila G protein-coupled receptor associated with extended lifespan

21 January 2018

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Path of the polypeptide in bacteriorhodopsin

21 January 2018

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Lipidic cubic phases: a novel concept for the crystallization of membrane proteins

21 January 2018

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Membrane protein crystallization in lipidic mesophases: detergent effects

21 January 2018

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A lipid's eye view of membrane protein crystallization in mesophases

21 January 2018

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Lipidic cubic phase crystallization of bacteriorhodopsin and cryotrapping of intermediates: towards resolving a revolving photocycle

21 January 2018

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Structural changes in bacteriorhodopsin during ion transport at 2 angstrom resolution

21 January 2018

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Coupling photoisomerization of retinal to directional transport in bacteriorhodopsin

21 January 2018

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High-resolution X-ray structure of an early intermediate in the bacteriorhodopsin photocycle

21 January 2018

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Helix deformation is coupled to vectorial proton transport in the photocycle of bacteriorhodopsin

21 January 2018

1 reference

Folding of peptide fragments comprising the complete sequence of proteins. Models for initiation of protein folding. I. Myohemerythrin

21 January 2018

1 reference

Contribution of increased length and intact capping sequences to the conformational preference for helix in a 31-residue peptide from the C terminus of myohemerythrin

21 January 2018

1 reference

Regulation of retinal transducin by C-terminal peptides of rhodopsin

21 January 2018

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C-terminal peptides of rhodopsin. Determination of the optimum sequence for recognition of retinal transducin

21 January 2018

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Three cytoplasmic loops of rhodopsin interact with transducin

21 January 2018

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Structure of the third cytoplasmic loop of bovine rhodopsin

21 January 2018

1 reference

Structure of the C-terminal fragment 300-320 of the rat angiotensin II AT1A receptor and its relevance with respect to G-protein coupling

21 January 2018

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Solution structure of the second extracellular loop of human thromboxane A2 receptor

21 January 2018

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NMR studies of peptides and proteins associated with membranes

21 January 2018

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Peptide structural analysis by solid-state NMR spectroscopy

21 January 2018

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Role of membrane lipids in peptide hormone function: binding of enkephalins to micelles

21 January 2018

1 reference

Backbone dynamics of a model membrane protein: 13C NMR spectroscopy of alanine methyl groups in detergent-solubilized M13 coat protein

21 January 2018

1 reference

Nuclear magnetic resonance investigation of the conformation of delta-haemolysin bound to dodecylphosphocholine micelles

21 January 2018

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NMR studies of adrenocorticotropin hormone peptides in sodium dodecylsulfate and dodecylphosphocholine micelles: proline isomerism and interactions of the peptides with micelles

21 January 2018

1 reference

Structures of the M2 channel-lining segments from nicotinic acetylcholine and NMDA receptors by NMR spectroscopy

21 January 2018

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Effects of glycosylation on the structure and dynamics of eel calcitonin in micelles and lipid bilayers determined by nuclear magnetic resonance spectroscopy

21 January 2018

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Structures of the intradiskal loops and amino terminus of the G-protein receptor, rhodopsin

21 January 2018

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Conformation of a beta-adrenoceptor-derived signal transducing peptide as inferred by circular dichroism and 1H NMR spectroscopy.

21 January 2018

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Membrane lipid phase as catalyst for peptide-receptor interactions

21 January 2018

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Peptide-membrane interactions and a new principle in quantitative structure-activity relationships

21 January 2018

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In search of the 'bio-active conformation'--is it induced by the target cell membrane?

21 January 2018

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New evidence for a membrane-bound pathway in hormone receptor binding

21 January 2018

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Conformation of a peptide ligand bound to its G-protein coupled receptor

21 January 2018

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The peripheral cholecystokinin receptors

21 January 2018

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21 January 2018

CCK receptor antagonists

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21 January 2018

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Gene structure of human cholecystokinin (CCK) type-A receptor: body fat content is related to CCK type-A receptor gene promoter polymorphism

21 January 2018

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Inhibitors of tripeptidyl peptidase II. 2. Generation of the first novel lead inhibitor of cholecystokinin-8-inactivating peptidase: a strategy for the design of peptidase inhibitors.

21 January 2018

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2,7-Dioxo-2,3,4,5,6,7-hexahydro-1H-benzo[h][1,4]diazonine as a new template for the design of CCK(2) receptor antagonists

21 January 2018

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Development of peptide 3D structure mimetics: rational design of novel peptoid cholecystokinin receptor antagonists

21 January 2018

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CCK peptides with combined features of hexa- and tetrapeptide CCK-A agonists

21 January 2018

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Synthesis and SAR of new 5-phenyl-3-ureido-1,5-benzodiazepines as cholecystokinin-B receptor antagonists

21 January 2018

1 reference

Identification of two amino acids of the human cholecystokinin-A receptor that interact with the N-terminal moiety of cholecystokinin.

21 January 2018

1 reference

Met-195 of the cholecystokinin-A receptor interacts with the sulfated tyrosine of cholecystokinin and is crucial for receptor transition to high affinity state

21 January 2018

1 reference

Arginine 336 and asparagine 333 of the human cholecystokinin-A receptor binding site interact with the penultimate aspartic acid and the C-terminal amide of cholecystokinin.

21 January 2018

1 reference

Direct identification of a distinct site of interaction between the carboxyl-terminal residue of cholecystokinin and the type A cholecystokinin receptor using photoaffinity labeling

21 January 2018

1 reference

1H NMR conformational study of sulfated and non-sulfated cholecystokinin fragment CCK27-33: influence of the sulfate group on the peptide folding

21 January 2018

1 reference

Conformational analysis of cholecystokinin CCK26-33 and related fragments by 1H NMR spectroscopy, fluorescence-transfer measurements, and calculations

21 January 2018

1 reference

Direct identification of the agonist binding site in the human brain cholecystokininB receptor

21 January 2018

1 reference

Arrangement of rhodopsin transmembrane α-helices

21 January 2018

1 reference

The First and Second Cytoplasmic Loops of the G-Protein Receptor, Rhodopsin, Independently Form β-Turns†

21 January 2018

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Effects of phosphorylation on the structure of the G-protein receptor rhodopsin

21 January 2018

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Solution structure of the sixth transmembrane helix of the G-protein-coupled receptor, rhodopsin11This work was supported by National Institutes of Health Grant EY03328 and in part by CA16056

21 January 2018

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Detergent-free membrane protein crystallization

21 January 2018

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Solution Conformation of CCK9, a Cholecystokinin Analog

21 January 2018

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Projection structure of rhodopsin

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1002/MED.1018

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1 August 2017

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